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EBV Infections
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1. Multilocus-sequence typing analysis reveals similar populations of Streptococcus uberis are responsible for bovine intramammary infections of short and long duration.
Match Strength: 5.196

Multilocus-sequence typing (MLST) was used to analyse Streptococcus uberis isolates from a single herd associated with long duration (50-260 days) and rapidly cleared (less than 1 month) bovine intramammary infections to determine whether the bacterial type had any impact on the duration of infection. Most chronic infections (24 of 33) were due to continuous infection of the mammary quarter with the same sequence type, and infections were found to persist for many months. The remaining quarters were re-infected with a different sequence type within a single lactation. No particular sequence ... Read More »
» Published in Vet Microbiol. 2007 Jan 31;119(2-4):194-204. Epub 2006 Aug 17.

2. Emerging fungi.
Match Strength: 4.928

The hyalohyphomycetes (especially Fusarium spp) have emerged as significant pathogens in severely immunocompromised patients. Human infections by Fusarium spp can be superficial or limited to single organs in otherwise healthy patients. Such infections are rare and tend to respond well to therapy. By contrast, disseminated fusarial hyalohyphomycosis affects the immunocompromised host and frequently is fatal. Successful outcome is determined by the degree of immunosuppression and the extent of the infection. These infections may be suspected clinically on the basis of a constellation of ... Read More »
» Published in Infect Dis Clin North Am. 2006 Sep;20(3):563-79.

3. Periodontal infections and atherosclerotic vascular disease: an update.
Match Strength: 4.668

The role of periodontal infections as a putative risk factor for atherosclerotic vascular disease (ASVD) has been reported in the literature over the past decade. This review provides insights into biologically plausible pathways that can potentially mediate such an association, and discusses recent findings from epidemiological studies and intervention trials. Accumulating epidemiological evidence suggests that clinical, microbiological and serological markers of periodontal infection are associated with subclinical and manifest ASVD. Early evidence from intervention studies suggests that the ... Read More »
» Published in Int Dent J. 2006 Aug;56(4 Suppl 1):256-62.

4. Zoonotic infections among veterinarians in Turkey: Crimean-Congo hemorrhagic fever and beyond.
Match Strength: 4.556

OBJECTIVES: We aimed to determine the seroprevalence of Crimean-Congo hemorrhagic fever (CCHF) virus, Brucella spp, and Coxiella burnetii among veterinarians in a highly endemic and a non-endemic region for these infections in Turkey. METHODS: The antibody levels against these three infections were surveyed. Eighty-three veterinarians were included from two distinct geographic regions. RESULTS: CCHF IgG positivity (3% vs. 0%) and Brucella agglutination titer of > or =1/160 (33% vs. 5%) were more common in the endemic region, whereas the rates of Coxiella burnetii antibodies were similar (7% ... Read More »
» Published in Int J Infect Dis. 2006 Nov;10(6):465-9. Epub 2006 Sep 15.

5. Communicable respiratory threats in the ED: tuberculosis, influenza, SARS, and other aerosolized infections.
Match Strength: 4.373

Respiratory infections are the most common communicable infectious diseases. EDs are the front line for patients with respiratory infections because of their acute nature and because the ED is the principal site of health care for those at highest risk. These diseases include influenza, tuberculosis, and measles, together accounting for 25% of infectious causes of death worldwide. These are emerging and biothreat agents that follow the same route of transmission, such as pneumonic plague. We discuss epidemiology, pathogenesis, diagnosis, and treatment of each agent. Emphasis is on the ED's ... Read More »
» Published in Emerg Med Clin North Am. 2006 Nov;24(4):989-1017.

6. Mendelian resistance to human norovirus infections.
Match Strength: 4.332

Noroviruses have emerged as a major cause of acute gastroenteritis in humans of all ages. Despite high infectivity of the virus and lack of long-term immunity, volunteer and authentic studies has suggested the existence of inherited protective factors. Recent studies have shown that histo-blood group antigens (HBGAs) and in particular secretor status controlled by the alpha1,2fucosyltransferase FUT2 gene determine susceptibility to norovirus infections, with nonsecretors (FUT2-/-), representing 20% of Europeans, being highly resistant to symptomatic infections with major strains of norovirus. ... Read More »
» Published in Semin Immunol. 2006 Dec;18(6):375-86. Epub 2006 Sep 14.

7. Five-year surveillance of nosocomial infections in Ankara Training and Research Hospital.
Match Strength: 4.285

The objective of this study was to assess the rate of nosocomial infections (NIs), frequency of nosocomial pathogens and antimicrobial susceptibility changes in a 530-bed hospital over a five-year period. Hospital-wide laboratory-based NI surveillance was performed prospectively between 1999 and 2003. The Centers for Disease Control and Prevention's definitions were used for NIs and nosocomial surgical site infections, and NI rates were calculated by the number of NIs per number of hospitalized patients on an annual basis. NI rates ranged between 1.4% and 2.4%. Higher rates were observed in ... Read More »
» Published in J Hosp Infect. 2006 Dec;64(4):391-6. Epub 2006 Sep 18.

8. Chlamydia and Mycoplasma serology in respiratory tract infections of children.
Match Strength: 4.267

One of the challenges in planning the treatment of respiratory tract infection in children is identifying the causative agent. The objective of the present study was to investigate the incidence of Mycoplasma and Chlamydia in the etiology of respiratory tract infections of children. The present study included 100 children, three months to 12 years of age, admitted to the outpatient department of pediatrics with such respiratory symptoms as fever, cough and respiratory distress. Following a detailed clinical history and physical examination, complete blood count, erythrocyte sedimentation rate, ... Read More »
» Published in Tuberk Toraks. 2006;54(3):254-8.

9. Emergence of community-associated methicillin resistant Staphylococcus aureus in Hawaii, 2001-2003.
Match Strength: 4.210

OBJECTIVES: We conducted a retrospective study to determine trends and characteristics of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in Hawaii. METHODS: We reviewed medical records of patients with MRSA infections during July 2001-June 2003 in four healthcare facilities. A case was defined as a patient with MRSA infection (colonization excluded), diagnosed in ambulatory settings or ... Read More »
» Published in J Infect. 2006 Sep 18;

10. Ongoing multistate outbreak of Escherichia coli serotype O157:H7 infections associated with consumption of fresh spinach--United States, September 2006.
Match Strength: 4.168

On September 13, 2006, CDC officials were alerted by epidemiologists in Wisconsin and Oregon that fresh spinach was the suspected source of small clusters of Escherichia coli serotype O157:H7 infections in those states. On the same day, New Mexico epidemiologists contacted Wisconsin and Oregon epidemiologists about a cluster of E. coli O157:H7 infections in New Mexico associated with fresh spinach consumption. Wisconsin public health officials had first reported a cluster of E. coli O157:H7 infections to CDC on September 8. On September 12, CDC PulseNet had confirmed that the E. coli O157:H7 ... Read More »
» Published in MMWR Morb Mortal Wkly Rep. 2006 Sep 29;55(38):1045-6.

11. Active screening in high-risk units is an effective and cost-avoidant method to reduce the rate of methicillin-resistant Staphylococcus aureus infection in the hospital.
Match Strength: 4.153

OBJECTIVE: To evaluate the impact of active screening for methicillin-resistant Staphylococcus aureus (MRSA) on MRSA infection rates and cost avoidance in units where the risk of MRSA transmission is high. METHODS: During a 15-month period, all patients admitted to our adult medical and surgical intensive care units (ICUs) were screened for MRSA nasal carriage on admission and weekly thereafter. The overall rates of all MRSA infections and of nosocomial MRSA infection in the 2 adult ICUs and the general wards were compared with rates during the 15-month period prior to the start of routine ... Read More »
» Published in Infect Control Hosp Epidemiol. 2006 Oct;27(10):1009-17. Epub 2006 Sep 20. Comment in: Infect Control Hosp Epidemiol. 2006 Oct;27(10):999-1003.

12. Toxic shock due to Streptococcus pyogenes in a rhesus monkey (Macaca mulatta).
Match Strength: 4.134

Recent years have seen a worldwide resurgence in serious infections caused by group A streptococci. This group includes Streptococcus pyogenes, one of the most common pathogens among children which causes diverse suppurative infections, such as pharyngitis, as well as nonsuppurative infections with sequelae, such as rheumatoid fever and rheumatic heart disease. S. pyogenes produces several superantigen-like erythrogenic toxins, which are believed to be associated with pyrogenicity, erythromatous skin reactions, and various immunologic and cytotoxic effects. These toxins also can cause ... Read More »
» Published in J Am Assoc Lab Anim Sci. 2006 Sep;45(5):79-82.

13. Molecular epidemiology of norovirus infections in sporadic cases of viral gastroenteritis among children in Northern Italy.
Match Strength: 4.077

Surveillance of norovirus infections in sporadic cases of pediatric gastroenteritis admitted to a main hospital in Northern Italy during a full-year period (2002) showed that noroviruses (10.4%) were the second most common causative viral agent, following rotaviruses (21.1%), and noroviruses (81%) were mostly implicated in mixed infections. The epidemic period of norovirus was September-December, with September and November as months of major prevalence (33.3 and 38.5%, respectively). Six distinct norovirus genotypes were detected (GI.7, GII.1, GII.2, GII.4, GII.7, GII, not assigned named GIIb ... Read More »
» Published in J Med Virol. 2006 Nov;78(11):1486-92.

14. Pediatric tonsillotomy with radiofrequency technique: long-term follow-up.
Match Strength: 4.036

OBJECTIVES: Compare the effects of partial tonsil resection using a radiofrequency technique, tonsillotomy (TT), with total tonsillectomy (TE, blunt dissection) after 1 and 3 years. Compare frequency of relapse in snoring or infections and possible long-term changes in behavior among TT children with those in TE children. METHOD: Ninety-two children (5-15 yr) randomized to TT (n = 49) or TE (n = 43) groups because of obstructive problems with or without recurrent tonsillitis. One year after surgery, general health, degree of obstruction, history of infections, and behavior were investigated ... Read More »
» Published in Laryngoscope. 2006 Oct;116(10):1851-7.

15. The in-vivo antimalarial activities of Uvaria chamae and Hippocratea africana.
Match Strength: 4.032

The antimalarial activities of ethanolic root extracts of two plants used traditionally as malarial remedies in southern Nigeria, Uvaria chamae (Annonaceae) and Hippocratea africana (Hippocrateaceae), were studied in vivo, in mice infected with Plasmodium berghei berghei. The extract of U. chamae, when given orally at 300-900 mg/kg.day, exhibited significant antimalarial activity against both early and established infections. When established infections were treated, the mean survival time of the mice observed with this extract at 900 mg/kg.day was similar to that seen with the positive ... Read More »
» Published in Ann Trop Med Parasitol. 2006 Oct;100(7):585-90.

16. New agents for the treatment of fungal infections: clinical efficacy and gaps in coverage.
Match Strength: 4.007

The incidence of fungal infections has increased globally, and the introduction of the newer triazoles and echinocandin antifungals is a more-than-welcome and long overdue development. In this report, we review the clinical trials evaluating the therapeutic efficacy of these new antifungal agents and examine possible gaps in coverage. Voriconazole has become the primary treatment for most forms of invasive aspergillosis in a number of centers, posaconazole offers a broad antifungal spectrum, and echinocandins are fungicidal against most Candida species. Moreover, the new agents are active ... Read More »
» Published in Clin Infect Dis. 2006 Oct 15;43(8):1060-8. Epub 2006 Sep 8. Erratum in: Clin Infect Dis. 2006 Nov 1;43(9):1232.

17. Pneumocystis: newer knowledge about the biology of this group of organisms in laboratory rats and mice.
Match Strength: 3.926

This review is an update on some of the remarkable advances that have led to greater understanding of Pneumocystis, an important group of rodent pathogens. The author outlines the life cycle of these pulmonic fungi, their taxonomic position, and their nomenclature. He discusses how infections begin and spread in laboratory rodent colonies, and how those infections are inadvertently maintained in barriered breeding colonies. He also addresses the diagnosis of Pneumocystis infection and provides suggestions for the establishment of Pneumocystis-free animal colonies. Publication Types: ... Read More »
» Published in Lab Anim (NY). 2006 Oct;35(9):55-61.

18. Postmortem findings and opportunistic infections in HIV-positive patients from a public hospital in Peru.
Match Strength: 3.821

There is a paucity of HIV autopsy data from South America and none that document the postmortem findings in patients with HIV/AIDS in Peru. The purpose of this autopsy study was to determine the spectrum of opportunistic infections and the causes of mortality in HIV-positive patients at a public hospital in Lima. Clinico-epidemiological information regarding HIV infection in Peru is also reviewed. Sixteen HIV-related hospital postmortems, performed between 1999 and 2004, were included in this retrospective analysis. The primary cause of death was established in 12 patients: one died of ... Read More »
» Published in Pathol Res Pract. 2006;202(11):767-75. Epub 2006 Sep 19.

19. Human papillomavirus type distribution in cervical cancer in Delhi, India.
Match Strength: 3.750

This hospital-based study in New Delhi, North India was performed to evaluate the prevalence of human papillomavirus (HPV) in cases of invasive cervical carcinoma (ICC). A total of 10 cases presenting with an obvious cervical growth were included in this study. 108 cases that was shown to be ICC on histology (101 squamous cell carcinomas, 4 adenocarcinomas, and one neuroendocrine carcinoma) were included in the analysis. DNA was extracted from tumor tissue and HPV genotype was determined by a consensus PCR assay using a reverse line blot hybridization assay. Of 106 evaluable cases, 104 (98.1%) ... Read More »
» Published in Int J Gynecol Pathol. 2006 Oct;25(4):398-402.

20. Stenotrophomonas maltophilia resistant to trimethoprim-sulfamethoxazole: an increasing problem.
Match Strength: 3.729

Stenotrophomonas maltophilia (S. maltophilia) has recently emerged as an important nosocomial pathogen. Treatment of invasive infections caused by this organism is difficult as the bacterium is frequently resistant to a wide range of commonly used antimicrobials. Trimethoprim-sulfamethoxazole (TMP - SXT) is recommended as the agent of choice for the treatment of S. maltophilia infections. However, the development of resistance to this antibiotic represents a real challenge to laboratorians and clinicians.This letter describes the first isolation of S. maltophilia resistant to TMP - SXT from ... Read More »
» Published in Ann Clin Microbiol Antimicrob. 2006 Sep 18;5:23.

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