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Peer Reviewed Scientific Research Reports.
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1. Evidence for the benefits of prophylaxis in the management of hemophilia A.
Match Strength: 5.211
The optimal treatment of hemophilia has been evolving since the advent of factor VIII concentrates, continues to vary geographically, and remains a source of debate. There now exists an extensive clinical literature that demonstrates clear benefits of prophylaxis for patients with hemophiliaA compared to on-demand treatment, including a reduction in the number of bleeding episodes, improved joint function, and greater patient well-being. However, the value of these benefits must be weighed against the heavier economic burden of increased factor use. This paper reviews the literature that ... Read More »
» Published in Thromb Haemost. 2006 Oct;96(4):433-40.
2. Having sex and condom use: potential risks and benefits reported by young, sexually inexperienced adolescents.
Match Strength: 4.825
PURPOSE: This study determines what young adolescents themselves identify as the potential positive and negative outcomes of having sex, using a condom and not using a condom. METHODS: Using written surveys, 418 ethnically diverse ninth graders, 86% of whom had never had sex, responded to a scenario describing two adolescents who had sex. One randomly selected group read a scenario in which a condom was used; the other group read a scenario in which no condom was used. All participants were asked to list the risks and benefits of having sex. Depending on the scenario read, participants were ... Read More »
» Published in J Adolesc Health. 2006 Oct;39(4):588-95. Epub 2006 Jul 10.
3. The value of consulting in revenue cycle transformations: an analysis.
Match Strength: 4.388
The most often cited benefits of revenue cycle consulting engagements are improved cash receipts and reduced A/R days, both cited by 61 percent of study respondents. Most providers expressed confidence in their ability to sustain the initial realized benefits. A key disadvantage cited was that such highly visible and politically charged engagements require focused management time and attention that may be difficult to sustain ... Read More »
» Published in Healthc Financ Manage. 2006 Sep;60(9):60-7.
4. A novel dentifrice technology for advanced oral health protection: A review of technical and clinical data.
Match Strength: 4.297
Throughout the world, dentifrices have played a key role in the practice of good oral hygiene and promotion of better oral health. In addition to providing general dental cleaning, toothpastes also have served as an excellent vehicle for the introduction of new agents that deliver therapeutic and cosmetic benefits. Key examples of using dentifrices to provide added benefits include the introduction in 1955 of the first fluoridated toothpaste clinically proven to fight caries (Crest Cavity Protection) and the launch of the first tartar-control dentifrice (Crest Tartar Control) in the mid-1980s. ... Read More »
» Published in Compend Contin Educ Dent. 2005 Sep;26(9 Suppl 1):4-11.
5. Physical education and sport in schools: a review of benefits and outcomes.
Match Strength: 3.988
This paper explores the scientific evidence that has been gathered on the contributions and benefits of physical education and sport (PES) in schools for both children and for educational systems. Research evidence is presented in terms of children's development in a number of domains: physical, lifestyle, affective, social, and cognitive. The review suggests that PES have the potential to make significant and distinctive contributions to development in each of these domains. It is suggested that PES have the potential to make distinctive contributions to the development of children's ... Read More »
» Published in J Sch Health. 2006 Oct;76(8):397-401.
6. Combination therapy.
Match Strength: 3.835
So far, off-label recommendation of a combination therapy is mainly based on phase II study evidence and on largely accepted expert opinions. Combination therapy represents a new, more global strategy, to increase the possible benefits with the combined use of already available disease-modifying therapies or with other new agents, having an acceptable theoretical rationale and a good safety and efficacy profile. The therapeutic strategies of the near future will try to select among different and individualised combinations of drugs, with distinct mechanisms of action, and possibly with ... Read More »
» Published in Neurol Sci. 2006 Sep;27 Suppl 5:s350-4.
7. Stability of benefits of mime therapy in sequelae of facial nerve paresis during a 1-year period.
Match Strength: 3.782
OBJECTIVE: To assess the stability of benefits of mime therapy, a modality of physiotherapy for patients with facial nerve paresis, during a period of 1 year. STUDY DESIGN: A prospective follow-up build on a randomized clinical trial in which a treatment group is compared with a control group. SETTING: Physiotherapy outpatient department. PATIENTS: Forty-eight patients with a history of a facial nerve paresis of 9 months or more. INTERVENTION: Mime therapy. METHOD: Sequelae of facial nerve paresis were measured using the same measurement instruments as in the randomized clinical trial--the ... Read More »
» Published in Otol Neurotol. 2006 Oct;27(7):1037-42.
8. The genetic conception of health: is it as radical as claimed?
Match Strength: 3.695
The so-called new genetics is widely predicted to radically transform medicine and public health and deliver considerable benefits in the future. This article argues that, although it is doubtful that many of the promised benefits of genetic research will be delivered, an increasingly pervasive genetic worldview and expectations about future genetic innovations are profoundly shaping conceptions of health and illness and priorities in healthcare. Further, it suggests that debates about the normative and justice implications of new genetic technologies thus far have been constrained by ... Read More »
» Published in Health (London). 2006 Oct;10(4):481-500.
9. Role of lymphadenectomy for patients undergoing radical nephrectomy for renal cell carcinoma.
Match Strength: 3.506
The potential benefits of a lymph node dissection (LND) include more accurate staging, decreased local recurrence rates, and improved survival. However, only limited data support the potential benefits of routine, extensive LND for renal cell carcinoma (RCC). Because of lack of data, no clear practice standard has been established about whether to perform LND and, if so, to what extent. The value of LND for RCC is only relevant if the pattern of lymphatic spread is predictable, which it is not. However, although little evidence supports the value of LND for RCC, it is probable that an ... Read More »
» Published in Rev Urol. 2003 Summer;5(3):191-5.
10. Controversies in building a management algorithm for vestibular schwannomas.
Match Strength: 3.262
PURPOSE OF REVIEW: The present review examines the various mainstream treatment options, benefits and risks, and controversies involved in developing a management algorithm for treatment of vestibular schwannoma. RECENT FINDINGS: Advances in microsurgery and radiosurgery have made tremendous contributions to management of vestibular schwannoma; however, considerable controversy still exists. The auditory and facial nerve functional outcomes have improved with use of intraoperative monitoring for vestibular schwannoma removal and with lower radiosurgery doses; however, risks to the facial and ... Read More »
» Published in Curr Opin Otolaryngol Head Neck Surg. 2006 Oct;14(5):305-13.
11. Extrinsic whitening effects of sodium hexametaphosphate--a review including a dentifrice with stabilized stannous fluoride.
Match Strength: 3.051
The number of tooth whitening products available to patients has grown dramatically during recent years. While peroxide is the primary agent found in products that bleach and remove intrinsic sources of discoloration, various ingredients are incorporated in formulations to remove and inhibit extrinsic sources of tooth discoloration, ie, tooth stain. Recently, an advanced antitartar ingredient with extrinsic-stain-inhibiting benefits was introduced: sodium hexametaphosphate. This long-chain condensed phosphate, also known as polypyrophosphate, chemically removes existing stains and provides ... Read More »
» Published in Compend Contin Educ Dent. 2005 Sep;26(9 Suppl 1):47-53.
12. Understanding prebiotics in infant and childhood nutrition.
Match Strength: 3.002
Prebiotics and probiotics are ingredients in the diet that strengthen beneficial microbes in the gut, especially bifidobacteria. This article discusses their effects on health and their use in infant formula and foods for children and adults. They may also have benefits for the elderly population, since bifidobacteria are known to decrease with old age ... Read More »
» Published in J Fam Health Care. 2006;16(4):119-22.
13. Evidence-Based Health Benefits Management: Strategies to Optimize Antiretroviral Medication Adherence and Outcomes in HIV/AIDS.
Match Strength: 2.995
OBJECTIVE: To review how evidence-based principles can be applied to benefit design, specialty network management, and medication therapy management to successfully manage pharmaceutical benefits for patients infected with human immunodeficiency virus (HIV). SUMMARY: The most critical barrier to successfully managing HIV disease is suboptimal patient adherence to antiretroviral therapy. Managing HIV infection is unique in that the risk of treatment failure increases remarkably with even relatively minor lapses in patient adherence. The incremental cost of HIV treatment failure has been ... Read More »
» Published in J Manag Care Pharm. 2006 Sep;12(7 Suppl B):12-6.
14. Insurance coverage for obesity treatment.
Match Strength: 2.836
Recent work demonstrates the benefits of weight loss from intensive lifestyle modification. One barrier to counseling may be lack of reimbursement. We sought to quantify the obesity coverage policies of insurers in Pennsylvania. A three-page questionnaire was sent to eligible Pennsylvania health plans. Respondents included company medical directors and administrators from other departments, including public relations, provider relations, disease management, and utilization review. The questionnaire inquired about major treatment modalities for obesity, including details of coverage. Sixteen of ... Read More »
» Published in J Am Diet Assoc. 2006 Oct;106(10):1651-5.
15. The Use of Nomograms for Selecting BPH Candidates for Dutasteride Therapy.
Match Strength: 2.802
Recent studies have discussed the benefits of medical therapy for benign prostatic hyperplasia (BPH), but have not provided physicians with the necessary tools needed to translate the information into individualized, evidence-based recommendations for clinically important questions. Nomograms can help physicians individualize their treatment decisions and predict a likely outcome by assessing the key risk factors for BPH progression ... Read More »
» Published in Rev Urol. 2004;6 Suppl 9:S40-5.
16. Sustained antibacterial actions of a new stabilized stannous fluoride dentifrice containing sodium hexametaphosphate.
Match Strength: 2.653
Stannous fluoride has been used as a chemotherapeutic agent for years to improve oral health. The benefits of stannous fluoride in controlling caries, plaque, and gingivitis are directly associated with its antimicrobial actions. Recently, a novel dentifrice was developed that combines stannous fluoride with an anticalculus agent, sodium hexa. metaphosphate. A series of independent evaluations were conducted to assess the long-lasting antimicrobial activity of stannous fluoride in the new stannous fluoride/sodium hexametaphosphate dentifrice: an in vitro Live/Dead assay; an in vivo Plaque ... Read More »
» Published in Compend Contin Educ Dent. 2005 Sep;26(9 Suppl 1):19-28.
17. Risk acceptance in laryngeal transplantation.
Match Strength: 2.650
PURPOSE: Advancements in the fields of head and neck surgery and immunology have paved the way for new quality of life-improving procedures such as larynx transplantation. To quantitatively assess the risks versus benefits in larynx transplantation, we used a questionnaire-based survey (Louisville Instrument For Transplantation [LIFT]) to measure the degree of risk individuals are willing to accept to receive different types of transplantation procedures. METHODS: The LIFT contains 237 standardized questions incorporating standard gamble and time tradeoff outcome measures as well as questions ... Read More »
» Published in Laryngoscope. 2006 Oct;116(10):1770-5.
18. Design and implementation of an electronic data recording and processing system for physics quality control checks in external beam radiotherapy.
Match Strength: 2.648
Quality control (QC) of external beam radiotherapy equipment ensures that commissioning performance is maintained. Paper based data recording is still used for QC but this is resource intensive in terms of data calculation and processing. Electronic systems of data recording have many advantages; for example, they facilitate the analysis of data on a regular basis, allowing the user to examine the "health" of each machine; they help review and audit local frequencies of each check and can possibly predict component failure. They also allow for secure calculation of results and automatic ... Read More »
» Published in Br J Radiol. 2006 Sep 27;
19. Will choice-based reform work for Medicare? Evidence from the Federal Employees Health Benefits Program.
Match Strength: 2.636
OBJECTIVE:. To examine the effect of premiums and benefits on the health plan choices of older enrollees who choose Federal Employees Health Benefits Program (FEHBP) health plans as their primary payer. DATA SOURCES: Administrative enrollment data from the Office of Personnel Management (OPM) and plan premiums and benefits data taken from the Checkbook Guide to health plans. STUDY DESIGN: We estimate individual plan choice models where the choice of health plan is a function of out-of-pocket premium, actuarial value, plan attributes, and individual characteristics. Plan attributes include plan ... Read More »
» Published in Health Serv Res. 2006 Oct;41(5):1741-61.
20. An evaluation of an abstinence-only sex education curriculum: an 18-month follow-up.
Match Strength: 2.598
The article examines the results from an 18-month follow-up evaluation of an abstinence education curriculum series. Participants were students from 15 school districts recruited to participate in the project. The intervention was the Sex Can Wait curriculum series, consisting of upper elementary, middle school, and high school components. The 5-week curriculum was implemented by teachers who had participated in a special teacher training workshop. Both intervention and comparison students were surveyed before and after the curriculum intervention and at 18-month follow-up. Results indicated ... Read More »
» Published in J Sch Health. 2006 Oct;76(8):414-22.
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