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 << Prev 20  Showing 1 to 20 of 71 Matches Next 20 >>



1. Remaking the future: contemplating a life with chronic widespread pain.
Match Strength: 3.599

OBJECTIVES: This paper reports findings from a larger study that aimed to explore how people with chronic widespread pain experience, understand and make meaning of their 'condition', and attempt to influence or exert control over their pain. This included an exploration of sufferers' understanding of the past and future as well as of their present situation. METHODS: A combination of data generation methods was used, including lifegrid interviews, diaries and diary interviews, with eight people with chronic widespread pain. Five family members also participated in interviews. Analytical ... Read More »
» Published in Chronic Illn. 2006 Sep;2(3):209-18.

2. Towards education-fair dementia screening.
Match Strength: 3.420

The study by Rowland et al. (2006) has shown that the six-item Rowland Universal Dementia Assessment Scale (RUDAS) is as accurate as the MMSE in identifying dementia. A high positive likelihood ratio of RUDAS makes it useful for ruling-in dementia in cases where the disorder is suspected ... Read More »
» Published in Int Psychogeriatr. 2006 Sep 14;:1-2

3. Immunopathology of RSV infection: prospects for developing vaccines without this complication.
Match Strength: 3.041

Respiratory syncytial virus is the most important cause of lower respiratory tract infection in infants and young children. RSV clinical disease varies from rhinitis and otitis media to bronchiolitis and pneumonia. An increased incidence of asthma later in life has been associated with the more severe lower respiratory tract infections. Despite its importance as a pathogen, there is no licensed vaccine against RSV. This is due to a number of factors complicating the development of an effective and safe vaccine. The immunity to natural RSV infection is incomplete as re-infections occur in all ... Read More »
» Published in Rev Med Virol. 2007 Jan-Feb;17(1):5-34.

4. Challenges to the generality of WBE theory.
Match Strength: 2.997

The West, Brown and Enquist (WBE) theory has attracted great interest because it makes general predictions about scaling of ecological processes with body size. Recent research by Muller-Landau and co-workers challenges the generality of this theory by showing that demographic processes in natural forests do not scale in the way that the theory predicts. For WBE theory to be relevant to plant community dynamics, more complex models are required to deal with the influences of competition for light, nutrient supply and disturbance experienced by such communities ... Read More »
» Published in Trends Ecol Evol. 2006 Nov;21(11):593-6. Epub 2006 Sep 20.

5. A Re-analysis of Our Current Understanding of Isthmus-Dependent Atrial Flutter: Some Gaps, Some Hypotheses.
Match Strength: 2.790

The macro-reentrant circuit of isthmus-dependent atrial flutter (AFL) is located in the right atrium around the tricuspid annulus. High acute success and low recurrence rate makes isthmus ablation a definitive therapy for patients with only AFL. However, a review of the literature suggests that, different aspects of this macro-reentrant circuit are still not entirely understood, while new information continues to emerge. The aim of this article is to discuss some gaps in our "complete" understanding of isthmus-dependent AFL. Few hypotheses have been stated which are open to investigation ... Read More »
» Published in Indian Pacing Electrophysiol J. 2001 Oct 1;1(1):23-31.

6. Hairy cell leukemia: diagnostic pathology.
Match Strength: 2.719

The pathology of HCL has been reviewed with a focus on the diagnostic hematopathology of this rare, but fascinating, disease. The discrimination of HCL from other B-cell lymphoproliferations, particularly HCL-V and SMZL, has been emphasized. The unique responsiveness of HCL to 2-CdA and other chemotherapeutic agents makes this distinction critical. Fortunately, HCL has consistent cytologic, histologic, cytochemical, and immunologic features that make classification reliable and reproducible. Less straightforward is the differential diagnosis of SMZL and HCL-V, problematic because of the rarity ... Read More »
» Published in Hematol Oncol Clin North Am. 2006 Oct;20(5):1023-49.

7. Small bowel bacterial overgrowth. An underrecognized cause of malnutrition in older adults.
Match Strength: 2.620

Small bowel bacterial overgrowth (SBBO) is an important and under-recognized clinical syndrome in the elderly. It is the most common cause of malabsorption among older adults. Presentation of SBBO syndrome is often occult, which makes it imperative to maintain a high index of suspicion for this disorder. When symptomatic bacterial overgrowth is appropriately identified and treated there can be positive dramatic results. This article discusses the importance of considering a diagnosis of bacterial overgrowth in those predisposed to its development and the mechanisms by which nutrient ... Read More »
» Published in Geriatrics. 2006 Sep;61(9):21-6.

8. The Bonn Agreement Aerial Surveillance programme: Trends in North Sea oil pollution 1986-2004.
Match Strength: 2.553

This paper examines the use of aerial surveillance activities conducted in the North Sea region of Europe since 1986 to assess trends in levels of oil inputs into the marine environment, both across the whole region and within the waters of the different coastal states. It makes use of data collected under the aegis of the 1969 Bonn Agreement through its Annual Reports on Aerial Surveillance and examines developments in surveillance methods and technology which have led to improvements in the detection of oil spills, even during the hours of darkness. The paper then examines country specific ... Read More »
» Published in Mar Pollut Bull. 2007 Feb;54(2):149-63. Epub 2006 Sep 18.

9. Shape-coded silica nanotubes for biosensing.
Match Strength: 2.550

Shape-coded silica nanotubes (SNTs) were fabricated on the basis of template synthesis as a new dispersible microarray system. The template synthesis of shape-coded SNTs begins with the fabrication of a porous alumina film that has well-defined cylindrical pores with two or more different diameter segments by multistep anodization of an aluminum substrate. Then, SNTs were fabricated with a surface sol-gel method that can control the wall thickness of SNTs on the single-nanometer level. Attractively, the difference in optical reflectance between the segmented parts of individual silica nanotube ... Read More »
» Published in Langmuir. 2006 Sep 26;22(20):8263-5.

10. Home-based palliative care for children: the case for funding.
Match Strength: 2.525

Paediatric palliative care services have grown up in response to local needs with the result that provision is patchy and in some areas non-existent. Funding for existing services comes from a variety of sources and in the case of teams funded in 2003 from The New Opportunities Fund, there is uncertainty about future provision as funding streams come to an end. This article illustrates how home-based palliative care achieves the objectives of the NHS Plan (DH 2000a) and makes the case for the continuation of paediatric palliative care teams already established through New Opportunities Fund ... Read More »
» Published in Paediatr Nurs. 2006 Sep;18(7):20-4.

11. Protection from autoimmunity by DNA vaccination against T-cell receptor.
Match Strength: 2.503

T-lymphocytes are essential participants of adaptive immunity, essential for cellular and humoral recognition of foreign antigens. In pathogenic situations T cells may, however, also recognize self-antigens, causing detrimental autoimmune responses that ultimately lead to autoimmune disease. Experimental autoimmune encephalomyelitis (EAE) is a murine model for the autoimmune disease multiple sclerosis, in which T cells invade the central nervous system and destroy the myelin sheath around neuronal axon fibers. In some EAE systems, the sequence of the alpha- or beta-chains of the pathogenic T ... Read More »
» Published in Methods Mol Med. 2006;127:269-80.

12. Overactive bladder: The importance of new guidance.
Match Strength: 2.485

Overactive bladder (OAB) affects an estimated 49 million people in Europe, but only a minority receive appropriate treatment. Others are bothered by unacceptable levels of symptoms that severely impair their quality of life and represent a significant financial burden to themselves and to their healthcare providers. Recently updated guidelines from the International Consultation on Incontinence (ICI) and the European Association of Urology (EAU) take account of important new developments in the management of bladder problems in both primary and secondary care. However, local implementation of ... Read More »
» Published in Int J Clin Pract. 2006 Oct;60(10):1263-71.

13. Immobilization of bacteria in silica matrices using citric acid in the sol-gel process.
Match Strength: 2.476

The aim of this work was to use citric acid in the sol-gel process to generate an inorganic polymer that allows bacterial survival for long periods of time and to study the influence of different storage temperatures. We compared gram-negative Escherichia coli and gram-positive Staphylococcus aureus, immobilized and preserved at different storage temperatures in silica matrices prepared by the method proposed. Immobilized E. coli and S. aureus in silica matrices were stored in sealed tubes at 20, 4, -20, and -70 degrees C for 4 months during which the number of viable cells was analyzed. ... Read More »
» Published in Appl Microbiol Biotechnol. 2007 Jan;73(5):1059-64. Epub 2006 Sep 15.

14. Sequence determination of lychnin, a type 1 ribosome-inactivating protein from Lychnis chalcedonica seeds.
Match Strength: 2.445

The complete amino acid sequence of lychnin, a type 1 ribosome-inactivating protein (RIP) isolated from Lychnis chalcedonica seeds, has been determined by automated Edman degradation and ESI-QTOF mass spectrometry. Lychnin consists of 234 amino acid residues with a molecular mass of 26 131.14 Da. All amino acid residues involved in the formation of the RIP active site (Tyr69, Tyr119, Glu170, Arg173 and Trp203) are fully conserved. Furthermore, a fast MALDI-TOF experiment showed that two out of three cysteinyl residues (Cys32 and Cys115) form a disulfide bridge, while Cys214 is in the thiol ... Read More »
» Published in Biol Chem. 2006 Sep;387(9):1261-6.

15. Field-flow fractionation of proteins, polysaccharides, synthetic polymers, and supramolecular assemblies.
Match Strength: 2.433

This review summarizes developments and applications of flow and thermal field-flow fractionation (FFF) in the areas of macromolecules and supramolecular assemblies. In the past 10 years, the use of these FFF techniques has extended beyond determining diffusion coefficients, hydrodynamic diameters, and molecular weights of standards. Complex samples as diverse as polysaccharides, prion particles, and block copolymers have been characterized and processes such as aggregation, stability, and infectivity have been monitored. The open channel design used in FFF makes it a gentle separation ... Read More »
» Published in J Sep Sci. 2006 Aug;29(12):1720-32.

16. Politics and health outcomes.
Match Strength: 2.383

The aim of this study was to examine the complex interactions between political traditions, policies, and public health outcomes, and to find out whether different political traditions have been associated with systematic patterns in population health over time. We analysed a number of political, economic, social, and health variables over a 50-year period, in a set of wealthy countries belonging to the Organisation for Economic Co-operation and Development (OECD). Our findings support the hypothesis that the political ideologies of governing parties affect some indicators of population health ... Read More »
» Published in Lancet. 2006 Sep 16;368(9540):1033-7.

17. The use of bacterial minicells to transfer plasmid DNA to eukaryotic cells.
Match Strength: 2.374

The delivery of DNA to mammalian cells is of critical importance to the development of genetic vaccines, gene replacement therapies and gene silencing. For these applications, targeting, effective DNA transfer and vector safety are the major roadblocks in furthering development. In this report, we present a novel DNA delivery vehicle that makes use of protoplasted, achromosomal bacterial minicells. Transfer of plasmid DNA as measured by green fluorescent protein expression was found to occur in as high as 25% of cultured Cos-7 cells when a novel chimeric protein containing the D2-D5 region of ... Read More »
» Published in Cell Microbiol. 2006 Oct;8(10):1624-33.

18. An easy approach to calculating estimated energy requirements.
Match Strength: 2.349

The Dietary Reference Intakes (DRIs) define the daily requirement for energy as the Estimated Energy Requirement (EER). The EER is based on calculations that account for an individual's energy intake, energy expenditure, age, sex, weight, height, and physical activity level. Including physical activity level in the calculations makes determining energy expenditure possible and achieving energy balance a more realistic goal. However, physical activity level is often difficult to measure and accurate assessment of energy expenditure not always possible. We provide an easy way to calculate daily ... Read More »
» Published in Prev Chronic Dis. 2006 Oct;3(4):A129. Epub 2006 Sep 15.

19. Radiation therapy failure in prostate cancer patients: risk factors and methods of detection.
Match Strength: 2.329

Radiation therapy for clinically localized prostatic carcinoma remains one of the mainstays among therapeutic approaches; however, patients continue to fail radiation therapy at too high a rate. This article reviews the risk factors and methods of detection for prostate cancer recurrence. The relative merits of the three major pre-therapy prognostic indicators-TNM staging, Gleason score, and serum prostate-specific antigen (PSA) levels-are discussed. The use of staging and Gleason score, as well as digital rectal examination, transrectal ultrasound, and post-radiation prostate biopsies in ... Read More »
» Published in Rev Urol. 2002;4 Suppl 2:S2-S11.

20. Social anxiety and the shame of psychosis: A study in first episode psychosis.
Match Strength: 2.312

Social anxiety disorder (SaD) or social phobia is a co-morbid affective disorder in schizophrenia, present in up to one in three individuals. We employ 'social rank' theory to predict that one pathway to social anxiety in schizophrenia is triggered by the anticipation of a catastrophic loss of social status that the stigma of schizophrenia can entail. A group of 79 people with a first episode of psychosis were assessed for social anxiety: hypotheses were tested comparing 23 socially anxious and 56 non-anxious patients on measures of cognitive appraisals of shame/stigma of psychosis and ... Read More »
» Published in Behav Res Ther. 2006 Sep 25;

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