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Peer Reviewed Scientific Research Reports.
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1. The responsibilities and rights of dental professionals 3. Professional rights.
Match Strength: 3.647
Professional status, professional autonomy, clinical freedom, self-regulation and the right to serve patients and the community seem to be the main rights of dentists. Although they simply may be seen as privileges that are related to being a dentist, these rights cannot be considered independent from dentists' roles and responsibilities. They are, in fact, valuable tools that serve dentists to meet their broad responsibilities that arise from the 'social contract' between the profession and the public ... Read More »
» Published in Int Dent J. 2006 Aug;56(4):224-6.
2. Structure and phase behavior of Widom-Rowlinson model calculated from a nonuniform Ornstein-Zernike equation.
Match Strength: 3.035
The second-order integral-equation formalism of [Attard J. Chem. Phys. 91, 3072 (1989); 95, 4471 (1991)], applied previously to one-component hard spheres and Lennard-Jones fluids, as well as to their mixtures, is used to binary Widom-Rowlinson mixtures. Comparison with Monte Carlo simulations of the pair correlation functions and of the demixing phase diagram shows that this method is also quite accurate in the case of highly nonadditive mixtures. Moreover, the results of the second-order theory are compared with previous theoretical predictions. Our interest is also in the calculation of the ... Read More »
» Published in J Chem Phys. 2006 Sep 21;125(11):114505.
3. Effect of atorvastatin on antibody, interleukin-4 and gamma-interferon production in mice immunized with egg albumin.
Match Strength: 2.989
Three-hydroxy-3-methylglutaryl CoA reductase inhibitors, also known as statins, are widely used as the drug of choice for the treatment of hyperlipidemia. However, actions beyond that of simply lowering cholesterol levels have been reported. This study aims at evaluating the effect of atorvastatin on antibody interleukin-4 and gamma-interferon production in mice immunized with egg albumin. Antibody levels were determined by an enzyme linked immunosorbent assay and cytokine transcripts by reverse transcriptase-polymerase chain reaction. Results indicated that repeated daily doses of 40 mg/Kg ... Read More »
» Published in Immunopharmacol Immunotoxicol. 2006;28(3):459-70.
4. Double half-cubane copper(II) complexes available from copper(II) 1,1,1,5,5,5-hexafluoropentane-2,4-dionate dissolved in formamides.
Match Strength: 2.900
Tetranuclear copper(II) complexes were obtained after simply dissolving [Cu(hfac)2] in formamide-methanol mixed solvents (Hhfac=1,1,1,5,5,5-hexafluoropentane-2,4-dione). X-Ray diffraction studies revealed that they possessed a tetranuclear double half-cubane core sandwiched with two trianionic ligands from 2,4,6-tris(trifluoromethyl)tetrahydropyran-2,4,6-triol (H3ttpt). Complexes [Cu4(ttpt)2(hfac)2(dmf)2.5], [Cu4(ttpt)2(tfa)2(def)4], and [Cu4(ttpt)2(hfac)2(H2O)4](fa) were prepared from N,N-dimethylformamide(dmf)-MeOH, N,N-diethylformamide (def)-MeOH, and formamide(fa)-MeOH (Htfa ... Read More »
» Published in Dalton Trans. 2006 Oct 7;(37):4438-43. Epub 2006 Aug 14.
5. Testosterone replacement in men with andropause: an overview.
Match Strength: 2.805
Serum testosterone levels decline progressively as men age, with resulting pathophysiological changes. Because the onset of andropause is gradual and many of its symptoms mirror those associated with medications or disease states common in the elderly, a clinical diagnosis can be difficult to make. Additionally, because of a lack of established normal testosterone levels for different age groups, as well as confusion regarding what subset of testosterone to measure, simply testing testosterone levels is inadequate. Although clinical studies have shown testosterone supplementation to be safe, ... Read More »
» Published in Rev Urol. 2004;6 Suppl 6:S9-S15.
6. 'They're not racist ...' prejudice denial, mitigation and suppression in dialogue.
Match Strength: 2.759
Social scientific work on the suppression, mitigation or denial of prejudiced attitudes has tended to focus on the strategic self-presentation and self-monitoring undertaken by individual social actors on their own behalf. In this paper, we argue that existing perspectives might usefully be extended to incorporate three additional considerations. First, that social actors may, on some occasions, act to defend not only themselves, but also others from charges of prejudice. Second, that over the course of any social encounter, interactants may take joint responsibility for policing conversation ... Read More »
» Published in Br J Soc Psychol. 2006 Sep;45(Pt 3):441-62.
7. Sampling realistic protein conformations using local structural bias.
Match Strength: 2.705
The prediction of protein structure from sequence remains a major unsolved problem in biology. The most successful protein structure prediction methods make use of a divide-and-conquer strategy to attack the problem: a conformational sampling method generates plausible candidate structures, which are subsequently accepted or rejected using an energy function. Conceptually, this often corresponds to separating local structural bias from the long-range interactions that stabilize the compact, native state. However, sampling protein conformations that are compatible with the local structural bias ... Read More »
» Published in PLoS Comput Biol. 2006 Sep 22;2(9):e131. Epub 2006 Aug 21.
8. Human hepatic sinusoidal endothelial cells can be distinguished by expression of phenotypic markers related to their specialised functions in vivo.
Match Strength: 2.615
The hepatic sinusoids are lined by a unique population of hepatic sinusoidal endothelial cells (HSEC), which is one of the first hepatic cell populations to come into contact with blood components. However, HSEC are not simply barrier cells that restrict the access of blood-borne compounds to the parenchyma. They are functionally specialised endothelial cells that have complex roles, including not only receptor-mediated clearance of endotoxin, bacteria and other compounds, but also the regulation of inflammation, leukocyte recruitment and host immune responses to pathogens. Thus understanding ... Read More »
» Published in World J Gastroenterol. 2006 Sep 14;12(34):5429-39.
9. A test for hydrotropic behavior by roots of two coastal dune shrubs.
Match Strength: 2.597
Root hydrotropism could be a means by which plants forage for limited and patchy distributions of soil water. While root hydrotropism has been induced in distinctly artificial conditions, it is unclear if it operates in natural settings. Here, we tested for this possibility in seedlings of two species of dune shrubs. Growth of individual roots in sand-filled observation chambers was monitored in response to moisture-rich patches and resultant soil water gradients. Chambers were designed so that roots could intercept the moisture gradients but not the moisture-rich patches simply through ... Read More »
» Published in New Phytol. 2006;172(2):358-68.
10. A wave of reactive oxygen species (ROS)-induced ROS release in a sea of excitable mitochondria.
Match Strength: 2.525
Once considered simply as the main source of ATP, mitochondria are now implicated in the control of many additional aspects of cell physiology, such as calcium signaling, and pathology, as in injury incurred on ischemia and subsequent reperfusion (I/R). Mitochondrial respiration is ordinarily accompanied by low-level ROS production, but they can respond to elevated ROS concentrations by increasing their own ROS production, a phenomenon termed ROS-induced ROS release (RIRR). Two modes of RIRR have been described. In the first mode of RIRR, enhanced ROS leads to mitochondrial depolarization via ... Read More »
» Published in Antioxid Redox Signal. 2006 Sep-Oct;8(9-10):1651-65.
11. Obesity, waist-hip ratio and hunter-gatherers.
Match Strength: 2.501
Obesity is a rapidly growing global problem. It is not simply the result of eating too much, and not all types of obesity have the same significance. Obesity is in part genetic, and one particularly important genetic type of obesity is the tendency to 'truncal obesity',-that is, a raised waist-to-hip ratio. Such obesity is powerfully associated not only with a tendency to diabetes, but also to cardiovascular disease, ('Syndrome X'). Interestingly, this is the type of obesity seen in every hunter-gatherer (HG) population around the globe. Such people are intolerant of carbohydrate, especially ... Read More »
» Published in BJOG. 2006 Oct;113(10):1110-6.
12. Is high-spatial frequency information used in the early stages of face detection?
Match Strength: 2.465
The present study examined the role of high-spatial frequency information in early face processing, as indexed by the N170 face-sensitive ERP component. Participants detected 4 versions of famous faces, including full spectrum faces, and bandpass filtered faces containing predominantly high-spatial frequencies, low-spatial frequencies or both. The power spectra of all stimuli were balanced by superimposing the faces onto a visual noise background that included the spatial frequency information that was missing in filtered faces, e.g., high-spatial frequency faces were presented on a high- and ... Read More »
» Published in Brain Res. 2006 Oct 30;1117(1):154-61. Epub 2006 Sep 26.
13. Phosphatidylinositol 4-phosphate is required for translation initiation in Saccharomyces cerevisiae.
Match Strength: 2.453
The small natural product wortmannin inhibits protein synthesis by modulating several phosphatidylinositol (PI) metabolic pathways. A primary target of wortmannin in yeast is the plasma membrane-associated PI 4-kinase (PI4K) Stt4p, which is required for actin cytoskeleton organization. Here we show that wortmannin treatment or inactivation of Stt4p, but not disorganization of the actin cytoskeleton per se, leads to a rapid attenuation of translation initiation. Interestingly, inactivation of Pik1p, a wortmannin-insensitive, functionally distinct PI4K, implicated in the regulation of Golgi ... Read More »
» Published in J Biol Chem. 2006 Dec 15;281(50):38139-49. Epub 2006 Sep 27.
14. Locomotion by Abdopus aculeatus (Cephalopoda: Octopodidae): walking the line between primary and secondary defenses.
Match Strength: 2.404
Speeds and variation in body form during crawling, bipedal walking, swimming and jetting by the shallow-water octopus Abdopus aculeatus were compared to explore possible interactions between defense behaviors and biomechanics of these multi-limbed organisms. General body postures and patterns were more complex and varied during the slow mode of crawling than during fast escape maneuvers such as swimming and jetting. These results may reflect a trade-off between predator deception and speed, or simply a need to reduce drag during jet-propelled locomotion. Octopuses swam faster when ... Read More »
» Published in J Exp Biol. 2006 Oct;209(Pt 19):3697-707.
15. Diabetic foot disease.
Match Strength: 2.296
OBJECTIVE: To review the spectrum of foot problems in patients with diabetes and the underlying etiologic factors. METHODS: In this review, the term "diabetic foot disease" (DFD) will be used (previously referred to as simply "diabetic foot"). The relevant anatomy of the foot is discussed, the clinical evaluation and severity of DFD are outlined, and the role of both systemic control and local measures in the management of DFD is addressed. RESULTS: DFD is linked with a wide variety of etiologic associations, pathologic forms, and clinical severity. The causes of DFD include such factors as ... Read More »
» Published in Endocr Pract. 2006 Sep-Oct;12(5):583-92.
16. Modeling brominated trihalomethane compounds in drinking water at a treatment plant in Beaumont, Texas.
Match Strength: 2.268
The premise of this study is that the presence of bromide has a substantial effect on both the speciation and total formation of trihalomethane (THM). Consequently, models of water containing substantial bromide concentrations require refinement because they are only calibrated with raw water with high humic acid content. This study investigates and reports efforts on such refinement. The objectives of work reported in this paper are to formulate and validate a new correlative model that is based on physical principles and incorporates high levels of bromide that affect THM formation using raw ... Read More »
» Published in J Environ Sci Health A Tox Hazard Subst Environ Eng. 2006;41(11):2429-45.
17. Just a phase they're going through: The complex interaction of intrinsic high-threshold bursting and gap junctions in the generation of thalamic alpha and theta rhythms.
Match Strength: 2.244
Rhythms in the alpha frequency band (8-13 Hz) are a defining feature of the human EEG during relaxed wakefulness and are known to be influenced by the thalamus. In the early stages of sleep and in several neurological and psychiatric conditions alpha rhythms are replaced by slower activity in the theta (3-7 Hz) band. Of particular interest is how these alpha and theta rhythms are generated at the cellular level. Recently we identified a subset of thalamocortical (TC) neurons in the lateral geniculate nucleus (LGN) which exhibit rhythmic high-threshold (>-55 mV) bursting at approximately 2 ... Read More »
» Published in Int J Psychophysiol. 2006 Sep 22;
18. Endogenous endothelins and the response to electrical renal nerve stimulation in anaesthetized rabbits.
Match Strength: 2.224
The influence of endogenous endothelins on the neural control of renal function is poorly understood. We therefore studied the effects of endothelin blockade (combined ET(A) and ET(B) receptor antagonism using TAK-044) on the acute and prolonged effects of renal nerve stimulation in rabbits, measuring renal blood flow, glomerular filtration rate (GFR), urine flow and sodium excretion. Brief (3 min) stimulation over 0.5-8 Hz produced frequency-dependent reductions in total renal blood flow, cortical blood flow and, less markedly, medullary blood flow. TAK-044 did not significantly alter basal ... Read More »
» Published in Auton Neurosci. 2006 Sep 13;
19. Implantation of a scaffold following bulbectomy induces laminar organization of regenerating olfactory axons.
Match Strength: 2.216
Primary olfactory axons expressing different odorant receptors are interspersed within the olfactory nerve. However, upon reaching the outer nerve fiber layer of the olfactory bulb they defasciculate, sort out, and refasciculate prior to targeting glomeruli in fixed topographic positions. While odorant receptors are crucial for the final targeting of axons to glomeruli, it is unclear what directs the formation of the nerve fiber and glomerular layers of the olfactory bulb. While the olfactory bulb itself may provide instructive cues for the development of these layers, it is also possible that ... Read More »
» Published in Brain Res. 2006 Nov 13;1119(1):58-64. Epub 2006 Sep 25.
20. The SL1-SL2 (stem-loop) domain is the primary determinant for stability of the gamma retroviral genomic RNA dimer.
Match Strength: 2.202
Retroviral genomes are assembled from two sense-strand RNAs by noncovalent interactions at their 5' ends, forming a dimer. The RNA dimerization domain is a potential target for antiretroviral therapy and represents a compelling RNA folding problem. The fundamental dimerization unit for the Moloney murine sarcoma gamma retrovirus spans a 170-nucleotide minimal dimerization active sequence. In the dimer, two self-complementary sequences, PAL1 and PAL2, form intermolecular duplexes, and an SL1-SL2 (stem-loop) domain forms loop-loop base pairs, mediated by GACG tetraloops, and extensive tertiary ... Read More »
» Published in J Biol Chem. 2006 Dec 8;281(49):37952-61. Epub 2006 Sep 19.
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