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Peer Reviewed Scientific Research Reports.
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1. Risk of oesophageal cancer by histology among patients hospitalised for gastroduodenal ulcers.
Match Strength: 7.945
OBJECTIVE: The mechanism behind the epidemiologically evident inverse relationship between Helicobacter pylori seropositivity and risk of oesophageal adenocarcinoma (OAC) remains obscure. Severe corpus gastritis is unlikely to be in the causal pathway. With the hypothesis of a uniformly low risk, we aimed to explore the associations of OAC with duodenal ulcer (DU) and gastric ulcer (GU) - both linked to H. pylori infection but with different patterns of bacterial colonization and intragastric acidity. We also addressed possible associations of oesophageal squamous cell carcinoma (OSCC) with ... Read More »
» Published in Gut. 2006 Sep 27;
2. Protective effects of nedocromil sodium and sodium cromoglycate on gastroduodenal ulcers: a comparative study in rats.
Match Strength: 7.308
Stabilization of mast cells plays a key mechanism to protect gastrointestinal tract from injury. This study presents a comparative evaluation of mast cell stabilizers nedocromil sodium (NDS) and sodium cromoglycate (SCG) in experimental gastric and duodenal ulcers in rats. Wistar rats of either sex were used in this study. Both NDS and SCG, in the doses of 10, 30 and 100 mg/kg were given intraperitoneally for gastric secretion studies and by gavage for antiulcer studies. Acid secretion studies were undertaken in pylorus-ligated rats. Gastric lesions were induced by water immersion restraint ... Read More »
» Published in Inflammopharmacology. 2006 Aug;14(3-4):163-9.
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