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1. Multiplex PCR for the detection of toxigenic cyanobacteria in dietary supplements produced for human consumption.
Match Strength: 7.234

The production of food supplements containing cyanobacteria is a growing worldwide industry. While there have been several reports of health benefits that can be gained from the consumption of these supplements, there have also been a growing number of studies showing the presence of toxins some of which (for example microcystins) are known to affect human health. In this paper, we report a multiplex polymerase chain reaction (PCR) technique that can be used to identify microcystin contamination in dietary supplements produced for human consumption. This method involves a PCR reaction ... Read More »
» Published in Appl Microbiol Biotechnol. 2007 Jan;73(5):1136-42. Epub 2006 Sep 26.

2. Vitamin D, aging, and the 2005 Dietary Guidelines for Americans.
Match Strength: 5.511

The 2005 Dietary Guidelines for Americans recommend that older adults, people with dark skin, and those exposed to insufficient ultraviolet radiation (i.e., sunlight) consume extra vitamin D from vitamin D-fortified foods and/or supplements. Individuals in these high-risk groups should consume 25 microg (1000 IU) of vitamin D daily to maintain adequate blood concentrations of 25-hydroxyvitamin D, the biomarker for vitamin D status. This review considers recommendations for vitamin D-rich foods and dietary supplements, as well as specific problems with self-prescribing sun exposure or ... Read More »
» Published in Nutr Rev. 2006 Sep;64(9):410-21.

3. A double-blind randomized controlled trial of antenatal mebendazole to reduce low birthweight in a hookworm-endemic area of Peru.
Match Strength: 4.174

OBJECTIVE: To assess the effect on birthweight of antenatal mebendazole plus iron vs. placebo plus iron in a highly hookworm-endemic area. METHODS: Double-blind, randomized controlled trial set in rural and peri-urban communities in the Peruvian Amazon region. A total of 1042 second trimester pregnant women between the ages of 18 and 44 years were recruited from April to November 2003, and followed to July 2004. Women were randomly assigned to receive either mebendazole (500 mg single dose) plus iron supplements (60 mg elemental iron daily) or placebo plus iron supplements. The primary outcome ... Read More »
» Published in Trop Med Int Health. 2006 Oct;11(10):1485-95.

4. Oxidant/antioxidant status of placenta, blood, and cord blood samples from pregnant women supplemented with iron.
Match Strength: 4.080

OBJECTIVE: In this study, it was aimed to investigate oxidant/antioxidant status in placenta and in blood and cord blood samples from pregnant women supplemented with iron during pregnancy. METHODS: For this purpose, 27 pregnant women at admission for delivery participated in the study. Fifteen of them did not take iron tablets and the others took oral iron supplements during pregnancy. Following delivery, part of the placenta and blood and cord blood samples were taken from the mothers. In these samples, oxidant parameters (malondialdehyde [MDA] levels and xanthine oxidase [XO] activities) ... Read More »
» Published in J Soc Gynecol Investig. 2006 Oct;13(7):502-5. Epub 2006 Sep 20.

5. Do probiotics have a therapeutic role in gastroenterology?
Match Strength: 3.394

Several hundred species of bacteria inhabit the gut, and affect its cell biology, morphology and homeostasis. Many bacteria are however potential pathogens, especially if the integrity of the epithelial barrier is physically or functionally breached. Conversely, the interaction between host and commensal microbes can confer important health benefits. This has led to commercial and public interest in "probiotics", live microbes principally taken as food supplements. Might probiotics also be used in disease therapy? Experimental evidence that probiotics modulate gut physiology, particularly ... Read More »
» Published in World J Gastroenterol. 2006 Sep 14;12(34):5447-57.

6. The potential for prostate cancer chemoprevention.
Match Strength: 2.970

The dramatic international variation in prostate cancer incidence and mortality rates suggests that changeable environmental factors exert an influence. This has prompted a search for ways to prevent the disease. Epidemiologic studies suggest that dietary factors such as the carotenoid lycopene, selenium, vitamin E, and high intake of fat have roles in prostate cancer risk. Several studies show that impairment of androgen synthesis lowers the risk of prostate cancer. 5-alpha-reductase inhibitors such as finasteride have been shown to decrease prostate size by decreasing androgenic stimulation ... Read More »
» Published in Rev Urol. 2002;4 Suppl 5:S11-7.

7. Mulberry extract supplements ameliorate the inflammation-related hematological parameters in carrageenan-induced arthritic rats.
Match Strength: 2.829

Mulberry fruit (Morus Lhou Koidz.), a rich source of the major anthocyanin, cyanidin 3-glucoside (C3G), has traditionally been used for the treatment of inflammatory conditions including rheumatic arthritis. In this study, we evaluated the efficacy of orally administrated methanolic mulberry fruit extract (ME) in carrageenan-induced arthritic rats, based on previously observed in vitro antioxidant and anti-inflammatory activities. A significant attenuation of hind paw inflammation characterized by fluid accumulation, uric acid production, and rheumatoid factors induced by carrageenan was ... Read More »
» Published in J Med Food. 2006 Fall;9(3):431-5.

8. Medical management of patients over 80 years admitted to orthopedic surgery for low-energy fracture.
Match Strength: 2.657

OBJECTIVE: To develop a cost-effective strategy for improving osteoporosis management in patients admitted to an orthopedic surgery department for low-energy fractures. METHODS: From November 2003 to July 2004, all patients over 50 years admitted to the orthopedics department of the Caen Teaching Hospital (France) for low-energy fractures were identified and evaluated by rheumatology department physicians in the same hospital. RESULTS: During the study period, 313 patients were identified, 257 women (mean age, 79.5+/-10.2 years) and 56 men (mean age, 74.6+/-10.8 years), each with one fracture ... Read More »
» Published in Joint Bone Spine. 2006 Jul 21;

9. Natremia of healthy term newborns at 48 h of life: influence of feeding patterns.
Match Strength: 2.614

OBJECTIVES: To describe natremia in healthy term newborns and determine whether there is a relationship between blood sodium and feeding patterns. METHODS: All normal newborns, admitted to the nursery between January and March 2004 were eligible for this prospective cohort study. Inclusion criteria were: > or =37 weeks of gestational age, birth weight > or =2500 g, Apgar scores > or =7 at 5 and 10 min and normal physical examination. A capillary blood sample was taken at 48+/-12 h of life. RESULTS: Blood samples from 126 newborns were analyzed. Mean gestational age was 39.6 weeks, ... Read More »
» Published in Clin Biochem. 2006 Oct;39(10):992-6. Epub 2006 Jul 22.

10. Effects of L-arginine oral supplements in pregnant spontaneously hypertensive rats.
Match Strength: 2.521

PURPOSE: To evaluate the effects of L-arginine oral supplementation in spontaneously hypertensive pregnant rats (SHR). METHODS: Thirty SHR and ten Wistar-EPM-1 virgin female rats were used in the study. Before randomization, females were caged with males of the same strain (3:1). Pregnancy was confirmed by sperm-positive vaginal smear (Day 0). Wistar-EPM-1 rats served as counterpart control (C-1). SHR rats were randomized in 4 groups (n=10): Group Control 2, non-treated rats; Group L-Arginine treated with L-arginine 2%; Group Alpha-methyldopa treated with Alpha-methyldopa 33 mg/Kg; Group L ... Read More »
» Published in Acta Cir Bras. 2006 Sep-Oct;21(5):291-5.

11. Addressing the soy and breast cancer relationship: review, commentary, and workshop proceedings.
Match Strength: 2.419

The impact of soyfood intake on breast cancer risk has been investigated extensively. Much of this focus can be attributed to the soybean being a dietary source that is uniquely rich in isoflavones. The chemical structure of isoflavones is similar to that of estrogen, and isoflavones bind to both estrogen receptors (ER alpha and ER beta) (although they preferentially bind to and activate ER beta) and exert estrogen-like effects under some experimental conditions. Isoflavones also possess nonhormonal properties that are associated with the inhibition of cancer cell growth. Thus, there are ... Read More »
» Published in J Natl Cancer Inst. 2006 Sep 20;98(18):1275-84.

12. The effect of exercise and training status on platelet activation: do cocoa polyphenols play a role?
Match Strength: 2.347

Sedentary and trained men respond differently to the same intensity of exercise, this is probably related to their platelet reactivity and antioxidant capacity. There is growing interest in the utilization of antioxidant-rich plant extracts as dietary food supplements. The aim of this study was to investigate the effect of an acute bout of sub maximal exercise on platelet count and differential response of platelet activation in trained and sedentary subjects and to observe if cocoa polyphenols reverse the effect of exercise on platelet function. The practical significance of this study was ... Read More »
» Published in Platelets. 2006 Sep;17(6):361-7.

13. Vaginal microflora in postmenopausal women on hormone replacement therapy.
Match Strength: 2.297

To study the spectrum of vaginal microflora in postmenopausal women on hormone replacement therapy (HRT) and to compare the efficacy of Papanicolaou (Pap) smears with other methods for their detection. Eighty postmenopausal women were recruited for the study. These included 40 women who had attained spontaneous and were on HRT (User 1); 20 hysterectomised women on only estrogen therapy (User 2) and 20 controls (Non users). Their clinical data was recorded and specimens were collected for vaginal cultures (for aerobic bacteria and fungi), vaginal pH, Gram stain and Pap stain on cervical-vaginal ... Read More »
» Published in Indian J Pathol Microbiol. 2006 Jul;49(3):457-61.

14. Combined effects of maternal smoking status and dietary intake related to weight gain and birth size parameters.
Match Strength: 2.292

OBJECTIVE: To investigate the interaction of smoking status and dietary intake during pregnancy and its relationship to maternal weight gain and birth size parameters. DESIGN: An observational prospective study. SETTING: Free-living conditions. POPULATION: Four hundred and eight healthy pregnant Icelandic women. METHODS: Maternal smoking status, lifestyle factors and dietary habits were evaluated with questionnaires. Intake of foods and supplements was also estimated with a semiquantitative food frequency questionnaire for the previous 3 months. All questionnaires were filled out between 11 ... Read More »
» Published in BJOG. 2006 Nov;113(11):1296-302. Epub 2006 Sep 27.

15. The VSL#3 probiotic formula induces mucin gene expression and secretion in colonic epithelial cells.
Match Strength: 2.183

Several studies have stressed the importance of the microbiota in the maintenance of the gastrointestinal epithelium. Administration of probiotic bacteria, supplements composed of microbiota constituents, was previously shown to diminish symptoms in patients suffering from inflammatory bowel diseases. This raises the possibility that probiotics may play an active role in enhancing the intestinal barrier at the mucosal surface. In this study, we investigated whether the clinically tested VSL#3 probiotic formula and/or its secreted components can augment the protective mucus layer in vivo and in ... Read More »
» Published in Am J Physiol Gastrointest Liver Physiol. 2007 Jan;292(1):G315-22. Epub 2006 Sep 14.

16. Fracture incidence and characterization in patients on osteoporosis treatment: the ICARO study.
Match Strength: 2.041

None of the available osteoporosis therapies have been shown to completely abolish the risk of fractures. In clinical practice, the outcome may be even poorer. In 880 patients prescribed with antiresorptives (alendronate, risedronate, and raloxifene) for >1 year, a fragility fracture was recorded in 8.9%/year of them. This incidence is considerably higher than that observed in randomized clinical trials, and it was significantly related to poor compliance and lack of supplementation with calcium and vitamin D. INTRODUCTION: Osteoporotic fracture is one of the most important public health ... Read More »
» Published in J Bone Miner Res. 2006 Oct;21(10):1565-70.

17. Prostate cancer incidence and intake of fruits, vegetables and related micronutrients: the multiethnic cohort study* (United States).
Match Strength: 2.031

OBJECTIVE: To describe the relationship between the intake of fruits, vegetables, and related vitamins and antioxidants, and the risk of prostate cancer in male participants in a large multiethnic cohort study. METHODS: Food and nutrient intakes in 1993-1996 were calculated from a detailed food frequency questionnaire (FFQ) designed to account for the food and nutrient intake of the ethnic groups represented in the study (82,486 African-American, Japanese-American, Native-Hawaiian, Latino and White males included here). Follow-up for incident cancers utilized local SEER registries. Vital ... Read More »
» Published in Cancer Causes Control. 2006 Nov;17(9):1193-207.

18. Topical fluoride guidance.
Match Strength: 1.685

SCOPE AND PURPOSE: To review the scientific evidence and develop clinical recommendations on professionally applied topical fluoride. METHODOLOGY: Medline and the Cochrane Database of Systematic Reviews were searched for systematic reviews published in the English language that dealt with professionally applied topical fluoride, including gel, foam or varnish, at any time up to October 2005. Seventeen systematic reviews were identified. Clinical studies published after January 2004 and thus not included in the systematic reviews were also identified through Medline. The American Dental ... Read More »
» Published in Evid Based Dent. 2006;7(3):62-4. Comment on: J Am Dent Assoc. 2006 Aug;137(8):1151-9.

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* All information on Level1Diet.com is for educational purposes only. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Before changing your diet, or adding supplements to your diet, or beginning an exercise program, everyone should consult a qualified and licensed health practitioner; a physician, dietician or similar professional.



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Replace omega-6 vegetable oils with omega-9 olive oil... Eat oily fish like tuna, sardines, anchovy, salmon, herring... Beans, lentils, peas add fiber... Nine or more 3-ounce servings of fruits or vegetables per day...