Endocrine Gland Cancer
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Peer Reviewed Scientific Research Reports.
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1. Fetal origins of breast cancer.
Match Strength: 6.885
Susceptibility to breast cancer might be pre-determined in utero. Alterations in the fetal hormonal environment, caused by either maternal diet or exposure to environmental factors with endocrine activities, can modify the epigenome, and these modifications are inherited in somatic daughter cells and maintained throughout life. These epigenetic modifications might lead to changes in mammary gland development, such as increased vulnerability of epithelial targets for malignant transformation. According to this hypothesis, on post-pubertal exposure to an initiating factor, such as a carcinogen, ... Read More »
» Published in Trends Endocrinol Metab. 2006 Nov;17(9):340-8. Epub 2006 Sep 25.
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