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Obesity
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1. Impact of obesity on radiology.
Match Strength: 6.917

Obesity is impacting radiology departments throughout the country. Increasingly, the ability to acquire and interpret images is compromised by a patient's body habitus. This article provides radiologists with background information about obesity including the definition of obesity, the prevalence of obesity, and the health and economic implications; describes current problems and provides specific solutions related to imaging obese patients using various modalities; and discusses the future of medical imaging and obesity ... Read More »
» Published in Radiol Clin North Am. 2007 Mar;45(2):231-46.

2. Variation in FTO contributes to childhood obesity and severe adult obesity.
Match Strength: 6.803

We identified a set of SNPs in the first intron of the FTO (fat mass and obesity associated) gene on chromosome 16q12.2 that is consistently strongly associated with early-onset and severe obesity in both adults and children of European ancestry with an experiment-wise P value of 1.67 x 10(-26) in 2,900 affected individuals and 5,100 controls. The at-risk haplotype yields a proportion of attributable risk of 22% for common obesity. We conclude that FTO contributes to human obesity and hence may be a target for subsequent functional analyses ... Read More »
» Published in Nat Genet. 2007 Jun;39(6):724-6. Epub 2007 May 13.

3. Obesity and kidney transplantation.
Match Strength: 6.766

Obesity is an increasingly common comorbidity at the time of kidney transplantation. Obesity is also a frequent complication of kidney transplantation. The obese transplant recipient suffers adverse metabolic and cardiovascular consequences of obesity. These metabolic and cardiovascular sequelae of obesity are major contributors to morbidity and mortality after kidney transplantation. We discuss the epidemiology and pathophysiology of obesity in the kidney transplant recipient and provide an overview of clinical studies on obesity in kidney transplantation. An approach to obesity in renal ... Read More »
» Published in Contrib Nephrol. 2006;151:19-41.

4. Obesity after spinal cord injury.
Match Strength: 6.741

America is in the midst of an obesity epidemic, and individuals who have spinal cord injury (SCI) are perhaps at greater risk than any other segment of the population. Recent changes in the way obesity has been defined have lulled SCI practitioners into a false sense of security about the health of their patients regarding the dangers of obesity and its sequelae. This article defines and uses a definition of obesity that is more relevant to persons who have SCI, reviews the physiology of adipose tissue, and discusses aspects of heredity and environment that contribute to obesity in SCI. The ... Read More »
» Published in Phys Med Rehabil Clin N Am. 2007 May;18(2):333-51, vii.

5. Evaluation of Obesity. Who Are the Obese?
Match Strength: 6.722

Obesity has become increasingly prevalent in westernized countries, and in the United States it has reached epidemic proportions. The risks linked to obesity--such as cardiovascular disease, hypertension, and type 2 diabetes--make this condition one that deserves time and recognition by primary care physicians. Here, Dr Bray reviews the characteristics that define overweight and obesity, the factors that contribute to the pathogenesis of obesity, and current approaches to its management ... Read More »
» Published in Postgrad Med. 2003 Dec;114(6):19-27, 38.

6. Adolescent obesity in Lebanese private schools.
Match Strength: 6.641

BACKGROUND: Obesity has become a public health problem worldwide. Our objective was to calculate the prevalence of overweight and obesity. METHODS: It is a cross sectional study of adolescents in private Lebanese schools, aged 10-18 years. Gender, birth date and measures of weight and height were recorded. RESULTS: In 12,299 adolescents, we found high prevalence of obesity (7.5%) and at risk of obesity (24.4%). In girls, risk of obesity and obesity prevalence decrease with increasing age (P < 10(-4)) as compared with that in boys. CONCLUSION: Early recognition of obesity should become ... Read More »
» Published in Eur J Public Health. 2006 Dec;16(6):648-51. Epub 2006 May 12.

7. Obesity: surgical management.
Match Strength: 6.640

Obesity surgery is the most cost-effective form of treatment for morbid obesity. Unfortunately the NHS has failed to provide widespread comprehensive assessment and obesity surgical services. As a result we are lagging behind many developed countries to the detriment of our patients. Publication Types: ... Read More »
» Published in Br J Hosp Med (Lond). 2007 Feb;68(2):85-8.

8. Obesity and Asthma: Cause for Concern
Match Strength: 6.605

Epidemiological data indicate that obesity is a risk factor for incident asthma, and that obesity is also associated with increased asthma severity. Importantly, obesity antedates asthma. The observations that weight loss improves asthma and that obese mice have innate airway hyperresponsiveness and increased responses to asthma triggers also support a relationship between obesity and asthma. The basis for this relationship is unknown, but might be the result of common etiologies, comorbidities, effects of obesity on lung volume or adipokines. Understanding the mechanistic basis for the ... Read More »
» Published in Curr Opin Pharmacol. 2006 Jun;6(3):230-6. Epub 2006 Mar 9.

9. Obesity: selected medical issues.
Match Strength: 6.563

The prevalence of obesity is rising at a very alarming rate in the United States. Estimates are that 27% of American adults are now considered obese, and another 52% are overweight. These individuals are at increased risk of premature mortality and the development of many comorbid illnesses. Numerous factors contribute to this epidemic. The medical treatment of obesity is difficult, but can be successful. Drug therapy and obesity surgery can be effective but more research is needed to improve all of the obesity treatments ... Read More »
» Published in Eat Disord. 2003 Winter;11(4):317-30.

10. Pulmonary considerations in obesity and the bariatric surgical patient.
Match Strength: 6.563

Severe obesity can be associated with significant alterations in normal cardiopulmonary physiology. The pathophysiologic effects of obesity on a patient's pulmonary function are multiple and complex. The impact of obesity on morbidity and mortality are often underestimated. Bariatric surgery has been shown to be the most effective modality of reliable and durable treatment for severe obesity. Surgical weight loss improves and, in most cases, completely resolves the pulmonary health problems associated with obesity. Publication Types: ... Read More »
» Published in Med Clin North Am. 2007 May;91(3):433-42, xi.

11. Introduction: Obesity: Diet Composition, Energy Expenditure, and Treatment of the Obese Patient
Match Strength: 6.521

The association of obesity with increased risks for developing hypertension, diabetes, cardiovascular disease, and cancer has made it a complex health problem. Exacerbating the problem is the realization that there are multiple factors, both physiological and psychological, that interact to induce obesity, as well as a myriad of components that may be useful in the curtailment of obesity. The aim of this symposium is to provide a wider understanding of the elements behind the development and reduction of obesity ... Read More »
» Published in Med Sci Sports Exerc. 1991 Mar;23(3):273-4.

12. Infectobesity: obesity of infectious origin.
Match Strength: 6.520

In the U.S., the prevalence of obesity increased by 30% from 1980 to 1990, and this increase appears to be continuing. Although obesity has multiple etiologies, an overlooked possibility is obesity of an infectious origin. Six pathogens are reported to cause obesity in animals. Canine distemper virus was the first virus reported to cause obesity in mice, followed by Rous-associated virus-7, an avian retrovirus, which has been shown to cause stunting, obesity and hyperlipidemia in chickens. Next, the obesity-promoting effect of Borna disease virus was demonstrated in rats. Scrapie agents were ... Read More »
» Published in J Nutr. 2001 Oct;131(10):2794S-2797S.

13. Prevalence of obesity in Kuwait and its relation to sociocultural variables.
Match Strength: 6.490

This study ascertains the prevalence of obesity and its relationship with some sociocultural characteristics in Kuwaiti society. The sample involved 212 men and 212 women, most of whom are overweight and obese. Grades 1 (body mass index [BMI] > 25-30 kg m(-2)), 2 (BMI > 30-40) and 3 (BMI > 40) of obesity characterize 71.2% of the sample. Most individuals are in grade 2 obesity, 37.2%. Grade 1 obesity is seen in 31.4% of the sample. Obesity increases with age, especially in women. The heaviest women are aged 60 years or older (mean BMI of 33.8), about the same mean as in the 50-59-year ... Read More »
» Published in Obes Rev. 2006 May;7(2):147-54.

14. Fat nation: Deciphering the distinctive geographies of obesity in England.
Match Strength: 6.476

Much attention is focused on obesity by both the media and by public health. As a health risk, obesity is recognised as a contributing factor to numerous health problems. Recent evidence points to a growth in levels of obesity in many countries and particular attention is usually given to rising levels of obesity among younger people. England is no exception to these generalisations with recent studies revealing a clear geography to what has been termed an 'obesity epidemic.' This paper examines the complexities inherent in the geography of adult obesity in England. Existing knowledge about ... Read More »
» Published in Soc Sci Med. 2007 Jul;65(1):20-31. Epub 2007 Apr 27.

15. Contemporary Surgical Management of Obesity
Match Strength: 6.416

The incidence of overweight and obesity is reaching epidemic proportions in the United States. The morbidity of obesity greatly influences the lives of those with this disease and upon the healthcare systems treating those afflicted with it. Currently, medical therapies are ineffective in both the prevention and treatment of obesity. Bariatric surgery has gained immense popularity over the past decade as it has been shown to be among the few means for which obesity can be successfully treated. This article reviews the current state of the art of bariatric surgery ... Read More »
» Published in W V Med J. 2002 Nov-Dec;98(6):273-7.

16. Obesity and target organ damage: the kidney
Match Strength: 6.335

Obesity is a risk marker for progressive renal function loss in patients with known renal disease. There is, however, increasing evidence that obesity may also damage the kidney in otherwise healthy subjects. There appears to be an intriguing parallel between the renal effects of obesity and those of diabetes. First, an increased renal blood flow and glomerular filtration rate has been described in obesity and, second, microalbuminuria is found to be related to obesity. These two events are known to predict future loss of renal function in diabetes. The mechanism responsible for the renal ... Read More »
» Published in Int J Obes Relat Metab Disord. 2002 Dec;26 Suppl 4:S21-4.

17. The Obesity Hypoventilation Syndrome
Match Strength: 6.334

The obesity hypoventilation syndrome, which is defined as a combination of obesity and chronic hypoventilation, utimately results in pulmonary hypertension, cor pulmonale, and probable early mortality. Since the classical description of this syndrome nearly fifty years ago, research has led to a better understanding of the pathophysiologic mechanisms involved in this disease process, and to the development of effective treatment options. However, recent data indicate the obesity hypoventilation syndrome is under-recognized, and under-treated. Because obesity has become a national epidemic, it ... Read More »
» Published in Am J Med. 2005 Sep;118(9):948-56.

18. Prevalence of obesity in Great Britain.
Match Strength: 6.333

Since 1980 the prevalence of obesity in Great Britain in adults has almost trebled. Latest figures show that 23% of men and 25% of women were obese in 2002. In children, obesity prevalence is lower but the increase in the prevalence of overweight is similar to the rise in obesity in adults. Data from national surveys also show that there are marked differences in the prevalence of obesity that underpin health inequalities. Obesity is higher in low social classes, some ethnic minority groups particularly from South Asia and in Scotland and Wales relative to England. Publication Types: ... Read More »
» Published in Obes Rev. 2005 Feb;6(1):11-2.

19. Molecular links between obesity and cardiovascular disease.
Match Strength: 6.331

Obesity is a recognized risk factor for cardiovascular disease. Because the prevalence of obesity is rising in industrialized as well as developing nations, it is important to understand the mechanisms by which obesity targets the vascular system. A metabolic syndrome of insulin resistance is provoked by obesity, and this results in the dysregulation of a number of adipocyte-derived factors, which favors atherosclerosis. This review focuses on how products of the adipocyte, including free fatty acids and "adipo"-cytokines, may mediate the effect of obesity on insulin resistance and ... Read More »
» Published in Am J Ther. 2002 Nov-Dec;9(6):516-21.

20. The infrastructure of obesity and the obesity epidemic : implications for public policy.
Match Strength: 6.322

If present increases in the rate of obesity persist, by 2015 half of the population in the US could be obese. This article presents the case that the reason for the epidemic is an 'infrastructure of obesity' that fuels the phenomenon. To control this epidemic, public policy in general and health policy in particular need to shift from market oriented policies that favour individual choice to policies that regulate the food supply, to help dismantle the infrastructure of obesity. Our research shows that state regulations have made some progress in the fight against obesity ... Read More »
» Published in Appl Health Econ Health Policy. 2005;4(3):139-46.

21. Obesity and cardiovascular risk factors among men and women aged 40 years and older in a rural area of Japan.
Match Strength: 6.312

Obesity is one of the most common health problems, and is recognized worldwide as an "escalating epidemic." For the establishment of an obesity-prevention strategy in Japan, it is important to assess the association between obesity and cardiovascular risk factors. Therefore, we conducted anthropometric measures of obesity and investigated the association of obesity with cardiovascular risk factors such as hypertension, diabetes, and dyslipidemia among community-dwelling men (N=85) and women (N=173) aged 40 years and older. Height, weight, and waist circumference (WC) were measured, and body ... Read More »
» Published in J Physiol Anthropol. 2006 Nov;25(6):371-5.

22. Obesity and cardiovascular risk factors among men and women aged 40 years and older in a rural area of Japan.
Match Strength: 6.312

Obesity is one of the most common health problems, and is recognized worldwide as an "escalating epidemic." For the establishment of an obesity-prevention strategy in Japan, it is important to assess the association between obesity and cardiovascular risk factors. Therefore, we conducted anthropometric measures of obesity and investigated the association of obesity with cardiovascular risk factors such as hypertension, diabetes, and dyslipidemia among community-dwelling men (N=85) and women (N=173) aged 40 years and older. Height, weight, and waist circumference (WC) were measured, and body ... Read More »
» Published in J Physiol Anthropol. 2006 Nov;25(6):371-5.

23. Obesity hypertension.
Match Strength: 6.278

The association between obesity and hypertension is well recognized. However, the exact mechanisms whereby obesity causes hypertension are complex and multifactorial. The current article summarizes some of the known mechanisms responsible for obesity hypertension ... Read More »
» Published in Am J Hypertens. 2002 Feb;15(2 Pt 2):50S-52S.

24. Cardiovascular complications of obesity in adolescents.
Match Strength: 6.252

Obesity is an increasingly important worldwide health problem, representing the major risk factor for coronary heart disease. The increase in the prevalence of obesity, particularly among younger age groups, is likely to have long-term implications for cardiovascular disease (CVD) in the years to come, especially at a young age. Obesity plays a central role in the insulin resistance (IR) syndrome and increases the risk of atherosclerotic CVD. The present review will examine the relationships among cardiovascular risk (CVR) factors during the childhood-adolescence-adulthood transition. In fact, ... Read More »
» Published in J Endocrinol Invest. 2007 Jan;30(1):70-80.

25. Diseases associated with childhood obesity.
Match Strength: 6.243

OBJECTIVE: Radiologists can play an active role in children's health by increasing awareness of diseases associated with obesity. This article reviews key imaging findings in obesity-related diseases, current issues in imaging obese children, and treatment strategies. CONCLUSION: There has been a well-documented pediatric obesity epidemic and a dramatic increase in clinical diseases associated with it. These serious health consequences affect nearly every organ system. Despite the increasing prevalence of obesity and the associated health hazards, pediatric obesity as a diagnosis is often ... Read More »
» Published in AJR Am J Roentgenol. 2007 Apr;188(4):1118-30.

26. Finally: Best Practices Available for Obesity
Match Strength: 6.238

The National Heart, Lung, and Blood Institute's new obesity guidelines urge providers to treat obesity as a chronic disease. The guidelines address fen/phen and other drugs as well as a whole host of issues that should be considered in assessing obesity and managing weight. A program to change lifestyle habits requires behavior modification and frequent contact between physicians and patients ... Read More »
» Published in Healthc Benchmarks. 1998 Sep;5(9):141-4.

27. Increasing trends in incidence of overweight and obesity over 5 decades.
Match Strength: 6.236

PURPOSE: We evaluated trends in the incidence of overweight and obesity over the past 50 years. METHODS: We evaluated trends in the incidence of overweight (25< or =body mass index [BMI] <30 kg/m2), obesity (BMI > or =30 kg/m2) and stage 2 obesity (BMI > or =35 kg/m2) from 1950 to 2000 in Framingham Study participants (n=6798, 54% women). Individuals aged 40-55 years who attended 2 examinations 8 years apart in each decade were eligible. RESULTS: The incidences of overweight, obesity, and stage 2 obesity increased across the decades in both sexes (P for trend <.001). For men, ... Read More »
» Published in Am J Med. 2007 Mar;120(3):242-50.

28. Could a virus contribute to weight gain?
Match Strength: 6.234

Objective:Obesity is a serious public health problem associated with increased morbidity and mortality. Although the causes for obesity are unclear, it seems that environmental, genetic, neural and endocrine factors contribute to its development. However, the rapid global spread of obesity resembles epidemiologically the spread of an infectious disease. Thus far, little consideration has been given to the possibility that the epidemic of obesity could be due to an infectious agent. Seven viruses and a scrapie agent have been implicated in obesity.Design:This review evaluates the infectious ... Read More »
» Published in Int J Obes (Lond). 2007 Apr 10;

29. Obesity: Epidemiology and Clinical Aspects
Match Strength: 6.234

At the beginning of the 21st Century, obesity has become the leading metabolic disease in the World. So much so, that the World Health Organisation refers to obesity as the global epidemic. In fact, obesity is a common disease affecting not only affluent societies but also developing countries. Currently 300 million people can be considered as obese and, due to the rising trend in obesity prevalence, this figure could double by year 2025 if no action is taken against this threat. In terms of health impairment, the importance of obesity lies in the fact that, besides being a disease in itself, ... Read More »
» Published in Best Pract Res Clin Gastroenterol. 2004 Dec;18(6):1125-46.

30. Obesity in carnivores.
Match Strength: 6.222

Obesity is the common nutritional disorder affecting more and more animals every year. Obese individuals have altered metabolism and disorders of many organs. Obesity may develop as a result of specific genetic, metabolic, nervous and environmental factors. Dietary management of obesity requires addressing the underlying metabolism of the animal, normalizing the glucose level and proper treatment of diabetes, which is usually associated with obesity. Novel nutrients like leptin, chromium, carnitine and starch added to the diet as well as new approaches in the obesity therapy are very important ... Read More »
» Published in Pol J Vet Sci. 2005;8(4):329-35.

31. Cardiovascular Consequences of Obesity
Match Strength: 6.213

Obesity is common in populations that are overnourished and can become a significant public health problem. Obesity predisposes to non-insulin dependent diabetes mellitus, hypertension, dyslipidemia, cholelithiasis, some malignancies and osteoarthritis. These consequences that most directly affect the cardiovascular system are dyslipidemia and hypertension. Nations in which obesity is rare should learn from the experience of the countries where it is prevalent, that prevention of obesity is a public health measure rather than weight reduction ... Read More »
» Published in Chin Med J (Engl). 1992 May;105(5):360-3.

32. Treatment of obesity in the primary care setting: are we there yet?
Match Strength: 6.210

Obesity is a significant public health issue in the US constituting an independent risk factor for morbidity and mortality as well as complicating the management of other medical conditions. Yet, traditionally most physicians receive little training in evidence-based obesity interventions. Previous literature suggests many physicians believe they do not have effective tools to address obesity and/or that obesity management is not within their scope of practice. Given the new emphasis from NIH and AAFP urging physicians to conceptualize and treat obesity as a chronic medical condition, we ... Read More »
» Published in Eat Disord. 2007 Mar-Apr;15(2):135-43.

33. Promising new causal explanations for obesity and obesity-related diseases.
Match Strength: 6.184

Current explanations for obesity center around a predisposition in genotype and phenotype, possibly triggered by an inflammatory process or event, and exacerbated by environmental and psychological factors. It is likely that a variety of physiologic factors may act in combination to produce clinical obesity. Leptin resistance may be an important neurochemical cause of obesity; elevated leptin levels have been correlated with weight gain over extended time periods. Genetic studies support the postulate that a gene originating with our cave-dwelling ancestors, critical to survival when food was ... Read More »
» Published in Biol Res Nurs. 2007 Jan;8(3):223-33.

34. Clinical Guidelines for Diagnosis and Management of Obesity in the Czech Republic
Match Strength: 6.154

Guidelines for the management of obesity include recommendation about diet, exercise, behavioral modification, drug therapy and bariatric surgery in the comprehensive management of an obese patient. It is emphasized that the treatment of obesity should be individually tailored according to the age of the patient, degree and phase of obesity, body fat distribution and an expression of risk factors and comorbidities. The new realistic goals in obesity management do not focus on the weight loss per se but mainly on the risk factors reduction which accompanies even modest weight loss. The system ... Read More »
» Published in Sb Lek. 1998;99(3):235-50.

35. Obesity in childhood and adolescence: evidence based clinical and public health perspectives.
Match Strength: 6.132

A global epidemic of paediatric obesity occurred in recent years, and prevalence of obesity is continuing to rise. In the developed world obesity is now the most common disease of childhood and adolescence. Paediatric obesity is not a cosmetic issue, being associated with a significant burden of ill health both for obese children and for adults who were obese as children. Health professionals tend to underestimate the impact of paediatric obesity, and lack the skills, knowledge, and time to treat it effectively. This short review aims to summarise recent systematic reviews on the origins, ... Read More »
» Published in Postgrad Med J. 2006 Jul;82(969):429-37.

36. Is It Possible to Prevent Obesity?
Match Strength: 6.130

No-one is immune to obesity, but those with a family history of obesity, or those who have in the past lost weight, are particularly liable to excessive weight gain. There is no useful way of identifying that portion of the population which is at particularly high risk of obesity so that preventive measures can be focussed on that subgroup. Prevention of obesity therefore requires early detection and treatment of excessive weight gain. For various reasons the age range 5-12 years is particularly advantageous for correcting obesity in children, since normal weight-for-height can be achieved ... Read More »
» Published in Infusionstherapie. 1990 Feb;17(1):28-31.

37. Medical management of obesity.
Match Strength: 6.122

Primary intervention in the medical management of obesity is dietary restriction and physical activity with additional benefit gained from behaviour therapy. Subsequent use of anti-obesity drugs depends on unsatisfactory weight loss in a patient at medical risk from obesity. All treatment programmes must include long-term follow up. Publication Types: ... Read More »
» Published in Br J Hosp Med (Lond). 2007 Feb;68(2):89-93.

38. Definitions and demographics of obesity: diagnosis and risk factors.
Match Strength: 6.106

The incidence of obesity is increasing yearly among adults and children in the United States and worldwide. Although there is a significant genetic component to obesity, the genome has not changed. The epidemic is caused by an increase in dietary fat and caloric input and a decrease in physical activity. There are significant racial, ethnic, and sociologic differences in all categories of obesity as well as in the disease burden it brings. The effects of the obesity epidemic are considerable, second only to tobacco use in the expenditure of health care dollars and as a cause of premature ... Read More »
» Published in Anesthesiol Clin North America. 2005 Sep;23(3):397-403, v.

39. Obesity and selected co-morbidities in an urban Palestinian population.
Match Strength: 6.103

OBJECTIVE: To assess the prevalence of obesity and central obesity in an urban Palestinian population and their associations with selected co-morbidities, including diabetes, hypertension and dyslipidaemia. DESIGN: A population-based cross-sectional survey in an urban Palestinian community. SUBJECTS: Men and women aged 30-65 y residing in the urban community, excluding pregnant women. MEASUREMENTS: According to WHO guidelines, obesity for men and women was defined as BMI> or =30 kg x m(-2), while pre-obesity was defined as BMI 25-29.9 kg x m(-2). Central obesity was defined as a waist-to ... Read More »
» Published in Int J Obes Relat Metab Disord. 2001 Nov;25(11):1736-40.

40. Obesity and Coronary Heart Disease
Match Strength: 6.102

Obesity is commonly cited as a risk factor for the development of coronary heart disease (CHD). Epidemiologic studies tend to support this contention, particularly those focusing on patients with central obesity. Such studies however, are imprecise and prone to misclassification bias. Angiographic and post mortem studies have demonstrated little or no correlation of total fat mass and coronary atherosclerosis except in those with abdominal obesity. There is a strong association of obesity, particularly central obesity, and traditional risk factors for CHD such as hypertension, type II diabetes ... Read More »
» Published in Am J Med Sci. 2001 Apr;321(4):215-24.

41. Obesity and Diabetes in African American Women
Match Strength: 6.094

Obesity has reached near epidemic proportions in the United States. The prevalence of obesity is high among African Americans, particularly African American women. The risk of diabetes is significantly related to obesity. The risks of morbidity and mortality associated with diabetes poses serious problems for the African American community. It is vital that nurses be at the forefront in initiating research studies, developing strategies for use in practice and providing education to the public about the potentially deadly consequences of obesity ... Read More »
» Published in ABNF J. 2003 May-Jun;14(3):66-8.

42. North American Society for the Study of Obesity--annual meeting. Emerging perspectives on obesity. 14-18 November 1999, Charleston, SC, USA.
Match Strength: 6.079

This meeting focused on the latest research and clinical developments in the field of obesity. Record high attendance emphasized the recognition of obesity as an emerging and exciting area of study, both from the basic science aspects as well as from a clinical standpoint. While presentations at the meeting emphasized the importance of retaining our current public health message of low-fat diets and exercise for obesity prevention and management, several novel approaches (both behavioral and pharmaceutical) were also presented. In animal models, the presentation of data on a novel obesity ... Read More »
» Published in IDrugs. 2000 Feb;3(2):164-6.

43. Obesity management.
Match Strength: 6.053

Because obesity is associated with an increased risk of multiple health problems, it is important for gastroenterologists and all health care providers routinely to identify, evaluate, and treat patients for obesity in the course of daily practice. Therapy for obesity always begins with lifestyle management and may include pharmacotherapy or surgery. Setting an initial weight loss goal of 10% over 6 months is a realistic target, followed by long-term management ... Read More »
» Published in Gastroenterol Clin North Am. 2007 Mar;36(1):191-210, viii.

44. Obesity: a problem of darwinian proportions?
Match Strength: 6.049

Obesity has been described as an abnormality arising from the evolution of man, who becomes fat during the time of perpetual plenty. From the perspective of "Darwinian Medicine," if famine is avoided, obesity will prevail. Problems regarding obesity arise within many disciplines, including socioeconomic environments, the educational system, science, law, and government. This article will discuss various ethical aspects of several disciplines regarding obesity, with a focus on scientific inquiry. We will discuss this within the categories: (1) chronic kidney disease predialysis, (2) dialysis, ... Read More »
» Published in Adv Chronic Kidney Dis. 2006 Oct;13(4):428-32.

45. The Effect of Obesity on Chronic Respiratory Diseases: Pathophysiology and Therapeutic Strategies
Match Strength: 6.048

Sedentary lifestyles and increased pollution brought about by industrialization pose major challenges to the prevention of both obesity and chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD), asthma, obstructive sleep apnea and obesity hypoventilation syndrome. Obesity has emerged as an important risk factor for these respiratory diseases, and in many instances weight loss is associated with important symptomatic improvement. Moreover, obesity may influence the development and presentation of these diseases. In this article, we review the current understanding of ... Read More »
» Published in CMAJ. 2006 Apr 25;174(9):1293-9.

46. Epidemiology, Morbidity, And Treatment Of Overweight And Obesity
Match Strength: 6.023

Although still considered more of a cosmetic problem by both the general public and some areas of the medical community, overweight and obesity have reached epidemic proportions worldwide. Overweight and obesity have not only a significant psychological impact but also result in an increased risk for development of numerous chronic and sometimes fatal diseases. The morbidity from obesity-associated disorders increases with higher body mass index and begins within the normal weight range. The costs (direct and indirect) associated with treating obesity and its comorbid conditions are notable ... Read More »
» Published in J Clin Psychiatry. 2001;62 Suppl 23:13-22.

47. Obesity and Type-2 Diabetes in the Elderly
Match Strength: 6.016

Type-2 diabetes is common in the elderly and when compounded by obesity presents a major challenge for the physician. Obesity plays a central role in the aetiology and pathogenesis of type-2 diabetes. Body weight is determined by an interaction between genetic, environmental and psychosocial factors acting through the physiological mediators of energy intake and expenditure. Obesity is thought to predispose to type-2 diabetes primarily by causing insulin resistance. Education and changes in lifestyle remain the key issues in obesity management. Anti-obesity drugs may delay the onset of ... Read More »
» Published in Gerontology. 2003 May-Jun;49(3):137-45.

48. Obesity: Prevalence, Causes, Health Risks and Treatment
Match Strength: 6.013

This article reviews the latest research on the prevalence, causes, health risks and treatment of obesity. The attitudes and beliefs of nurses about obesity are also examined. Obesity is an increasing health problem. Contributing factors to the development of obesity include a genetic disposition to gain weight, a high fat diet and a lowered energy expenditure. Obesity is a risk factor for a number of chronic diseases and therefore weight loss is usually advisable. Treatment of obesity can take several approaches and requires a change in dietary intake. Changing dietary habits to reduce the ... Read More »
» Published in Br J Nurs. 1997 Nov 13-26;6(20):1181-5.

49. Obesity-related cardiovascular disease: implications of obstructive sleep apnea.
Match Strength: 6.007

Obesity and obstructive sleep apnea (OSA) often coexist. OSA has been linked to cardiovascular disease. Thus, OSA may contribute to the cardiovascular consequences of obesity. In this review, we explore clinical and pathophysiological interactions between obesity, cardiovascular disease and OSA. We discuss the mechanisms whereby OSA may contribute to hypertension, atherosclerosis, insulin resistance and atrial fibrillation associated with obesity, and emphasize the potential implications for understanding why only a subgroup of obese patients develop cardiovascular disease. Identification of ... Read More »
» Published in Diabetes Obes Metab. 2006 May;8(3):250-60.

50. The Effect of Obesity Surgery on Obesity Comorbidity
Match Strength: 6.005

Obesity is epidemic in the modern world. It is becoming increasingly clear that obesity is a major cause of cardiovascular disease, diabetes, and renal disease, as well as a host of other comorbidities. There are at present no generally effective long-term medical therapies for obesity. Surgical therapy for morbid obesity is not only effective in producing long-term weight loss but is also effective in ameliorating or resolving several of the most significant complications of obesity, including diabetes, hypertension, dyslipidemia, sleep apnea, gastroesophageal reflux disease, degenerative ... Read More »
» Published in Am J Med Sci. 2006 Apr;331(4):183-93.

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