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Helminthiasis
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1. Effect of intestinal helminthiasis on nutritional status of schoolchildren.
Match Strength: 11.234

This study was conducted in a rural agricultural area in Siniloan, Republic of the Philippines. The subjects were the school children. The nutritional status of 58 children infected with helminthiasis (Ascaris lumbricoides and Trichuris trichiura) was compared with that of 19 uninfected controls. Prevalence of Ascaris and Trichuris was 40.3% and 71.4% respectively, and 36.4% of infected children had both Ascaris and Trichuris infections. Statistically significant evidence of an adverse effect of helminthiasis on serum albumin levels was found, but no child had inadequate levels of other ... Read More »
» Published in Southeast Asian J Trop Med Public Health. 2000 Dec;31(4):755-61.

2. Do helminths play a role in carcinogenesis?
Match Strength: 10.989

Chronic helminthiasis is recognized as a significant factor in cancer development in humans. However, the mechanisms by which helminths initiate and promote malignant transformation of host cells are still not understood fully. Human helminthiasis can cause genetic instability and affect inter- and intracellular communication, ultimately leading to tumour development through inflammation, modulation of the host immune system, and secretion of soluble factors that interact with host cells ... Read More »
» Published in Trends Parasitol. 2001 Apr;17(4):172-5. Comment in: Trends Parasitol. 2001 Nov;17(11):516; author reply 517.

3. Intestinal Helminthiasis in Colombian Children Promotes a Th2 Response to Helicobacter Pylori: Possible Implications for Gastric Carcinogenesis
Match Strength: 10.309

BACKGROUND: Colombians living in coastal Tumaco have a lower incidence of Helicobacter pylori-associated gastric cancer compared with residents of Pasto in the high Andes. Considering the risk for H. pylori disease seems affected by features of bacterial virulence and host polymorphisms, other poorly understood influences, such as concurrent helminthiasis, may also be important. METHODS: Fecal samples from 211 children were tested for parasites and sera from another cohort of 159 children and 92 adults were tested for IgE and H. pylori-specific IgG. RESULTS: Most individuals (95%) from both ... Read More »
» Published in Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1464-9.

4. Mass treatment for intestinal helminthiasis control in an Amazonian endemic area in Brazil.
Match Strength: 8.982

The objective of the present study was to estimate the prevalence of soil-transmitted helminthiasis and evaluate the sanitary conditions and the role of a mass treatment campaign for control of these infections in Santa Isabel do Rio Negro. A cross-sectional survey was carried out in 2002, to obtain data related to the sanitary conditions of the population and fecal samples for parasitological examination in 308 individuals, followed by a mass treatment with albendazole or mebendazole with coverage of 83% of the city population in 2003. A new survey was carried out in 2004, involving 214 ... Read More »
» Published in Rev Inst Med Trop Sao Paulo. 2006 Jul-Aug;48(4):189-95.

5. A six-year follow-up of schoolchildren for urinary and intestinal schistosomiasis and soil-transmitted helminthiasis in Northern Tanzania.
Match Strength: 8.793

Two cross-sectional studies with a 6-year interval were undertaken in two primary schools in neighbouring villages in Mwanga District, Tanzania, to determine the prevalence of schistosome and soil-transmitted helminth infections before and 6 years after treatment. Within this interval, health-related interventions such as one mass treatment of the villagers, health education, improvement of sanitation and access to safe water were undertaken in the villages. In 1996, urinary schistosomiasis occurred in Kileo (n=284) and Kivulini (n=350) in 37.0 and 86.3% of the schoolchildren. Intestinal ... Read More »
» Published in Acta Trop. 2005 Feb;93(2):131-40. Epub 2004 Dec 15.

6. Intervention for the control of soil-transmitted helminthiasis in the community.
Match Strength: 7.697

The global strategy for the control of soil-transmitted helminthiasis, based on regular anthelminthic treatment, health education and improved sanitation standards, is reviewed. The reasons for the development of a control strategy based on population intervention rather than on individual treatment are explained. The evidence and experience from control programmes that created the basis for (i) the definition of the intervention package, (ii) the identification of the groups at risk, (iii) the standardization of the community diagnosis and (iv) the selection of the appropriate intervention ... Read More »
» Published in Adv Parasitol. 2006;61:311-48.

7. Effect of intestinal helminthiasis on intestinal permeability of early primary schoolchildren.
Match Strength: 7.628

Intestinal permeability of 246 early primary schoolchildren at 2 schools (106 of whom were infected with intestinal helminths) was assessed by using the lactulose/mannitol differential absorption test. The ratio of the urinary recoveries of lactulose and mannitol was determined after oral administration of a standard solution of the 2 sugars. Assessment of intestinal permeability was repeated on 100 infected children after treatment and on a cohort of 68 uninfected children. Infected and uninfected groups were compared with respect to baseline lactulose/mannitol ratio (L/M1) and change in ... Read More »
» Published in Trans R Soc Trop Med Hyg. 1996 Nov-Dec;90(6):666-9.

8. A combined school- and community-based campaign targeting all school-age children of Burkina Faso against schistosomiasis and soil-transmitted helminthiasis: performance, financial costs and implications for sustainability.
Match Strength: 7.443

A combined school- and community-based campaign targeting the entire school-age population of Burkina Faso with drugs against schistosomiasis (praziquantel) and soil-transmitted helminthiasis (albendazole) was implemented in 2004-2005. In total, 3,322,564 children from 5 to 15 years of age were treated, equivalent to a 90.8% coverage of the total school-age population of the country. The total costs of the campaign were estimated to be US 1,067,284 dollars, of which 69.4% was spent on the drugs. Delivery costs per child treated were US 0.098 dollar, in the same range as school-based only ... Read More »
» Published in Acta Trop. 2006 Oct;99(2-3):234-42. Epub 2006 Sep 25.

9. Paradoxical helminthiasis and giardiasis in Cape Town, South Africa: epidemiology and control.
Match Strength: 7.251

Background: South Africa has endorsed a World Health Assembly (WHA) resolution calling for control of soil-transmitted helminths (STHs). In Cape Town, services and housing that exist in old-established suburbs should minimise the prevalence of intestinal parasitic infections, even when residents are poor. Where families live in shacks in densely-populated areas without effective sanitation, more than 90% of children can be infected by STHs. The humoral immune response to worms theoretically favours infection by Mycobacterium tuberculosis and HIV. Objectives: Obtain estimates of gender-, age-, ... Read More »
» Published in Afr Health Sci. 2005 Sep;5(3):276-80.

10. Community's willingness to pay for a school-based chemotherapy programme to control morbidity due to schistosomiasis and soil-transmitted helminthiasis in children in rural Tanzania.
Match Strength: 7.197

A cross-sectional questionnaire survey was conducted on a random sample of 523 households having at least one child attending primary school in 3 villages in Buchosa Division, Sengerema District, Tanzania. The aim was to determine the community's willingness to pay (WTP) for a school-based chemotherapy programme to control morbidity due to schistosomiasis and soil-transmitted helminthiasis (STH) in schoolchildren and identify socio-economic and cultural factors influencing community's WTP. Results showed that households WTP for a school-based chemotherapy programme varied from Tanzanian ... Read More »
» Published in Tanzan Health Res Bull. 2005 Sep;7(3):149-53.

11. Helminthiasis and culture change among the Cofan of Ecuador.
Match Strength: 7.145

Blood and fecal samples and lifestyle interviews were obtained in August 1996 from two Cofan villages in Ecuador, Dureno and Zabalo, that are experiencing different degrees of acculturation. Dureno's territory has been divided by roads and encroached upon by oil companies and colonists, whereas Zabalo, 95 km downriver from Dureno, is located in the Cuyabeno Fauna Reserve, a protected area. This study examines how culture change affects the prevalence of parasitic infections. Fecal samples were examined for helminth eggs to determine helminthiasis in each village sample. Seventy-four samples ... Read More »
» Published in Am J Hum Biol. 2000 Jul;12(4):465-477.

12. Paradoxical helminthiasis and giardiasis in Cape Town, South Africa: epidemiology and control.
Match Strength: 7.120

BACKGROUND: South Africa has endorsed a World Health Assembly (WHA) resolution calling for control of soil-transmitted helminths (STHs). In Cape Town, services and housing that exist in old-established suburbs should minimise the prevalence of intestinal parasitic infections, even when residents are poor. Where families live in shacks in densely-populated areas without effective sanitation, more than 90% of children can be infected by STHs. The humoral immune response to worms theoretically favours infection by Mycobacterium tuberculosis and HIV. OBJECTIVES: Obtain estimates of gender-, age-, ... Read More »
» Published in Afr Health Sci. 2005 Jun;5(2):131-6.

13. Triple co-administration of ivermectin, albendazole and praziquantel in zanzibar: a safety study.
Match Strength: 6.828

BACKGROUND: Public health interventions based on distribution of anthelminthic drugs against lymphatic filariasis (LF), onchocerciasis, soil-transmitted helminthiasis (STH) and schistosomiasis have been implemented separately to date. A better use of available resources might be facilitated by a more coordinated approach to control such infections, including the possibility of co-administering the three recommended anthelminthic drugs through a single, large-scale intervention. METHODOLOGY/PRINCIPAL FINDINGS: Ivermectin, albendazole and praziquantel were co-administered to 5,055 children and ... Read More »
» Published in PLoS Negl Trop Dis. 2008 Jan 23;2(1):e171.

14. Potential for integrated control of neglected tropical diseases in Ethiopia.
Match Strength: 5.806

Ethiopia is one of the poorest and least developed countries in the world, endemic for many neglected tropical diseases (NTDs). The Ministry of Health is successfully controlling onchocerciasis through community-directed treatment with ivermectin and has implemented health system changes that would allow extension of integrated NTD control to schistosomiasis, lymphatic filariasis, soil-transmitted helminthiasis and trachoma. Funds are now needed to gain a better understanding of the endemicity and co-endemicity of these diseases and to formulate and pilot integrated packages for mass drug ... Read More »
» Published in Trans R Soc Trop Med Hyg. 2008 Mar;102(3):213-4. Epub 2007 Oct 22.

15. Mortality of domesticated java deer attributed to Surra.
Match Strength: 5.797

This paper reports an outbreak of trypanosomiasis due to Trypanosoma evansi in Java deer (Cervus timorensis) on a government deer farm in Lenggong, Perak. Seventeen adult female Java deer were found dead within a week. Symptoms of dullness, inappetence, anaemia, anorexia, respiratory distress and recumbency were seen prior to death in the infected Java deer. Beside trypanosomiasis, other parasitic infections such as theileriosis, helminthiasis and ectoparasite infestation were also recorded. Post mortem results showed generalized anaemia in most animals with isolated cases of jaundice. There ... Read More »
» Published in Trop Biomed. 2007 Dec;24(2):67-70.

16. Human eosinophils as potent inflammatory cells and their apoptosis
Match Strength: 5.646

A significant association was established between the eosinophil and a number of disease conditions, including helminthiasis, allergy, asthma, drug hypersensitivity, certain neoplasias, and graft rejection. Activation of eosinophils and release of proinflammatory lipid mediators, cytokines, free oxygen radicals, highly-charged cationic proteins contribute to the onset and maintenance of tissue inflammation. Eosinophil accumulation in blood and tissues has been related to a defect in their apoptotic death. Decisive events during the apoptotic process involve mitochondrial permeabilization and ... Read More »
» Published in Bratisl Lek Listy. 2004;105(10-11):359-61.

17. Ascaris, co-infection and allergy: the importance of analysis based on immunological variables rather than egg excretion.
Match Strength: 5.640

The ratio of Ascaris seropositivity to the presence of eggs in the faeces was 2.44 in children residing near Cape Town, South Africa. Similar and larger ratios have previously been described for children and women living in the city. The new finding strengthens the concept that when helminthic infections occur together with non-helminthic diseases, an analysis of the interaction must include the use of disease-related immunological variables and not be based only on egg excretion status. One of the reasons is that many egg-negative people who live where helminthiasis is highly endemic are ... Read More »
» Published in Trans R Soc Trop Med Hyg. 2007 Jan 23;

18. Invasive enteritis by Strongyloides stercoralis presenting as acute abdominal distress under corticosteroid therapy.
Match Strength: 5.489

Overwhelming helminthiasis is still a problem in endemic areas, especially in immunocompromised patients. We report a case of invasive intestinal strongyloidiasis that was clinically expressed as acute abdominal distress in a 73-year-old man from Sao Paulo who had been receiving methylprednisone, 20 mg/day, for one year for osteoarthritis. A surgical specimen from the ileum revealed invasive enteritis with severe infestation by Strongyloides stercoralis. The patient died of sepsis 6 days after surgery. The possibility of invasive strongyloidiasis should be considered in the differential ... Read More »
» Published in Rev Hosp Clin Fac Med Sao Paulo. 2001 Jul-Aug;56(4):103-6.

19. A blueprint for success: integration of neglected tropical disease control programmes.
Match Strength: 5.354

The rapid expansion of chemotherapy-based control programmes for neglected tropical diseases has been catalysed by funding from the Bill and Melinda Gates Foundation, donations of several drugs from pharmaceutical manufacturers, and the reduced price of the drug praziquantel. Focussing on lymphatic filariasis, schistosomiasis and soil-transmitted helminthiasis, we review here the progress made to date with the implementation and integration of large-scale control programmes. Unresolved issues include a means for rapid identification of communities at highest risk of co-morbidity, cost ... Read More »
» Published in Trends Parasitol. 2006 Jul;22(7):313-21. Epub 2006 May 19.

20. Status of soil transmitted helminthiasis in UT of Lakshadweep.
Match Strength: 5.337

Soil Transmitted Helminthes (STH) survey in UT of Lakshadweep was conducted during February-March 2004. The survey was undertaken using WHO sampling methodology and Kato-Katz technique for stool sample examination. A total of 387 stool samples were examined of whom 322 samples (83.2%) were found positive for one or more STH. Maximum prevalence (100%) was found in Kavaratti Junior Basic School. Thirty children (7.8%) had high intensity of infection. In Kadmat Junior Basic School high intensity TT infection was 8.9%, For AL highest intensity of infection was found among Kavaratti Senior Basic ... Read More »
» Published in J Commun Dis. 2005 Jun;37(2):121-4.

21. Endoscopic removal of Ascaris lumbricoides from the biliary tract as emergency treatment for acute suppurative cholangitis.
Match Strength: 5.168

Ascariasis is the most common intestinal helminthiasis worldwide. Heavily infected individuals are prone to develop bowel obstruction or perforation as well as biliary disease. Nevertheless, the presence of roundworms in the biliary tree outside endemic areas is very uncommon. The migration of these worms to the biliary system can cause biliary colic, pancreatitis, or even acute suppurative cholangitis with hepatic abscesses and septicemia.We report here on 2 infants with 14 and 15 months and a 9-year-old boy who suffered from massive biliary ascariasis and who presented with acute suppurative ... Read More »
» Published in Z Gastroenterol. 2001 Sep;39(9):793-6.

22. Projected benefits from integrating NTD programs in sub-Saharan Africa.
Match Strength: 5.054

The integration of preventive chemotherapy programs (PCPs) targeting multiple neglected tropical diseases (NTDs) with similar strategic approaches offers opportunities for enhanced cost-effectiveness. To estimate the potential cost savings and health outcomes of integrated programs, the data available for five NTDs (lymphatic filariasis, onchocerciasis, intestinal helminthiasis, schistosomiasis and trachoma) can be used to define eligible target populations, the probable overlap of at-risk populations, and the cost per person treated in stand-alone and integrated programs. If all targets for ... Read More »
» Published in Trends Parasitol. 2006 Jul;22(7):285-91. Epub 2006 May 26.

23. Hepatosplenic schistosomiasis. Pathophysiology and treatment
Match Strength: 4.856

HSS represents a special model of intrahepatic portal hypertension characterized by a presinusoidal portal block and a well-preserved liver parenchyma. Symmers' fibrosis appears in a small but significant proportion of patients with a high worm load. Its pathogenesis is not well established, although experimental and clinical studies point to egg granulomata as the main pathogenetic factor. The eggs carried continuously through the portal circulation produce inflammation and gross amputation of the intrahepatic veins, portal and periportal granulomas, and, eventually, a coarse perilobular ... Read More »
» Published in Gastroenterol Clin North Am. 1992 Mar;21(1):163-77.

24. Efficacy and safety of drug combinations in the treatment of schistosomiasis, soil-transmitted helminthiasis, lymphatic filariasis and onchocerciasis.
Match Strength: 4.821

This review concerns the efficacy and safety of combinations of various drugs, including albendazole (ALB), diethylcarbamazine (DEC), ivermectin (IVM), mebendazole and praziquantel (PZQ). There were no significant pharmacokinetic interactions when ALB-PZQ, ALB-DEC, ALB-IVM or ALB-IVM-PZQ were co-administered. ALB did not add to the cure rate of PZQ in the treatment of Schistosoma japonicum, S. mansoni and S. haematobium. ALB and DEC in combination and alone were ineffective against S. haematobium infections. No combinations (ALB-PZQ, ALB-IVM and ALB-DEC) were superior to ALB against Ascaris ... Read More »
» Published in Trans R Soc Trop Med Hyg. 2007 Aug;101(8):747-58. Epub 2007 May 3.

25. Parasitic infestations of the biliary tract.
Match Strength: 4.743

Parasitic infestations of the biliary tract are a common cause of biliary obstruction in tropical countries and can lead to such serious complications as cholangitis and cholangiocarcinoma. Endoscopic therapy has helped in the management of biliary complications caused by these parasites. Ascaris lumbricoides organisms, which normally reside in the jejunum, are actively motile and can invade the papilla, thus migrating into the bile duct and causing biliary obstruction. Endoscopic retrograde cholangiopancreatography is a useful diagnostic tool with potential for therapeutic management of ... Read More »
» Published in Curr Gastroenterol Rep. 2007 Apr;9(2):156-64.

26. Hookworm infestation in a 3-month old female.
Match Strength: 4.639

BACKGROUND: Intestinal helminthiasis is a major cause of morbidity and mortality in infants and children particularly in the tropics and subtropics. This report highlights the possibility of hookworm infestation in infancy. METHOD: A case report of hookworm infestation in a three-month old infant who was managed in the University of Port Harcourt Teaching Hospital, Port Harcourt in May 2001 for failure to thrive and recurrent severe anaemia. RESULT: The patient was admitted in the children's emergency ward with passage of dark watery stools, fever, excessive crying and severe anemia and was ... Read More »
» Published in Niger J Med. 2005 Apr-Jun;14(2):227-30.

27. Gongylonematiasis in the common marmoset (Callithrix jacchus).
Match Strength: 4.559

Two cases of gongylonematiasis in common marmosets of two research facilities in Germany are reported. The helminthiasis was transmitted from colony A to colony B by one infected female and within colony B by cockroaches (Blatella germanica). Four of 40 cockroaches examined in colony B were infected with rhabditiform larvae. Clinical signs of disease in the infected animals consisted of intense itching and scratching of the edematous and slightly hyperemic perioral tissues. Histologically the adult helminths lodged predominantly in the mucous membranes of the upper and lower lips; they were ... Read More »
» Published in Lab Anim Sci. 1996 Jun;46(3):266-70.

28. Distribution of enterobiasis among nursery school children in SE Estonia and of other helminthiases in Estonia.
Match Strength: 4.488

The occurrence of helminthiases in Estonia was under extensive observation from 1956 until 1989. Enterobiasis had remained the most prevalent helminthiasis in Estonia in the 1990s. After 1990, the number of helminthological studies decreased. This study was conducted to investigate the occurrence and possible risk factors of enterobiasis among nursery school children in Southeast Estonia. A total of 954 nursery school children were examined from 22 nursery schools in Tartu and Polva counties in Estonia. Enterobius vermicularis infection was detected using the anal swab technique. The parents ... Read More »
» Published in Parasitol Res. 2006 Nov;99(6):729-36. Epub 2006 Jun 3.

29. Multiple infection diagnosis of intestinal helminthiasis in the assessment of health and environmental effect of development projects in Nigeria.
Match Strength: 4.455

Patterns of intestinal helminth infections among school-aged children have been assessed in Eko-ende and Ore, as part of an overall assessment of the public health impact of Erinle Dam Reservoir in Osun State, Nigeria. The investigation was carried out between January and May 2005 using the Kato Katz thick smear technique and simple questionnaire for information on the bio-data, knowledge, attitude and practice of individuals towards disease transmission and control. Ascaris lumbricoides, hookworm, Trichuris trichiura, Taenia spp., Strongyloides stercoralis and Schistosoma mansoni were ... Read More »
» Published in J Helminthol. 2007 Jun 21;:1-5

30. Effect of Rhazya stricta on the developing rat fetus.
Match Strength: 4.376

Rhazya stricta is a medicinal plant traditionally used in the treatment of diabetes mellitus, inflammation, and helminthiasis. Our objective was to determine if the plant extract has any effect on fetal development in the rat. A lyophilized extract of the plant was administered daily on three consecutive gestation days (GD) covering the period of preimplantation and organogenesis. The fetuses were examined on GD 20. Higher doses (5.0 or 8.0 g/kg) of R. stricta generally caused a reduction in maternal weight gain, compared to controls, whereas the lower doses (0.5 to 2.0 g/kg) did not. ... Read More »
» Published in Reprod Toxicol. 1997 Mar-Jun;11(2-3):191-9.

31. Mental and behavioral effects of parasitic infections: a review.
Match Strength: 4.334

Whether parasitic diseases-and in particular helminth infections because they are extensive and widespread--have an effect on mental functions and educational attainment is by no mean a new question. Concern about the possibility was evident in the early decades of the century, and the results of investigations designed to discover whether the effects of parasite infections had consequences on school children. Many species of helminth have been reported as causing infections in humans. Of the nematode infections, both soil transmitted helminthiasis and lymphatic filariasis are public health ... Read More »
» Published in Nepal Med Coll J. 2007 Mar;9(1):50-6.

32. The reflection of control programs of parasitic diseases upon gastrointestinal helminthiasis in Dakahlia Governorate, Egypt.
Match Strength: 4.260

The study area included Mansoura city as an urban area and Gogar village as a rural area. One thousand individuals were randomly selected from each area. Different methods of stool examination, perianal swab and urine examination of all participants revealed that the incidence in Mansoura city was in a descending order Heterophyes heterophyes 6.4%; Enterobius vermicularis 3.9%; Hymenienolepis nana 2.2%; Schistosoma mansoni 0.5%; Trichostrongylus colubriftormis; Strongyloides stercoralis and Fasciola sp. were recorded as 0.2% of each. Taenia saginata, Ascaris lumbricoides and Trichocephalus ... Read More »
» Published in J Egypt Soc Parasitol. 2006 Aug;36(2):467-80.

33. Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research.
Match Strength: 4.165

Ginger (Zingiber officinale Roscoe, Zingiberacae) is a medicinal plant that has been widely used in Chinese, Ayurvedic and Tibb-Unani herbal medicines all over the world, since antiquity, for a wide array of unrelated ailments that include arthritis, rheumatism, sprains, muscular aches, pains, sore throats, cramps, constipation, indigestion, vomiting, hypertension, dementia, fever, infectious diseases and helminthiasis. Currently, there is a renewed interest in ginger, and several scientific investigations aimed at isolation and identification of active constituents of ginger, scientific ... Read More »
» Published in Food Chem Toxicol. 2008 Feb;46(2):409-20. Epub 2007 Sep 18.

34. Sensitization to Ascaris lumbricoides and severity of childhood asthma in Costa Rica.
Match Strength: 4.159

BACKGROUND: Little is known about sensitization (defined as a positive IgE) to helminths and disease severity in patients with asthma. OBJECTIVES: To examine the relationship between sensitization (defined as a positive IgE) to Ascaris lumbricoides and measures of asthma morbidity and severity in a Costa Rican population with low prevalence of parasitic infection but high prevalence of parasitic exposure. METHODS: Cross-sectional study of 439 children (ages 6 to 14 years) with asthma. Linear regression and logistic regression were used for the multivariate statistical analysis. RESULTS: After ... Read More »
» Published in J Allergy Clin Immunol. 2007 Mar;119(3):654-61.

35. Intestinal parasitic infections and eosinophilia in an human immunedeficiency virus positive population in Honduras.
Match Strength: 4.155

The occurrence of intestinal parasites, their regional distribution and their relations to eosinophilia were studied in 133 human immunodeficiency virus (HIV) positive individuals from Honduras. After signing an informed consent, participants answered a socio-demographic and risk factor questionnaire, a complete physical examination, medical history, and a series of laboratory tests. All participants were HIV positive but not acquired immunodeficiency syndrome positive. Of them, 67% were co-infected with pathogen and non pathogen parasites. Overall occurrence of nematodes was: 44.3% for ... Read More »
» Published in Mem Inst Oswaldo Cruz. 2004 Nov;99(7):773-8. Epub 2005 Jan 12.

36. Intestinal helminthes and/or Toxocara infection are unrelated to anti-HBs titers in seven-year-old children vaccinated at birth with recombinant hepatitis B vaccine.
Match Strength: 4.104

The aim of this investigation was to evaluate the possible effect of nematode infection on anti-HBs antibody levels in the serum of seven-year-old schoolchildren vaccinated at birth with the recombinant hepatitis B vaccine. Anti-HBs and anti HBc antibodies were evaluated in the sera of 100 schoolchildren with at least one intestinal nematode and/or a positive serological reaction for anti-Toxocara antibodies and in 95 schoolchildren without intestinal helminthiasis or serum anti-Toxocara antibodies. Both groups were from public elementary schools located on the urban periphery of Vitoria, ES, ... Read More »
» Published in Rev Soc Bras Med Trop. 2007 Mar-Apr;40(2):147-51.

37. A case of pelvic bone hydatidosis--diagnosis and treatment.
Match Strength: 3.825

INTRODUCTION: Echinococcosis is a frequent helminthiasis in Bulgaria. Hydatid cysts commonly affect the liver and the lung. Echinococcosis rarely involves bones (0.5 to 2.5%) and vertebral column is affected in 50% of the cases. PATIENTS AND METHODS: We report a case of a 67-year-old female with echinococcosis of the pelvic bone clinically manifested by pain and swelling of the right iliac region and complicated by abscess of the surrounding soft tissue. The patient underwent surgery at the Department of Orthopedics and Traumatology, University hospital "St. George", Medical University, ... Read More »
» Published in Folia Med (Plovdiv). 2006;48(1):60-3.

38. Effect of administration of intestinal anthelmintic drugs on haemoglobin: systematic review of randomised controlled trials.
Match Strength: 3.808

OBJECTIVE: To evaluate the effect of routine administration of intestinal anthelmintic drugs on haemoglobin. DESIGN: Systematic review of randomised controlled trials. DATA SOURCES: Electronic databases and hand search of reviews, bibliographies of books, and abstracts and proceedings of international conferences. STUDY SELECTION: Included studies were randomised or quasi-randomised controlled trials using an intestinal anthelmintic agent in the intervention group, in which haemoglobin was evaluated as an outcome measure. Trials in which treatment for schistosoma (praziquantel) was given ... Read More »
» Published in BMJ. 2007 May 26;334(7603):1095. Epub 2007 Apr 13. Comment in: BMJ. 2007 Jun 9;334(7605):1180., BMJ. 2007 May 26;334(7603):1065-6.

39. Prevalence of multiple intestinal helminths among children in a rural community.
Match Strength: 3.785

Impairment of physical and mental development has been identified as deleterious effects of helminthic infection. As a result, there have been concerted efforts to control this group of diseases especially among children who are most vulnerable. However, knowing the prevalence of multiple infections will strengthen or otherwise justify the use of broad spectrum antihelminthics in the prophylaxis and treatment of intestinal helminthes among children. This study was carried out in a farming community with no tarred access road, electricity or pipe-borne water. The diagnosis of intestinal ... Read More »
» Published in Afr J Med Med Sci. 2005 Sep;34(3):263-7.

40. Adverse reactions of 300 MG diethylcarbamazine, and in a combination of 400 MG albendazole, for a mass annual single dose treatment, in migrant workers in Phang Nga province.
Match Strength: 3.621

BACKGROUND: Foreign migrant workers with work permits in Thailand are given once a year 300 mg diethyl-carbamazine (DEC) for bancroftian filariasis, and 400 mg albendazole (ABZ) for helminthiasis. Treatment effectiveness, tolerability, and safety of two treatment arms, DEC + ABZ and DEC alone, had never been fully documented. OBJECTIVE: Evaluate the tolerability of the two treatment arms and analyze the effects of adverse reaction, prevalence, and intensity of both common and uncommon adverse drug reactions (ADR) in relation to the reaction time (2 hours = acute, > 2 to 24 hours = subacute, ... Read More »
» Published in J Med Assoc Thai. 2007 Mar;90(3):552-63.

41. Risk factors for Schistosoma mansoni and hookworm in urban farming communities in western Cote d'Ivoire.
Match Strength: 3.583

OBJECTIVES: To identify risk factors for Schistosoma mansoni and hookworm infections in urban farming communities, and to investigate small-scale spatial patterns of infection prevalence. METHODS: A cross-sectional survey was carried out in 113 farming households (586 individuals) and 21 non-farming households (130 individuals) from six agricultural zones in the town of Man, western Cote d'Ivoire. Heads of households were interviewed on common agricultural activities, land and water use, education attainment, socioeconomic status and sanitation facilities. Household members provided stool ... Read More »
» Published in Trop Med Int Health. 2007 Jun;12(6):709-23.

42. Renal medullary AA amyloidosis, hepatocyte dissociation and multinucleated hepatocytes in a 14-year-old free-ranging lioness (Panthera leo).
Match Strength: 3.448

A 14-year-old lioness, originating from Etosha in Namibia, and a member of a pride in Pilanesberg National Park since translocation in 1994, was euthanased due to fight-related vertebral fracture and spinal injury, incurred approximately 6-8 weeks previously. Blood specimens collected at the time of death showed mild anaemia and a leukogram reflecting stress and chronic infection. Necropsy conducted within 2 hours of death was on a dehydrated, emaciated animal with hindquarter wasting and chronic traumatic friction injuries from dragging her hindlegs. There was cellulitis in the region of bite ... Read More »
» Published in J S Afr Vet Assoc. 2005 Jun;76(2):90-8.

43. Efficacy of a single-dose treatment with 300 mg diethylcarbamazine and a combination of 400 mg albendazole in reduction of Wuchereria bancrofti antigenemia and concomitant geohelminths in Myanmar migrants in Southern Thailand.
Match Strength: 3.282

BACKGROUND: There seems to be a large magnitude of parasitic worm loads caused by nocturnally periodic Wuchereria bancrofti and geohelminths, in cross-border Myanmar migrant workers in Thailand. We are therefore considering an effective Mass Drug Administration (MDA) with Diethylcarbamazine (DEC) and Albendazole (ABZ). Due to short periods of their residency and current situation of W. bancrofti antigenemics and concomitant geohelminths, treatment effects on the containment of the infections need to be analyzed. OBJECTIVES: Analyze short-term effects on reduction of W. bancrofti antigen (WbAg) ... Read More »
» Published in J Med Assoc Thai. 2006 Aug;89(8):1237-48.

44. Recall of intestinal helminthiasis by HIV-infected South Africans and avoidance of possible misinterpretation of egg excretion in worm/HIV co-infection analyses.
Match Strength: 3.230

BACKGROUND: Ascariasis and HIV/AIDS are often co-endemic under conditions of poverty in South Africa; and discordant immune responses to the respective infections could theoretically be affecting the epidemic of HIV/AIDS in various ways. It is well-known that sensitisation to helminthic antigens can aggravate or ameliorate several non-helminthic diseases and impair immunisation against cholera, tetanus and tuberculosis. The human genotype can influence immune responses to Ascaris strongly. With these factors in mind, we have started to document the extent of long-term exposure to Ascaris and ... Read More »
» Published in BMC Infect Dis. 2006 May 26;6:88.

45. Prevalence and seasonal changes in the population of gastrointestinal nematodes of small ruminants in the semi-arid zone of north-eastern Nigeria.
Match Strength: 3.200

A survey was carried out to determine the prevalence and seasonal abundance of the egg and adult stages of nematode parasites of sheep and goats in the semi-arid zone of north-eastern Nigeria between January and December 2002. Faecal samples collected from 102 sheep and 147 goats and examined by the modified McMaster technique using saturated solution of sodium chloride as the floating medium revealed that 44 (43.1%) and 82 (55.8%) of the samples, respectively, contained at least one nematode egg type. Three nematode egg types were recovered with strongyle egg type (22.5% in sheep and 35.4% in ... Read More »
» Published in Vet Parasitol. 2007 Mar 15;144(1-2):118-24. Epub 2006 Nov 28.

46. Placental umbilical cord whole blood transfusion to combat anemia in the background of advanced rheumatoid arthritis and emaciation and its potential role as immunoadjuvant therapy.
Match Strength: 2.699

Rheumatoid arthritis is the commonest form of inflammatory arthritis and affects about 1-3% of the population in the West and even more in the developing world due to the compounded factors of late detection and inadequate treatment in the overall background of poverty, deprivation, and improper macro and micronutrients in the diet in a sizeable segment of the population. Nearly 90% of patients with aggressive disease will become clinically disabled within 20 years. Furthermore, in patients with severe disease or extra-articular symptoms, mortality is equal to that for patients with triple ... Read More »
» Published in Clin Exp Obstet Gynecol. 2006;33(1):28-33.

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