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Peer Reviewed Scientific Research Reports.
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1. Explaining paralysis in Chile's health sector, 1990-2000.
Match Strength: 8.107
This article looks at the health sector in Chile between 1990 and 2000 to examine the obstacles that policymakers face in implementing reforms. Given that the health sector is highly politicized, it is important to pay attention not only to what kind of reforms are needed but even more to how the desired reforms may be implemented. The author identifies the key actors in the Chilean health sector and shows how the given politico-institutional context allowed them to obstruct reforms. As a result, the health sector came to be characterized by paralysis, despite widespread recognition that ... Read More »
» Published in Int J Health Serv. 2006;36(3):605-22.
2. Antimicrobial susceptibility of strains of Propionibacterium acnes isolated from inflammatory acne.
Match Strength: 4.661
In the last decade, a significant increase in the antimicrobial resistance of clinical specimens of Propionibacterium acnes to first line antibiotics used for acne treatment, has been informed in Europe and in the USA. No information about strains isolated from Latin-American countries is available. The antimicrobial susceptibility of 53 strains of P. acnes isolated from skin specimens of inflammatory acne patients, at the clinical Hospital University of Chile was tested. All isolates were susceptible to penicillin, minocycline, and nadifloxacin. Erythromycin and clindamycin resistance was ... Read More »
» Published in Rev Latinoam Microbiol. 2006 Jan-Mar;48(1):14-6.
3. Comparison of tuberculin skin test response after three modalities of neonatal BCG vaccination.
Match Strength: 4.061
The aim of this study was to determine the tuberculin skin test (TST) response to three different BCG modalities [0.1ml Tokyo (n=104), 0.05ml Pasteur-Merieux (n=137) and 0.1ml Pasteur-Merieux (n=100)] in a cohort of healthy newborns 5 months after vaccination at birth in Santiago, Chile. Among the 341 infants, 91.2% had a response to TST, and the mean+/-SD TST reaction size was significantly larger in infants receiving the Tokyo strain than in those receiving the 0.05ml or 0.1ml Pasteur-Merieux strains (4.4+/-2.0, 3.5+/-1.3 and 3.1+/-1.4mm, respectively; P<0.0001). The mean+/-SD of the BCG ... Read More »
» Published in Trans R Soc Trop Med Hyg. 2006 Sep 22;
4. Cost-effectiveness of a fixed combination of hydroquinone/tretinoin/fluocinolone cream compared with hydroquinone alone in the treatment of melasma.
Match Strength: 3.927
BACKGROUND: A once-daily fixed combination of hydroquinone, tretinoin, and fluocinolone acetonide (Tri-luma) is a newly available treatment for melasma. OBJECTIVE: To assess cost-effectiveness of triple combination therapy (TCT) applied once daily and hydroquinone alone applied twice daily in the U.S., Argentina, Brazil, Chile, and Colombia from a payer's perspective. METHODS: Clinical data and utilization of key health resources (medication only) were assessed within an 8-week clinical trial conducted in Brazil. Total cost per primary success (complete clearing) was used to compare each ... Read More »
» Published in J Drugs Dermatol. 2007 Feb;6(2):153-60.
5. Medicinal wild plant knowledge and gathering patterns in a Mapuche community from North-western Patagonia.
Match Strength: 3.517
Medicinal plant use has persisted as a long standing tradition in the Mapuche communities of Southern Argentina and Chile. An ethnobotanical survey was conducted in the rural Curruhuinca community located near the mountain city of San Martin de los Andes, Argentina. Semi-structured interviews were carried out on 22 families in order to examine the present use of medicinal plants and their reputed therapeutic effects. Ecological variables, such as distance to the gathering site and biogeographical origin were also analyzed. Our results showed that the Curruhuinca dwellers cited 89 plant species ... Read More »
» Published in J Ethnopharmacol. 2006 Jan 3;103(1):109-19. Epub 2005 Sep 12.
6. Preventing copper intrauterine device removals due to side effects among first-time users: randomized trial to study the effect of prophylactic ibuprofen.
Match Strength: 3.510
BACKGROUND: Increased menstrual bleeding and pain are the primary side effects that lead to early removal of the copper intrauterine device (IUD). Ibuprofen and other non-steroidal anti-inflammatory drugs (NSAIDs) are proven treatments for such IUD-induced problems, but their effect on early IUD removal is unknown. METHODS: A total of 2019 first-time IUD users were recruited in Chile for this double-blind, randomized, placebo-controlled trial. Half of the participants were given ibuprofen and instructions to take 1200 mg daily during menses (for up to 5 days each cycle) for the first 6 months ... Read More »
» Published in Hum Reprod. 2006 Jun;21(6):1467-72. Epub 2006 Feb 16.
7. Disintegrated care: the Achilles heel of international health policies in low and middle-income countries.
Match Strength: 3.486
PURPOSE: To review the evidence basis of international aid and health policy. CONTEXT OF CASE: Current international aid policy is largely neoliberal in its promotion of commoditization and privatisation. We review this policy's responsibility for the lack of effectiveness in disease control and poor access to care in low and middle-income countries. DATA SOURCES: National policies, international programmes and pilot experiments are examined in both scientific and grey literature. CONCLUSIONS AND DISCUSSION: We document how health care privatisation has led to the pool of patients being cut ... Read More »
» Published in Int J Integr Care. 2006 Sep 18;6:e14.
8. Analgesic, anti-inflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae.
Match Strength: 3.002
ETHNOPHARMACOLOGICAL RELEVANCE: Buddleja globosa, known as "matico", is employed in Chile for wound healing. AIM OF THE STUDY: To validate the traditional use of the crude drug through in vivo and in vitro evaluation of the anti-inflammatory, analgesic and antioxidant properties of its extracts. MATERIALS AND METHODS: Sequential hexane, dichloromethane, methanol and total methanol extracts were studied using bioguided fractionation. The following activities were investigated: analgesic (writhing test), oral and topic anti-inflammatory (paw- and ear-induced edema), free radical scavenging and ... Read More »
» Published in J Ethnopharmacol. 2008 Mar 5;116(2):263-9. Epub 2007 Nov 22.
9. Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin.
Match Strength: 1.022
Capsicum-derived ingredients function as skin-conditioning agents--miscellaneous, external analgesics, flavoring agents, or fragrance components in cosmetics. These ingredients are used in 19 cosmetic products at concentrations as high as 5%. Cosmetic-grade material may be extracted using hexane, ethanol, or vegetable oil and contain the full range of phytocompounds that are found in the Capsicum annuum or Capsicum frutescens plant (aka red chiles), including Capsaicin. Aflatoxin and N-nitroso compounds (N-nitrosodimethylamine and N-nitrosopyrrolidine) have been detected as contaminants. The ... Read More »
» Published in Int J Toxicol. 2007;26 Suppl 1:3-106.
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