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Peer Reviewed Scientific Research Reports.
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1. Dietary spices in health and diseases: I.
Match Strength: 12.360
Spices are heterogeneous collections of a wide variety of volatile and non-volatile staple dietary additives. India with its wide climatic conditions and topographical features naturally possesses wide variety of medicinal flora. Spices have a diverse array of natural phytochemicals that have complementary and overlapping actions, including antioxidant effects, modulation of detoxification enzymes, stimulation of immune system, reduction of inflammation, modulation of steroid metabolism and antibacterial and antiviral effects. In the present essay, various studies on effects of different well ... Read More »
» Published in Indian J Physiol Pharmacol. 2008 Apr-Jun;52(2):106-22.
2. Health benefits of herbs and spices: the past, the present, the future.
Match Strength: 7.497
Herbs and spices have a traditional history of use, with strong roles in cultural heritage, and in the appreciation of food and its links to health. Demonstrating the benefits of foods by scientific means remains a challenge, particularly when compared with standards applied for assessing pharmaceutical agents. Pharmaceuticals are small-molecular-weight compounds consumed in a purified and concentrated form. Food is eaten in combinations, in relatively large, unmeasured quantities under highly socialised conditions. The real challenge lies not in proving whether foods, such as herbs and spices ... Read More »
» Published in Med J Aust. 2006 Aug 21;185(4 Suppl):S4-24.
3. Molecular targets of -gingerol: Its potential roles in cancer chemoprevention.
Match Strength: 6.333
A wide variety of phenolic compounds derived from spices possess potent antioxidant, anti-inflammatory, antimutagenic, and anticarcinogenic activities. -gingerol (1-[4'-hydroxy-3'-methoxyphenyl]-5-hydroxy-3-decanone) is the major pungent principle of ginger, with numerous pharmacological properties including antioxidant, anti-inflammation, and antitumor promoting properties. It could decrease inducible nitric oxide synthase (iNOS) and tumor necrosis factor alpha (TNF-alpha) expression through suppression of I-kappaB alpha (IkappaBalpha) phosphorylation, nuclear factor kappa B (NF-kappaB) ... Read More »
» Published in Biofactors. 2010 May-Jun;36(3):169-78.
4. Phenylpropanoids as naturally occurring antioxidants: from plant defense to human health.
Match Strength: 5.538
Phenylpropanoids (PPs) belong to the largest group of secondary metabolites produced by plants, mainly, in response to biotic or abiotic stresses such as infections, wounding, UV irradiation, exposure to ozone, pollutants, and other hostile environmental conditions. It is thought that the molecular basis for the protective action of phenylpropanoids in plants is their antioxidant and free radical scavenging properties. These numerous phenolic compounds are major biologically active components of human diet, spices, aromas, wines, beer, essential oils, propolis, and traditional medicine. Last ... Read More »
» Published in Cell Mol Biol (Noisy-le-grand). 2007 Apr 15;53(1):15-25.
5. Determination of active components in rosemary by capillary electrophoresis with electrochemical detection.
Match Strength: 5.473
Rosemary (Rosmarinus officinalis L.) is a spice and medicinal herb widely used around the world. Among natural antioxidants, rosemary has been widely accepted as one of the spices with the highest antioxidant activity. A capillary electrophoresis method for the determination of its active components using electrochemical detection was developed. Effects of several important factors were investigated to acquire the optimum conditions. The detection electrode was a 300 microm carbon disc electrode at a working potential of +0.90 V (versus SCE). The analytes can be well separated with 25 min in a ... Read More »
» Published in J Pharm Biomed Anal. 2005 Sep 15;39(3-4):431-7.
6. The role of chalcones in suppression of NF-?B-mediated inflammation and cancer.
Match Strength: 5.096
Although consumption of fruits, vegetables, spices, cereals and pulses has been associated with lower incidence of cancer and other chronic diseases, how these dietary agents and their active ingredients minimize these diseases, is not fully understood. Whether it is oranges, kawa, hops, water-lilly, locorice, wax apple or mulberry, they are all connected by a group of aromatic ketones, called chalcones (1,3-diaryl-2-propen-1-ones). Some of the most significant chalcones identified from these plants include flavokawin, butein, xanthoangelol, 4-hydroxyderricin, cardamonin, 2',4' ... Read More »
» Published in Int Immunopharmacol. 2011 Mar;11(3):295-309. Epub 2010 Dec 22.
7. Anti-inflammatory plant natural products for cancer therapy.
Match Strength: 5.050
Much of the current research in cancer therapeutics is aimed at developing drugs or vaccines to target key molecules for combating tumor cell growth, metastasis, proliferation, or changes in the associated stromal microenvironment. Studies on a wide spectrum of plant secondary metabolites extractable as natural products from fruits, vegetables, teas, spices, and traditional medicinal herbs show that these plant natural products can act as potent anti-inflammatory, antioxidant or anticancer agents. The recent advances in genomics and metabolomics have enabled biologists to better investigate ... Read More »
» Published in Planta Med. 2010 Aug;76(11):1103-17. Epub 2010 Apr 29.
8. Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals.
Match Strength: 4.402
Extensive research within the past two decades has revealed that obesity, a major risk factor for type 2 diabetes, atherosclerosis, cancer, and other chronic diseases, is a proinflammatory disease. Several spices have been shown to exhibit activity against obesity through antioxidant and anti-inflammatory mechanisms. Among them, curcumin, a yellow pigment derived from the spice turmeric (an essential component of curry powder), has been investigated most extensively as a treatment for obesity and obesity-related metabolic diseases. Curcumin directly interacts with adipocytes, pancreatic cells, ... Read More »
» Published in Annu Rev Nutr. 2010 Aug 21;30:173-99.
9. Curcumin content of turmeric and curry powders.
Match Strength: 4.351
Curcumin, derived from the rhizome curcuma longa, is one of the primary ingredients in turmeric and curry powders that are used as spices in Middle Eastern and Asian countries, especially on the Indian subcontinent. More recently, laboratory studies have demonstrated that dietary curcumin exhibits various biological activities and significantly inhibits colon tumorigenesis and tumor size in animals. Curcumin displays both anti-inflammatory and antioxidant properties, giving it the potential to be considered in the development of cancer preventive strategies and applications in clinical ... Read More »
» Published in Nutr Cancer. 2006;55(2):126-31.
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