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Frontpage Footnotes for the Anti-inflammatory Diet Program

The Frontpage Footnotes and references or publication research sources and citations for the Anti-inflammatory diet program

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  1. "A nucleotide insertion in the transcriptional regulatory region of FADS2 gives rise to human fatty acid delta-6-desaturase deficiency", Journal of Lipid Research, Vol. 44, 2311-2319, December, 2003.
  2. "Identification of a fatty acid {Delta}6-desaturase deficiency in human skin fibroblasts", Journal of Lipid Research, Vol. 42, 501-508, April, 2001.
  3. "Suspected faulty essential fatty acid metabolism in Sjogren-Larsson syndrome", Pediatric Research, Vol 16, 45-49, 1982.
  4. "Green tea with a high catechin content suppresses inflammatory cytokine expression in the galactosamine-injured rat liver", Biomedical Research (Tokyo, Japan) 2005 Oct;26(5):187-92.
  5. "More tea for septic patients? - Green tea may reduce endotoxin-induced release of high mobility group box 1 and other pro-inflammatory cytokines", Medical Hypotheses, 2006;66(3):660-3. Epub 2005 Nov 2.
  6. "Immune cell activation and subsequent epithelial dysfunction by Staphylococcus enterotoxin B is attenuated by the green tea polyphenol (-)-epigallocatechin gallate" (EGCG from Green Tea), Cellular Immunology, 2005 Sep;237(1):7-16. Epub 2005 Oct 6.
  7. "Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells" (ECG from Green Tea), Carcinogenesis, Volume 25, Number 12, Pp. 2425-2432.
  8. "Green Tea Polyphenol Epigallocatechin-3-gallate (EGCG) Differentially Inhibits Interleukin-1{beta}-Induced Expression of Matrix Metalloproteinase-1 and -13 in Human Chondrocytes" (EGCG from Green Tea), Journal of Pharmacology And Experimental Therapeutics Fast Forward, November 4, 2003; DOI: 10.1124/jpet.103.059220.
  9. "Comparative effects of polyphenols from green tea (EGCG) and soybean (genistein) on VEGF and IL-8 release from normal human keratinocytes stimulated with the proinflammatory cytokine TNFalpha" (EGCG from Green Tea), Archives of Dermatological Research, 2003 Jul;295(3):112-6. Epub 2003 Jun 13.
  10. "Magnesium Intake, C-Reactive Protein, and the Prevalence of Metabolic Syndrome in Middle-Aged and Older U.S. Women", Diabetes Care 28:1438-1444, 2005, a publication of The American Diabetes Association.
  11. "Role of magnesium in insulin action, diabetes and cardio-metabolic syndrome X", Molecular Aspects of Medicine, 24:39-52, 2003.
  12. "Magnesium Replacement Therapy", The American Family Physician, 1990;42:173-6..
  13. "Bromelain (pineapple extract) as a Treatment for Osteoarthritis: a Review of Clinical Studies", Evidence Based Complementary and Alternative Medicine, 2004 December; 1(3): 251-257.
  14. "Punica granatum L. (pomegranate fruit) extract inhibits IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappaB in human chondrocytes in vitro", The Journal of Nutrition, 2005 Sep;135(9):2096-102.
  15. "S-Adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: A double-blind cross-over trial", BMC Musculoskeletal Disorders, February 26, 2004; 5: 6.
  16. "Tannic Acid Is an Inhibitor of CXCL12 (SDF-1{alpha})/CXCR4 with Antiangiogenic Activity", Clinical Cancer Research Vol. 9, 3115-3123, August 2003.
  17. "Possible immunomodulatory actions of Carica papaya seed extract", Clinical Hemorheology and Microcirculation 2003;29(3-4):219-29.
  18. "Silymarin (milk thistle extract) and skin cancer prevention: anti-inflammatory, antioxidant and immunomodulatory effects (Review)", International Journal of Oncology, 2005 Jan;26(1):169-76.
  19. "Combination anti-inflammatory therapy: synergism in rats of NSAIDs/corticosteroids with some herbal/animal products" (Indian Celery Seed & New Zealand Green-Lipped Mussel), Inflammopharmacology. 2003;11(4):453-64.
  20. "Systematic review of a marine nutriceutical supplement in clinical trials for arthritis: the effectiveness of the New Zealand green-lipped mussel Perna canaliculus", Clinical Rheumatology, 2005 Oct 12;:1-10.
  21. "Caffeic Acid Phenethyl Ester and Curcumin: A Novel Class of Heme Oxygenase-1 Inducers", Molecular Pharmacology, Vol. 61, Issue 3, 554-561, March 2002.
  22. "Anticachectic effects of Coptidis rhizoma, an anti-inflammatory herb, on esophageal cancer cells that produce interleukin 6" (Goldenseal), Cancer Letters, 2000 Sep 29;158(1):35-41.
  23. "Modulators of prostaglandin E2 synthesis in human amnion" (Aspirin, Acetaminophen), Journal of the Society Gynecologic Investigation, 1994 Apr-Jun;1(2):131-4.
  24. "Antagonists and inhibitors of lipid mediators in experimental inflammation of the cornea" (Fish Oil EPA/DHA), Journal of Ocular Pharmacology, 1993 Winter;9(4):365-72.
  25. "The effect of dietary fish oil supplement upon the content of dihomo-gammalinolenic acid in human plasma phospholipids" (Large doses of EPA reduce DGLA, suggesting use of Borage Oil with Fish Oil), Prostaglandins, Leukotrienes and Essential Fatty Acids. 1990 May;40(1):9-12.
  26. "Importance of Dietary Gamma-Linolenic Acid in Human Health and Nutrition" (Sources of GLA: Borage Oil, Black Currant Oil, Evening Primrose Oil), The Journal of Nutrition, Vol. 128 No. 9 September 1998, pp. 1411-1414.
  27. "Evening primrose oil and borage oil in rheumatologic conditions" (Sources of GLA), American Journal of Clinical Nutrition, Vol. 71, No. 1, 352S-356s, January 2000.
  28. "Borage oil reduction of rheumatoid arthritis activity may be mediated by increased cAMP that suppresses tumor necrosis factor-alpha" (Sources of GLA), International Immunopharmacology, 2001 Nov;1(12):2197-9.
  29. "Oral administration of gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, modulates interleukin-1beta production by human monocytes" (Borage Oil GLA), Journal of Clinical Immunology, 2002 Mar;22(2):83-91.
  30. "Diabetic neuropathy: pathogenesis and therapy" (Borage Oil, Source of GLA), The American Journal of Medicine, 1999 Aug 30;107(2B):17S-26S.
  31. "Dietary Supplementation with gamma -Linolenic Acid Alters Fatty Acid Content and Eicosanoid Production in Healthy Humans" (Borage Oil, Source of GLA), The Journal of Nutrition, Vol. 127 No. 8 August 1997, pp. 1435-1444.
  32. "Treatment of diabetic neuropathy with gamma-linolenic acid. The gamma-Linolenic Acid Multi-center Trial Group" (Borage Oil, Source of GLA), Diabetes Care. 1993 Jan;16(1):8-15.
  33. "The effect of gamma-linolenic acid on human diabetic peripheral neuropathy: a double-blind placebo-controlled trial" (Borage Oil, Source of GLA), Diabetic Medicine: A Journal of the British Diabetic Association, 1990 May;7(4):319-23.
  34. "Differential effects of prostaglandin derived from w-6 and w-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion" (Fish Oil, Source of EPA/DHA), Proceedings of the National Academy of Sciences of the United States of America, 2003 February 18; 100(4): 1751-1756.
  35. "Cellular interactions between n-6 and n-3 fatty acids: a mass analysis of fatty acid elongation/desaturation, distribution among complex lipids, and conversion to eicosanoids" (Role of Enzymes and Other Factors in Lipid Metabolism of Omega-3 vs. Omega-6 Fatty Acids), Journal of Lipid Research, 1992 Oct;33(10):1431-40.
  36. "Trans, trans-2,4-decadienal, a product found in cooking oil fumes, induces cell proliferation and cytokine production due to reactive oxygen species in human bronchial epithelial cells" (Protective role of N-Acetylcysteine NAC), Toxicological Sciences, 2005 Oct;87(2):337-43. Epub 2005 Jul 13.
  37. "Five Cysteine-Containing Compounds Delay Diabetic Deterioration in Balb/cA Mice" (Protective role of N-Acetyl-Cysteine NAC), The American Society for Nutritional Sciences J. Nutr. 134:3245-3249, December 2004.
  38. "N-acetylcysteine and alpha-tocopherol reverse the inflammatory response in activated rat Kupffer cells" (Protective role of N-Acetyl-Cysteine NAC), The Journal of Immunology, 1997 Jun 1;158(11):5418-23.
  39. "Cytokine secretion in whole blood of healthy subjects following oral administration of Urtica dioica L. plant extract" (Reduction of TNF-alpha and IL-6 by Nettle Leaf Extract, in German with English Abstract), Arzneimittelforschung. 1996 Sep;46(9):906-10.
  40. "Ameliorative effect of IDS 30, a stinging nettle leaf extract, on chronic colitis" (Reduction of Tumor Necrosis Factor-alpha by Nettle Leaf Extract and the extension of long-term remission from inflammatory bowel disease), International Journal of Colorectal Disease, 2005 Jan;20(1):9-17. Epub 2004 Aug 25.
  41. "Effects of sesamin and capsaicin on the mRNA expressions of delta6 and delta5 desaturases in rat primary cultured hepatocytes" (Sesame Seed Lignans - Sesamin - reduced activity of delta5 desaturase enzyme), Journal of Nutritional Science Vitaminology (Tokyo). 2003 Dec;49(6):442-6.
  42. "Interleukin 6 production by lipopolysaccharide-stimulated human fibroblasts is potently inhibited by naphthoquinone (vitamin K) compounds", Cytokine. 1995 Apr;7(3):287-90.

* All information on is for educational purposes only. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Before changing your diet, or adding supplements to your diet, or beginning an exercise program, everyone should consult a qualified and licensed health practitioner; a physician, dietician or similar professional.

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Replace omega-6 vegetable oils with omega-9 olive oil... Eat oily fish like tuna, sardines, anchovy, salmon, herring... Beans, lentils, peas add fiber... Nine or more 3-ounce servings of fruits or vegetables per day...