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Peer Reviewed Scientific Research Reports.
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1. Arterial pulse wave analysis: An accurate means of determining cardiac output in children.
Match Strength: 6.132
OBJECTIVE: Cardiac output is a useful measure of myocardial performance. Standard methods of determining cardiac output are not without risk and can be problematic in children. Arterial pulse wave analysis (PulseCO), a novel, minimally invasive cardiac output determination technique, offers the advantage of continuous monitoring, convenience, and low risk. This technique has not been validated in children. The purpose of this study was to validate PulseCO as an accurate means of noninvasively determining real-time cardiac output in children. DESIGN: Prospective, single-center evaluation. ... Read More »
» Published in Pediatr Crit Care Med. 2006 Nov;7(6):532-5.
2. Pulmonary arterial hypertension and rheumatic diseases--from diagnosis to treatment.
Match Strength: 4.614
Survival rates in pulmonary arterial hypertension (PAH) associated with rheumatic diseases, in particular connective tissue diseases such as systemic sclerosis, are even lower than in idiopathic PAH. These low survival rates highlight the need for early diagnosis and treatment in these patients. Transthoracic Doppler-echocardiography is most often used for diagnostic screening of patients at risk. Other screening tests are serum pro-brain-natriuretic peptide (pro-BNP) and diffusion capacity for carbon monoxide (DLCO), which appear to be changed early in the course of the PAH associated with ... Read More »
» Published in Rheumatology (Oxford). 2006 Oct;45 Suppl 4:iv22-iv25.
3. Does cyclically iloprost infusion prevent severe isolated pulmonary hypertension in systemic sclerosis? Preliminary results.
Match Strength: 3.729
The objective of this study was to present our clinical experience about scleroderma-related pulmonary hypertension in the patients treated with intermittent iloprost infusions. Eighty-one patients affected by systemic sclerosis (12 men, 69 women; 30 with diffuse pattern and 51 with limited pattern; mean age 55.1 years; mean duration of disease 105.3 months) have been treated with cyclic iloprost infusions for at least 15 months (range 15-126 months). During the last 4 months all patients underwent Doppler echocardiography in order to estimate the value of systolic pulmonary artery pressure. ... Read More »
» Published in Rheumatol Int. 2006 Dec;27(2):203-5. Epub 2006 Sep 28.
4. Attenuation of the negative inotropic effects of metoprolol at short cycle lengths in humans: comparison with sotalol and verapamil.
Match Strength: 3.605
OBJECTIVES: This study sought to compare the influence of changes in systolic interval on the negative inotropic effects of metoprolol, sotalol, and verapamil in patients with ischemic heart disease. BACKGROUND: The long-term symptomatic and prognostic effects of antiarrhythmic agents are not easily predicted on the basis of acute hemodynamic actions at rest, but may be unmasked during tachycardia. However, this has not been studied extensively in vivo. METHODS: The force-interval relationship of the intact human left ventricle was examined before and 10 min after intravenous bolus ... Read More »
» Published in J Am Coll Cardiol. 2006 Sep 19;48(6):1234-41. Epub 2006 Aug 28.
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