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Peer Reviewed Scientific Research Reports.
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1. Altered skin blood perfusion in areas with non blanchable erythema: an explorative study.
Match Strength: 9.026
Non blanchable erythema, i.e. stage I pressure ulcer, is common in patients in acute and geriatric care and in nursing homes. Research has shown that this type of lesions is prone to develop into more severe pressure ulcers. The peripheral skin blood perfusion is of major importance for the development of pressure ulcers. The aim of this study was to explore the peripheral skin blood perfusion over time, in areas with non blanchable erythema and in corresponding undamaged areas on the opposite side of the body. A total of 19 measurements were performed, over time, using a laser Doppler ... Read More »
» Published in Int Wound J. 2006 Sep;3(3):215-23.
2. Painful rash and swelling of the limbs after recurrent infections in a teenager: polyarteritis nodosa.
Match Strength: 6.326
Polyarteritis nodosa is a rare disease in childhood and adolescence that is difficult to diagnose clinically. We report on a 17-y-old girl presenting with a history of recurrent infections of the upper respiratory tract and conjunctivitis followed by a painful rash on the upper and lower extremities resembling erythema nodosum. The diagnosis of polyarteritis nodosa was proven by skin biopsy. Therapy with intravenous immunoglobulins failed, but with systemic steroids she responded promptly. CONCLUSION: Polyarteritis nodosa is a differential diagnosis in adolescents presenting with fever and an ... Read More »
» Published in Acta Paediatr. 2006 Oct;95(10):1317-20.
3. A randomised controlled trial of the effect of biphasic or monophasic waveform on the incidence and severity of cutaneous burns following external direct current cardioversion.
Match Strength: 6.004
OBJECTIVE: Cutaneous burns are a common cause of morbidity following direct current (DC) cardioversion. We designed a prospective randomised double-blinded controlled study to determine the effect of biphasic or monophasic waveform on the pain and inflammation occurring after elective cardioversion. MATERIALS AND METHODS: One hundred and thirty nine patients undergoing elective DC cardioversion were randomised to receive monophasic (HP Codemaster XL; 100, 200, 300, 360, and 360 J) or biphasic (Welch Allyn-MRL PIC defibrillator; 70, 100, 150, 200, and 300 J) waveforms. Two hours after DC ... Read More »
» Published in Resuscitation. 2006 Dec;71(3):293-300. Epub 2006 Sep 20.
4. An evaluation on the efficacy and safety of amlexanox oral adhesive tablets in the treatment of recurrent minor aphthous ulceration in a Chinese cohort: a randomized, double-blind, vehicle-controlled, unparallel multicenter clinical trial.
Match Strength: 5.647
OBJECTIVE: The objectives of this study were to clinically determine the topical efficacy and safety of amlexanox oral adhesive tablets in the treatment of recurrent minor aphthous ulcerations (MiRAU) in a Chinese cohort. STUDY DESIGN: A randomized, double-blind, vehicle-controlled, unparallel multicenter clinical trial was carried out. The tablets were applied by subjects themselves 4 times a day for 5 days. Four parameters (pain scale, size change, degree of erythema and exudation, and efficacy index) were recorded both before (baseline) and during the trial (on the morning of days 4 and 6). ... Read More »
» Published in Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Oct;102(4):475-81. Epub 2006 Jun 19.
5. Photoadaptation: a path toward rational phototherapy protocols.
Match Strength: 4.685
Photoadaptation is defined as the diminished future response to equivalent doses of irradiation. It is most often estimated in vivo by looking at changes in the minimal erythema dose with subsequent doses of UV radiation. Although photoadaptation's mechanism of action is poorly understood, Palmer et al. help clarify the clinical significance of photoadaptation for the dosimetry of UV-based phototherapy. Publication Types: ... Read More »
» Published in J Invest Dermatol. 2006 Oct;126(10):2156-8. Comment on: J Invest Dermatol. 2006 Jun;126(6):1256-63.
6. A double-blind, vehicle-controlled clinical study to evaluate the efficacy of MAS065D (XClair), a hyaluronic acid-based formulation, in the management of radiation-induced dermatitis.
Match Strength: 4.464
This study was designed to assess the efficacy and tolerability of MAS065D (Xclair) compared to a vehicle control in the management of radiation dermatitis in patients receiving radiotherapy for breast cancer. Twenty patients were randomized blindly to use the two study substances, three times daily, on separate sections of irradiated skin throughout the duration of radiotherapy and for two weeks afterwards. Patients were monitored before therapy, weekly during therapy, and for 2 weeks after radiotherapy was completed. Skin appearance according to National Cancer Institute (NCI) toxicity ... Read More »
» Published in Cutan Ocul Toxicol. 2006;25(3):165-71.
7. Localised sarcoptic mange in dogs: a retrospective study of 10 cases.
Match Strength: 3.770
The authors report 10 cases of localised sarcoptic mange in dogs. In each case, lesions were localised to one precise area of the skin. Pruritus was present in nine cases and absent in one. Affected areas were the feet (one case), the face and/or the pinnae (six cases), the abdominal skin (one case), the flank (one case) and the lumbar area (one case). The types of lesions were erythema, papules, lichenification, scales, crusts and alopecia. Parasites were found in all cases except one, in which anti-immunoglobulin G Sarcoptes serology was positive. The acaricidal treatments given were lindane ... Read More »
» Published in J Small Anim Pract. 2006 Oct;47(10):611-4.
8. Hair removal for Fitzpatrick skin types V and VI using light and heat energy technology.
Match Strength: 3.087
OBJECTIVE: To determine the safety and efficacy of a light and heat energy (LHE)-based system (SkinStaion system; Radiancy Inc, Orangeburg, NY, USA) for hair removal in subjects with skin types V and VI. METHODS: Thirty-one subjects with Fitzpatrick skin types V and VI were consented for treatment with the system. Twenty-six subjects completed the 12-week follow-up. Safety was evaluated at each visit and efficacy was evaluated at both follow-up visits. RESULTS: An average hair clearance of 41.7% from 57 treatment sites was reported at the 6-week follow-up visit and a 35.5% average hair ... Read More »
» Published in J Drugs Dermatol. 2006 Sep;5(8):724-6.
9. The Overlap of Sjogren's Syndrome with Other Systemic Autoimmune Diseases.
Match Strength: 2.692
OBJECTIVE: To analyze the main diagnostic problems caused by the overlap between Sjogren's syndrome (SS) and other systemic autoimmune diseases (SAD). METHODS: We performed a MEDLINE search for articles published between January 1966 and December 2005 that specifically analyzed the overlap between SS and other SAD. We identified a list of diagnostic problems in patients with primary SS who had features considered typical of other SAD. RESULTS: Clinically, the main diagnostic problems occur in SS patients presenting with arthritis, Raynaud phenomenon, cutaneous features (subacute cutaneous ... Read More »
» Published in Semin Arthritis Rheum. 2007 Feb;36(4):246-255. Epub 2006 Sep 22.
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