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Mineral
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1. Thirty-five percent carbamide peroxide application causes in vitro demineralization of enamel.
Match Strength: 5.893

OBJECTIVES: The objective of this in vitro study was to investigate whether a high concentration 'in-office' bleaching agent affected the mineral content of enamel and dentin. METHODS: A commercially available 35% carbamide peroxide bleaching agent was applied for 2h to sectioned teeth (n=11). Specimens were then immersed in artificial saliva at 37 degrees C for a further 24h to simulate the oral environment. Tomographic images of these sections were obtained (micro-CT 80, Scanco, Switzerland) prior to and post-bleach application. Eight three-dimensional regions of interest (ROI), starting ... Read More »
» Published in Dent Mater. 2006 Sep 22;

2. Comparative evaluation of the peri-implant bone tissue mineral density around unloaded titanium dental implants.
Match Strength: 5.592

OBJECTIVE: The mechanical properties of bone are greatly influenced by the percentages of organic and mineral constituents. Nevertheless, the information about the mineral content on a microscopic scale in peri-implant bone is scarce. The aim of this work was to analyze the bone mineral density of peri-implant bone under different techniques. DESIGN: Five unloaded titanium dental implants with a micro-structured surface (three XiVE plus and two Frialit 2, DENTSPLY-Friadent, Mannheim, Germany) were retrieved from the mandible of five patients after a 6-month period. scanning electron microscopy ... Read More »
» Published in J Dent. 2007 Jan;35(1):84-92. Epub 2006 Sep 18.

3. Composition of calcifications in children with juvenile dermatomyositis: association with chronic cutaneous inflammation.
Match Strength: 5.244

OBJECTIVE: Calcific deposits develop in 20-40% of children with juvenile dermatomyositis (juvenile DM), contributing to disease morbidity and mortality. This study was undertaken to define the structure and composition of these deposits and to characterize their association with chronic inflammation. METHODS: We examined calcific deposits from 5 children with juvenile DM (2 boys and 3 girls). The crystal structure and mineral content of the deposits was analyzed by x-ray diffraction, Fourier transform infrared spectroscopy, and imaging. The protein content of the deposits, following ... Read More »
» Published in Arthritis Rheum. 2006 Oct;54(10):3345-50.

4. Effects of calcium supplementation on bone density in healthy children: meta-analysis of randomised controlled trials.
Match Strength: 4.987

OBJECTIVES: To assess the effectiveness of calcium supplementation for improving bone mineral density in healthy children and to determine if any effect is modified by other factors and persists after supplementation stops. DESIGN: Meta-analysis. DATA SOURCES: Electronic bibliographic databases, hand searching of conference proceedings, and contacting authors for unpublished data. REVIEW METHODS: We included randomised placebo controlled trials of calcium supplementation in healthy children that lasted at least three months and had bone outcomes measured after at least six months of follow-up. ... Read More »
» Published in BMJ. 2006 Oct 14;333(7572):775. Epub 2006 Sep 15. Comment in: BMJ. 2006 Oct 14;333(7572):763-4.

5. Lumbar ontogenetic allometry and dimorphism in humans. A case for comparison between interspecific and intraspecific scaling.
Match Strength: 4.868

The ontogenetic allometry of the lumbar region of 1913 humans (1228 females and 685 males), ranging from newborn to 21-year-old individuals, was studied by means of length, width, projected surface area and bone mineral density of the segment L2 - L4, obtained by dual X-ray absorptiometry (DXA). All these parameters were regressed to body mass and height of the individuals, considered alternatively as the independent variable. Firstly, we addressed the comparison between the results obtained on both sexes in order to elucidate whether ontogenetic differences existed. Length of the segments ... Read More »
» Published in Eur J Morphol. 2005 Oct-Dec;42(4-5):185-92.

6. Bone mineral density in long-term Chinese heart transplant recipients: a cross-sectional study.
Match Strength: 4.600

Osteoporosis, which usually peaks during 6 to 12 months after transplantation, remains an important concern after heart transplantation. Immunosuppressants contribute to this phenomenon. Glucocorticoids are well documented to cause bone loss, but the role of cyclosporine (CsA) remains controversial, especially among long-term recipients on low doses of steroid. We herein report a cross-sectional study of bone mineral density (BMD) among long-term Chinese heart transplant recipients. We enrolled 41 patients of mean age 50.15 +/- 13.58 years with a mean follow-up of 57.02 months. Lumbar spine ... Read More »
» Published in Transplant Proc. 2006 Sep;38(7):2141-4.

7. Bone density changes in women who receive thromboprophylaxis in pregnancy.
Match Strength: 4.408

OBJECTIVE: The purpose of this study was to compare unfractionated heparin therapy to the low molecular weight heparin, enoxaparin sodium, and their effects on bone mineral density over the course of pregnancy. STUDY DESIGN: Pregnant patients whose condition required thromboprophylaxis were recruited in this prospective randomized controlled trial and were assigned to receive either unfractionated heparin therapy or low molecular weight heparin therapy. Bone mineral density was measured by dual energy x-ray absorptiometry at the proximal femur on enrollment and again shortly after delivery. ... Read More »
» Published in Am J Obstet Gynecol. 2006 Oct;195(4):1109-13.

8. Effect of underground working on vitamin D levels and bone mineral densities in coal miners: a controlled study.
Match Strength: 4.080

The aim of this study was to determine the effect of underground working on 25-hydroxyvitamin D (25-OHD) levels and bone mineral density (BMD) values in coal miners. Fifty coal miners working underground and 50 surface workers as controls, matched for age and body mass index, from Zonguldak, Turkey, were recruited to the study. Levels of 25-OHD, biochemical bone markers, and lumbar spine and femur BMD values were measured in all study participants. Lumbar spine and femur BMD values were significantly higher in underground workers compared with surface workers, but there was no significant ... Read More »
» Published in J Int Med Res. 2006 Jul-Aug;34(4):362-6.

9. Bone mineral density loss and recovery during 48 months in first-time users of depot medroxyprogesterone acetate.
Match Strength: 3.837

OBJECTIVE: To compare changes in bone mineral density (BMD) during 48 months between first-time depot medroxyprogesterone acetate (MPA) users, during use and after discontinuation, to controls. DESIGN: Longitudinal study. SETTING: Academic community. PATIENT(S): Women 18-35 years, newly initiating depot MPA (n = 178) and controls (n = 145) not using hormonal contraception. MAIN OUTCOME MEASURE(S): The BMD of the hip and spine, measured at 3-month intervals, by dual energy roentgen absorptiometry. RESULTS: Hip and spine BMD declined during 48 months of depot MPA use by 7.7% +/- 0.11% (mean +/- ... Read More »
» Published in Fertil Steril. 2006 Nov;86(5):1466-74. Epub 2006 Sep 25.

10. Proximal humeral fractures: regional differences in bone mineral density of the humeral head affect the fixation strength of cancellous screws.
Match Strength: 3.785

The purpose of this study was to investigate the 3-dimensional trabecular bone mineral density (BMD) in the humeral head and determine the effects of trabecular BMD on the pullout strength of cancellous screws. Five regions of interest (ROIs) were defined in the humeral head (superior- anterior, superior-posterior, central, inferior-anterior, and inferior-posterior). The trabecular BMD of each ROI was determined by use of peripheral quantitative computed tomography. Cancellous screws were inserted in each ROI and cyclically loaded. The superior-anterior ROI had a lower trabecular BMD than all ... Read More »
» Published in J Shoulder Elbow Surg. 2006 Sep-Oct;15(5):620-4. Epub 2006 Aug 7.

11. Collagen scaffolds reinforced with biomimetic composite nano-sized carbonate-substituted hydroxyapatite crystals and shaped by rapid prototyping to contain internal microchannels.
Match Strength: 3.735

The next generation of tissue engineering scaffolds will be made to accommodate blood vessels and nutrient channels to support cell survival deep in the interior of the scaffolds. To this end, we have developed a method that incorporates microchannels to permit the flow of nutrient-rich media through collagen-based scaffolds. The scaffold matrix comprises nano-sized carbonate-substituted hydroxyapatite (HA) crystals internally precipitated in collagen fibers. The scaffold therefore mimics many of the features found in bone. A biomimetic precipitation technique is used whereby a collagen ... Read More »
» Published in Tissue Eng. 2006 Sep;12(9):2479-87.

12. Selective estrogen receptor modulators to prevent treatment-related osteoporosis.
Match Strength: 3.715

The intended therapeutic effect of gonadotropin-releasing hormone (GnRH) agonists is hypogonadism, which is a leading cause of osteoporosis in men. Consistent with this observation, GnRH agonists decrease bone mineral density and increase fracture risk in men with prostate cancer. GnRH agonists markedly decrease serum levels of both testosterone and estrogen. Estrogens play a central role in homeostasis of the normal male skeleton, and the available evidence suggests that estrogen deficiency rather than testosterone deficiency accounts for the adverse skeletal effects of GnRH agonists. The ... Read More »
» Published in Rev Urol. 2005;7 Suppl 3:S30-5.

13. Associations of iron status with dietary and other factors in 6-year-old children.
Match Strength: 3.680

Objective:To investigate the associations of iron status at 6 years of age with dietary and other factors.Design:In a cross-sectional study, children's dietary intakes (3-day weighed food record) were recorded, body size was measured and blood samples were taken near their sixth birthday.Subjects:A sample of 188 children, from two previous studies (cohorts 1 and 2), was contacted, and 139 (74%) agreed to participate.Results:Multiple regression analyses with dietary and other factors showed that meat and fish consumption, multivitamin/mineral supplement intake (both positively) and cow's milk ... Read More »
» Published in Eur J Clin Nutr. 2006 Sep 20;

14. Effect of ionophore supplementation on the incidence of Escherichia coli O157:H7 and Salmonella and antimicrobial susceptibility of fecal coliforms in Stocker cattle.
Match Strength: 3.542

To examine the effect of ionophore supplementation on fecal shedding of Escherichia coli O157:H7 and Salmonella, crossbred beef calves (n=113; mean body weight [BW], 243 kg) were fed a mineral supplement with ionophore (1.76 g lasalocid/kg) for 61 days (d). Control calves received an identical mineral supplement without lasalocid. Calves were pastured on fescue/bermudagrass paddocks and supplemented with a corn/wheat midds/soybean meal supplement (1.5% of BW/d). Upon arrival, cattle were fed a commercial receiving ration containing 1 g chlorotetracycline/kg for 10 d. Sick calves were ... Read More »
» Published in Foodborne Pathog Dis. 2006 Fall;3(3):284-91.

15. Occupational Exposure to Mineral Fibres: Analysis of Results Stored on Colchic Database.
Match Strength: 3.531

The aim of this paper is to present fibre exposure data recorded on the COLCHIC database. This database consolidates all occupational exposure data collected in French companies by the Caisses Regionales d'Assurance Maladie (regional health insurance funds, CRAM) and the Institut National de Recherche et de Securite (national institute for research and safety, INRS). A total of 8029 concentration results, expressed in number of fibres measured by phase-contrast optical microscopy, are available for exposure to asbestos fibres, ceramic fibres and man-made mineral fibres other than ceramic ... Read More »
» Published in Ann Occup Hyg. 2006 Sep 19;

16. Increase of bone volume by a nanosecond pulsed laser irradiation is caused by a decreased osteoclast number and an activated osteoblasts.
Match Strength: 3.492

The biostimulatory effects of laser irradiation focus not only in the field of soft tissue but also bone formation. Studies have shown that the light of a nanosecond pulsed laser which has a high peak power can produce stress waves in tissue. We have hypothesized that nanosecond pulsed laser irradiation stimulates bone formation. Our aim was to clarify the mechanism of increased bone volume by nanosecond pulsed laser irradiation. Rat femur was irradiated with a Q-switched Nd:YAG laser, which has a wavelength of 1064 nm. The quantification of trabecular architecture using three-dimensional ... Read More »
» Published in Bone. 2007 Jan;40(1):140-8. Epub 2006 Sep 15.

17. Non-invasive therapy to reduce the body burden of aluminium in Alzheimer's disease.
Match Strength: 3.395

There are unexplained links between human exposure to aluminium and the incidence, progression and aetiology of Alzheimer's disease. The null hypothesis which underlies any link is that there would be no Alzheimer's disease in the effective absence of a body burden of aluminium. To test this the latter would have to be reduced to and retained at a level that was commensurate with an Alzheimer's disease-free population. In the absence of recent human interference in the biogeochemical cycle of aluminium the reaction of silicic acid with aluminium has acted as a geochemical control of the ... Read More »
» Published in J Alzheimers Dis. 2006 Sep;10(1):17-24; discussion 29-31.

18. Estrogen rapidly modulates mustard oil-induced visceral hypersensitivity in conscious female rats: A role of CREB phosphorylation in spinal dorsal horn neurons.
Match Strength: 3.219

This study investigated the effect of sex hormones on mustard oil (MO)-induced visceral hypersensitivity in female rats and analyzed possible involved signaling pathways. Female rats, either intact or ovariectomized (OVX), were prepared for abdominal muscle electromyography in response to colorectal distension after intracolonic instillation of MO. The effect of MO intracolonic sensitization was evaluated in intact rats, OVX rats, and OVX rats pretreated with a single injection of 17beta-estradiol (E), progesterone (P), E+P, or vehicle. cAMP-responsive element-binding protein (CREB) and ... Read More »
» Published in Am J Physiol Gastrointest Liver Physiol. 2007 Jan;292(1):G438-46. Epub 2006 Sep 14.

19. Adrenal incidentaloma (adrenaloma).
Match Strength: 3.208

The management of adrenalomas should include the following:1. A detailed history and physical examination to detect subtle evidence of hormonal hypersecretion or the possibility of metastatic carcinoma.2. Hormonal studies:* Short dexamethasone suppression test (2 mg of dexamethasone) followed by a high-dose dexamethasone suppression test (8 mg), CRH assay and analysis of the diurnal cortisol rhythm if serum cortisol value post dexamethasone is greater than 3microg/dL* 24-hour (or spot) urinary catecholamine metabolites (metanephrine and normetanephrine)* In the hypertensive or normotensive ... Read More »
» Published in Hormones (Athens). 2003 Jan-Mar;2(1):12-21.

20. Effects of the long-term use of depot medroxyprogesterone acetate as hormonal contraceptive on bone mineral density and biochemical markers of bone remodeling.
Match Strength: 3.199

PURPOSE AND METHOD: Our objective is to evaluate the effects of the long-term use of depot medroxyprogesterone acetate (DMPA) as a method of contraception on bone mineral density (BMD) and bone remodeling. Forty women (21-44 years old) who used DMPA for contraception for <1, 1-2 and >5 years, in addition to 20 age-matched healthy women (nonusers), participated in this study. Lumbar spine BMD (LS-BMD) was measured by dual-energy X-ray absorptionmetry. Serum osteocalcin (OC), a bone formation marker, was measured by enzyme amplification sorbent immunoassay. Urinary deoxypyridinoline (DPD), ... Read More »
» Published in Contraception. 2006 Oct;74(4):297-302. Epub 2006 Jun 16.

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