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Peer Reviewed Scientific Research Reports.
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1. Evaluation of two methods for generating cRNA for microarray experiments from nanogram amounts of total RNA.
Match Strength: 3.023
Several methods have been developed for amplification of RNA, making it possible to use cDNA microarrays for analysis of samples limited in amount of total RNA. The most widely used amplification protocol, the Eberwine method, amplifies RNA in a linear manner through in vitro transcription (IVT). However, when starting material is limited to nanogram amounts of total RNA, several rounds of amplification are necessary, making this method both expensive and labor-intensive. Amplification by PCR is robust and is able to amplify extremely limiting material. However, it is possible that the ... Read More »
» Published in Anal Biochem. 2006 Nov 1;358(1):111-9. Epub 2006 Sep 7.
2. Total lower eyelid reconstruction using paranasal flap.
Match Strength: 2.841
The main aim of this study is to evaluate the advantages, disadvantages, and aesthetic results of the total lower eyelid reconstruction with paranasal flap. The other reconstruction methods are also revisited.Ten patients, who were operated for the reconstruction of total lower eyelid defects between November, 1999 and April, 2005 in our department were included in this study. The total lower eyelid defects of all patients were reconstructed using paranasal flap for anterior lamella and chondromucosal, chondrocutaneous or mucosal graft for posterior lamella. Follow-up time was ranged between 3 ... Read More »
» Published in J Craniofac Surg. 2006 Sep;17(5):1020-6.
3. Quantitation of fatty acids, sterols, and tocopherols in turpentine (Pistacia terebinthus Chia) growing wild in Turkey.
Match Strength: 2.762
The chemical composition (fatty acids, tocopherols, and sterols) of the oil from 14 samples of turpentine (Pistacia terebinthus L.) fruits is presented in this study. The oil content of the samples varied in a relatively small range between 38.4 g/100 g and 45.1 g/100 g. The dominating fatty acid of the oil is oleic acid, which accounted for 43.0 to 51.3% of the total fatty acids. The total content of vitamin E active compounds in the oils ranged between 396.8 and 517.7 mg/kg. The predominant isomers were alpha- and gamma-tocopherol, with approximate equal amounts between about 110 and 150 mg ... Read More »
» Published in J Agric Food Chem. 2006 Oct 4;54(20):7667-71.
4. Total antioxidant status and oxygen free radicals during hepatic regeneration.
Match Strength: 2.706
OBJECTIVES: The damage induced by oxygen free radicals (OFRs) is caused by an imbalance of the production of versus the antioxidant defenses against OFRs. METHODS: To understand hepatic damage induced by oxygen free radicals after hepatectomy in rats, total antioxidant status and total production of oxygen free radicals were serially measured in regeneration liver. At 1, 2, 3, 7, and 10 days after hepatectomy of Sprague-Dawley rats, blood was obtained into a capillary tube from a tail vein. Total antioxidant status and total production of oxygen free radicals were measured using the Randox kit ... Read More »
» Published in Transplant Proc. 2006 Sep;38(7):2214-5.
5. The relative stress scale, a useful instrument to identify various aspects of carer burden in dementia?
Match Strength: 2.661
OBJECTIVE: To identify carer and patient characteristics associated with various aspects of burden of care. METHOD: The burden on 196 carers, each caring for one patient with dementia, was rated by means of the Relative Stress Scale (RSS). Patients were assessed with the Mini Mental State Examination (MMSE), the Disability Assessment for Dementia (DAD) and the Neuropsychiatric Inventory (NPI). RESULTS: Factor analysis of the RSS resulted in three subgroups: 'emotional distress', 'social distress' and 'negative feelings'. The total NPI score contributed to the explanation of the RSS total score ... Read More »
» Published in Int J Geriatr Psychiatry. 2007 Jan;22(1):61-7.
6. Patients Preferred a Mini-Posterior THA to a Contralateral Two-Incision THA.
Match Strength: 2.630
The two-incision total hip arthroplasty (THA) technique has been touted as offering substantially faster recovery than other methods of THA, but direct comparison studies in similar groups of patients have not been done. We sought to determine if there was a difference in the early functional outcome after a two-incision THA compared to a mini-posterior THA as measured by the time to reach defined milestones of daily activity. We also evaluated which procedure the patients preferred. Twenty-six patients underwent staged bilateral total hip arthroplasties with a two-incision minimally invasive ... Read More »
» Published in Clin Orthop Relat Res. 2006 Sep 21;
7. Correlations of total pelvic spongiosa volume with both anthropometric parameters and computed tomography-based skeletal size measurements.
Match Strength: 2.506
Patient-specific dosimetry within the field of molecular radiotherapy continues to pose a challenge owing to the difficulty in predicting marrow toxicity. This study examined the correlation between total pelvic spongiosa volume (TPSV) and independent variables, which include both readily measured or calculated anthropometric parameters (AP), and image-based skeletal measurements requiring computed tomography (CT) images or skeletal radiographs. Fourteen (14) patients (5 male and 9 female) undergoing total hip arthroplasty (THA) were subjected to modified pelvic CT scans. These scans were ... Read More »
» Published in Cancer Biother Radiopharm. 2006 Aug;21(4):352-63.
8. Factors Affecting Survival of Uncemented Total Hip Arthroplasty in Patients 50 Years or Younger.
Match Strength: 2.449
Providing a long-lasting total hip arthroplasty for patients younger than 50 years remains one of the greatest challenges for modern arthroplasty surgery. We retrospectively reviewed 221 patients younger than 50 years who underwent 299 uncemented total hip arthroplasties from 1983 to 2000. We assessed 5- to 15-year survival with revision as the endpoint. Femoral stem survival was 99.3% (range, 98.4-100%), 98.9% (range, 97.7-100%), and 96.8% (92.5-100%) at 5, 10, and 15 years, respectively. Including all component designs acetabular survival was 98.7% (range, 97.4-100%), 84.6% (78.8-90.4%), and ... Read More »
» Published in Clin Orthop Relat Res. 2006 Sep 21;
9. Can renal leukemic infiltration cause hypertension in children?
Match Strength: 2.444
Out of 334 children with acute lymphoblastic leukemia who were treated with St Jude Total XI and Total XIII chemotherapy protocols were investigated and 21 (6.3%) were hypertensive. The incidence of tumor lysis syndrome was higher in the hypertensive group than in the nonhypertensive group (28.6% vs. 11.5%) (P = 0.035). There were no differences between patients treated with high-dose methylprednisolone and prednisolone St Jude Total XI and Total XIII, St Jude Total XIII LR and St Jude Total XIII HR groups in respect of the above-mentioned parameters. Central nervous system involvement, ... Read More »
» Published in J Pediatr Hematol Oncol. 2006 Sep;28(9):579-84.
10. Low-dose radiotherapy for Stage I seminoma-long-term results.
Match Strength: 2.433
Purpose: The aim of this study was to review retrospectively the results of low-dose radiotherapy for Stage I seminoma using four different fractionation schedules and target volume definitions. Methods and Materials: A total of 191 patients underwent irradiation for histologically proven Stage I seminoma after undergoing an inguinal orchiectomy. Fractionation schedules were used one after another as follows: Total dose 30 Gy (dose/fraction 1.5 Gy, 16 patients), total dose 25.5 Gy (dose/fraction 1.5 Gy, 62 patients), total dose 20 Gy (dose/fraction 2 Gy, 69 patients), total dose 26 Gy (dose ... Read More »
» Published in Int J Radiat Oncol Biol Phys. 2006 Nov 15;66(4):1112-9. Epub 2006 Sep 18.
11. Serum prolidase activity and oxidative status in Helicobacter pylori infection.
Match Strength: 2.428
OBJECTIVES: During the course of Helicobacter pylori infection, increased oxidative stress plays an important role in the pathogenesis of gastroduodenal mucosal inflammation, which can cause gastric mucosal atrophy that characterized by the replacement of the gastric mucosal glands by collagen fibers. In the present study, we aimed to determine serum prolidase activity and oxidative status, and to find out if there is any association between serum prolidase activity and oxidative status in H. pylori infection. DESIGN AND METHODS: Forty H. pylori-positive and 32 H. pylori-negative subjects were ... Read More »
» Published in Clin Biochem. 2007 Jan;40(1-2):37-40. Epub 2006 Aug 30.
12. Increased apparent oral clearance of valproic acid during intake of combined contraceptive steroids in women with epilepsy.
Match Strength: 2.409
PURPOSE: To determine potential changes in total and unbound serum valproic acid (VPA) concentrations at steady-state during a cycle of intake of combined hormonal contraceptive (HC) steroids. METHODS: Blood samples were collected from nine women stabilized on VPA monotherapy on two separate randomized occasions: (i) at the end of the 4- to 7-day HC-free interval, and (ii) on the last day of the HC intake period. Trough concentrations of VPA in serum and serum ultrafiltrates were determined by fluorescence polarization immunoassay. RESULTS: In all women, total and unbound VPA concentrations ... Read More »
» Published in Epilepsia. 2006 Sep;47(9):1569-72.
13. Size and number of binucleate and mononucleate superior cervical ganglion neurons in young capybaras.
Match Strength: 2.404
The total number of neurons in the superior cervical ganglion (SCG) of adult capybaras is known from a previous study, where a marked occurrence of binucleate neurons (13%) was also noted. Here, distribution, number and fate of binucleate neurons were examined in younger, developing capybaras, aged 3 months. The mean neuronal cross-sectional area was 575.2 microm2 for mononucleate neurons and 806.8 microm2 in binucleate neurons. Frequency of binucleate neurons was about 36%. The mean ganglion volume was about 190 mm3 in young capybaras and the mean neuronal density was about 9,517 neurons/mm3. ... Read More »
» Published in Anat Embryol (Berl). 2006 Nov;211(6):607-17. Epub 2006 Sep 28.
14. Total synthesis of the macrocyclic cysteine knot microprotein MCoTI-II.
Match Strength: 2.398
The first total synthesis of MCoTI-II, a cysteine knot microprotein and potent trypsin inhibitor, is described; a synthetic strategy has been developed that combines efficient backbone construction via optimised solid phase peptide synthesis with one-pot 'thia-zip' native chemical ligation and refolding to yield the natural product. Publication Types: Research Support, Non-U.S. Gov ... Read More »
» Published in Chem Commun (Camb). 2006 Jul 21;(27):2848-50.
15. Efficient total syntheses and structural verification of both diospongins A and B via a common delta-lactone intermediate.
Match Strength: 2.341
The total syntheses of the two aryl C-glycoside natural products diospongins A and B are described. The key reactions involved stereoselective reductions of the appropriate oxocarbenium cations that were derived from a common delta-lactone intermediate. Publication Types: Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S ... Read More »
» Published in J Org Chem. 2006 Sep 29;71(20):7911-4.
16. Analysis of total work inability in Poland in 2000 and 2001 according to age, disease diagnosis and occupation.
Match Strength: 2.311
This study was to determine the main health-related reasons, age and occupation of those who took early retirement. This was done through an analysis of the data from Poland's Social Insurance Institution (ZUS) from 2000 and 2001. An analysis of these data showed an increase in the number of certificates confirming total inability to work in people over 40 years old. Over 50% of certificates work were issued to workers in 2 age-groups: 45-49 and 50-54. Diseases of the circulatory system, musculoskeletal system and connective tissue as well as mental and behavioural disorders are the main ... Read More »
» Published in Int J Occup Saf Ergon. 2006;12(3):231-40.
17. Future costs of stroke in the Netherlands: the impact of stroke services.
Match Strength: 2.268
OBJECTIVES: In the next decades, the number of stroke patients is expected to increase. Furthermore, organizational changes, such as stroke services, are expected to be implemented on a large scale. The purpose of this study is to estimate the future healthcare costs by taking into account the expected increase of stroke patients and a nationwide implementation of stroke services. METHODS: By means of a dynamic multistate life table, the total number of stroke patients can be projected. The model calculates the annual number of patients by age and gender. The total healthcare costs are ... Read More »
» Published in Int J Technol Assess Health Care. 2006 Fall;22(4):518-24.
18. Arabinoxylan consumption decreases postprandial serum glucose, serum insulin and plasma total ghrelin response in subjects with impaired glucose tolerance.
Match Strength: 2.265
Objective:Arabinoxylan (AX) consumption is associated with metabolic improvement during diabetes and with modulation of ghrelin, an orexigenic gut hormone. The effect of AX consumption on ghrelin secretion in disturbed metabolic states is unknown. Therefore, we investigated the postprandial responses to AX consumption of serum glucose, insulin and triglycerides and plasma total and acylated ghrelin in subjects with impaired glucose tolerance (IGT).Design:Randomized, single-blind, controlled, crossover intervention trial.Subjects:Seven female and four male adults with IGT, aged 55.5 years, and ... Read More »
» Published in Eur J Clin Nutr. 2006 Sep 20;
19. Distribution of tetrodotoxin, saxitoxin, and their analogs among tissues of the puffer fish Fugu pardalis.
Match Strength: 2.257
The anatomical distribution of tetrodotoxin (TTX), saxitoxin (STX) and their analogs (TTXs, STXs) in three female and three male specimens of the marine puffer fish Fugu pardalis from Miyagi Prefecture, 2005, Japan, were studied. 5-DeoxyTTX, 11-deoxyTTX, and 5,6,11-trideoxyTTX were quantified by liquid chromatography/mass spectrometry (LC/MS) for the first time, and other TTXs and STXs were determined by liquid chromatography-fluorescent detection (LC-FLD). As a result, 5,6,11-trideoxyTTX was found to be the major TTX analog in all tissues tested, whereas 5-deoxyTTX and 11-deoxyTTX were minor ... Read More »
» Published in Toxicon. 2006 Dec 15;48(8):980-7. Epub 2006 Aug 14.
20. Use of albumin in three French university hospitals: is prescription monitoring still useful in 2004?
Match Strength: 2.236
PURPOSE: Use of albumin (indications and quantities involved) has not been assessed in France since major changes occurred after the publication of Cochrane group meta-analysis. The objectives of this study were to measure the repartition of albumin indications in three French university hospitals in 2004 and to assess the feasibility and usefulness to implement a prescription-monitoring program. METHODS: Exhaustive record of albumin prescription during 2 months in three French university hospitals of Marseille. Inclusion of all patients with a first prescription of albumin between 15 March ... Read More »
» Published in Pharmacoepidemiol Drug Saf. 2007 Jan;16(1):79-85.
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