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Heart Disease Ischemic
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1. Recent increase of neighborhood socioeconomic effects on ischemic heart disease mortality: a multilevel survival analysis of two large Swedish cohorts.
Match Strength: 10.936

Studies have shown that the decrease in ischemic heart disease mortality over the past decades was paralleled by an increase in socioeconomic disparities. Using two large Swedish cohorts defined in 1986 and 1996, the authors examined whether the effect of neighborhood socioeconomic position on ischemic heart disease mortality strengthened over the period and whether the relative contribution of individual and neighborhood socioeconomic effects changed over time. Multilevel survival models adjusted for individual factors indicated that neighborhood socioeconomic effects on ischemic heart ... Read More »
» Published in Am J Epidemiol. 2007 Jan 1;165(1):22-6. Epub 2006 Sep 14.

2. Subsets of SNPs define rare genotype classes that predict ischemic heart disease.
Match Strength: 7.601

Single nucleotide polymorphisms (SNPs) are hypothesized to explain the genetic predisposition to ischemic heart disease (IHD) in the general population. Lack of evidence for a role of such variation is fostering pessimism about the utility of genetic information in the practice of medicine. In this study we determined the utility of exonic and 5' SNPs in apolipoprotein E (APOE) and lipoprotein lipase (LPL) when considered singly and in combination for predicting incidence of IHD in 8,456 individuals from the general population during 24 years of follow-up. In men, LPL D9N improved prediction ... Read More »
» Published in Hum Genet. 2007 Feb;120(6):865-877. Epub 2006 Sep 28.

3. Cardiovascular disease and risk factors in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis.
Match Strength: 5.947

OBJECTIVE: To compare the prevalence of cardiovascular diseases and their risk factors between patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS) and control subjects. METHODS: Data for patients continuously enrolled in an integrated outcomes database between January 1, 2001, and December 31, 2002, with International Classification of Diseases, 9th Revision codes of 714.x (RA), 696.0 (PsA), or 720.0 (AS) were evaluated in this cross-sectional comparative study. Control groups were established for each patient group (1:4 ratio) by matching on the ... Read More »
» Published in J Rheumatol. 2006 Nov;33(11):2167-72. Epub 2006 Sep 1. Comment in: J Rheumatol. 2006 Nov;33(11):2105-7.

4. Mitral Valve Annuloplasty With Carpentier-Edwards Physio Ring: Mid-term Results.
Match Strength: 5.831

The mid-term results of mitral valve repair with the Carpentier-Edwards Physio annuloplasty ring were assessed in 97 consecutive patients in a single tertiary-referral cardiothoracic surgical center. The mean follow-up time was 3.9 years (range, 1 month to 8.9 years). Most patients were in functional class II and III before the operation. Ejection fraction was < 40% in 8 patients. Causes of mitral regurgitation included degenerative disease (66%), infective endocarditis (13.4%), rheumatic disease (10.3%), and ischemic heart disease (9.3%). Thirty-day mortality was 2.1%. Actuarial survival ... Read More »
» Published in Asian Cardiovasc Thorac Ann. 2006 Oct;14(5):382-6.

5. Prognostic value of myocardial perfusion contrast echocardiography in patients with suggested or known ischemic heart disease.
Match Strength: 5.763

OBJECTIVE: We sought to determine the prognostic value of myocardial contrast echocardiography (MCE) in patients with known or suggested coronary artery disease compared with technetium-99m sestamibi single photon emission computed tomography (SPECT)-myocardial perfusion imaging (MPI). BACKGROUND: The prognostic value of SPECT-MPI is well established for patients with coronary artery disease. It is less well defined by MCE. METHODS: In all, 51 consecutive patients with suggested coronary artery disease prospectively underwent MCE and SPECT-MPI at baseline and after dipyridamole infusion. MCE ... Read More »
» Published in J Am Soc Echocardiogr. 2006 Oct;19(10):1203-10.

6. The effects of carbenoxolone on human myocardial conduction: a tool to investigate the role of gap junctional uncoupling in human arrhythmogenesis.
Match Strength: 5.213

OBJECTIVES: This study assessed the effects of carbenoxolone on human myocardial conduction and refractoriness. BACKGROUND: Carbenoxolone, an antipeptic ulcer drug, has been shown to reduce gap junctional coupling without affecting cellular ion channels. Gap junctions (GJ) are considered to be determinants of cardiac action potential propagation. The effects of GJ uncoupling in the human heart are unknown. METHODS: Right atrial (RA) and ventricular (RV) activation mapping (Carto, Biosense Webster Inc., Diamond Bar, California) was performed during sinus rhythm. Right atrial and RV wavefront ... Read More »
» Published in J Am Coll Cardiol. 2006 Sep 19;48(6):1242-9. Epub 2006 Aug 28.

7. Clinical observation on effect of Kaixin capsule in treating 40 patients with diabetic myocardial ischemia.
Match Strength: 4.644

OBJECTIVE: To observe the effect of Kaixin Capsule (KXC) on myocardial ischemia and plasma endothelin (ET) level in patients with diabetic heart disease (DHD). METHODS: The 72 subjects for observation were randomly selected from inpatients whose diagnosis fit to the standard of DHD. The 32 patients allocated in the control group were treated with conventional Western medicine, and the 40 patients in the treated group were treated with conventional Western medicine in combination with KXC, with the therapeutic course for both groups as 60 days. RESULTS: On ECG, the total effective rate and ... Read More »
» Published in Chin J Integr Med. 2006 Sep;12(3):215-7.

8. Attenuation of the negative inotropic effects of metoprolol at short cycle lengths in humans: comparison with sotalol and verapamil.
Match Strength: 3.764

OBJECTIVES: This study sought to compare the influence of changes in systolic interval on the negative inotropic effects of metoprolol, sotalol, and verapamil in patients with ischemic heart disease. BACKGROUND: The long-term symptomatic and prognostic effects of antiarrhythmic agents are not easily predicted on the basis of acute hemodynamic actions at rest, but may be unmasked during tachycardia. However, this has not been studied extensively in vivo. METHODS: The force-interval relationship of the intact human left ventricle was examined before and 10 min after intravenous bolus ... Read More »
» Published in J Am Coll Cardiol. 2006 Sep 19;48(6):1234-41. Epub 2006 Aug 28.

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