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Gastroparesis
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1. A large splenic cyst mimicking diabetic gastroparesis.
Match Strength: 8.368

Splenic cysts are rare, many of which are asymptomatic and incidental finding. We report an interesting case of a large incidental splenic cyst in a young diabetic patient who presented with diabetic ketoacidosis and mimicking gastroparesis. The differential diagnosis and management of splenic cysts is discussed ... Read More »
» Published in Int J Clin Pract. 2006 Oct;60(10):1317-8.

2. Relief of acute pain in chronic idiopathic gastroparesis with intravenous phentolamine.
Match Strength: 7.729

OBJECTIVE: To report a case in which complete relief of pain associated with gastroparesis, with promotion of gastric emptying, was achieved with administration of phentolamine. CASE SUMMARY: A 37-year-old opiate-tolerant female with a history of recurrent abdominal pain, gastroparesis, cyclic vomiting syndrome, and migraine headaches was admitted to the emergency department (ED) with severe acute abdominal pain, nausea, and vomiting. The patient had been previously implanted with a permanent gastric electrical stimulator and she was adherent to her prokinetic, antiemetic, analgesic, and ... Read More »
» Published in Ann Pharmacother. 2006 Nov;40(11):2032-6. Epub 2006 Sep 26.

3. Making a case for domperidone in the treatment of gastrointestinal motility disorders.
Match Strength: 7.434

There are very few treatment options currently available for patients with gastrointestinal motility disorders, especially patients with gastroparesis. Domperidone, a peripheral dopamine receptor antagonist, has been successfully used for decades in the US and marketed in many countries for the treatment of gastroparesis. Its use, however, has recently become controversial owing to safety concerns, and it has never been approved for marketing by the FDA. During the 1990s, domperidone was available to US gastroenterologists under a compassionate-use program by Janssen Pharmaceutica, as the ... Read More »
» Published in Curr Opin Pharmacol. 2006 Dec;6(6):571-6. Epub 2006 Sep 25.

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