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Peer Reviewed Scientific Research Reports.
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1. Neurocognitive differential diagnosis of dementing diseases: Alzheimer's Dementia, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder.
Match Strength: 6.388
Similarities in presentation of Dementia of Alzheimer's Type, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder, pose differential diagnosis challenges. The current study identifies specific neuropsychological patterns of scores for Dementia of Alzheimer's Type, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder. Neuropsychological domains directly assessed in the study included: immediate memory, delayed memory, confrontational naming, verbal fluency, attention, concentration, and executive functioning. The results reveal specific ... Read More »
» Published in Int J Neurosci. 2006 Nov;116(11):1271-93.
2. Autoimmune pancreatitis associated with a large pancreatic pseudocyst.
Match Strength: 5.870
Pancreatic cystic lesions comprise various entities with different histopathological characteristics and their differential diagnosis is often a challenge for clinicians. Autoimmune pancreatitis (AIP) is usually not considered in the differential diagnosis of cystic lesions, but often mimics the morphological aspects of pancreatic neoplasm. We report the case of a 64-year-old male patient with a cystic pancreatic head lesion (diameter 5 cm) and stenosis of the distal bile duct requiring repeated stenting. Because of the clinical presentation together with moderate elevation of serum CA19-9 and ... Read More »
» Published in World J Gastroenterol. 2006 Sep 28;12(36):5904-6.
3. Geriatric chorea.
Match Strength: 5.525
The differential diagnosis, diagnostic evaluation, and treatment of late-onset chorea are reviewed. Late-onset chorea is rare and has a heterogeneous causation. A systematic approach to geriatric chorea greatly enhances a correct diagnosis. An accurate diagnosis is important because many causes of chorea are treatable or or, when heritable, may have significant implications for subsequent generations. Most late-onset chorea is either nonlimiting, requiring no treatment, has a spontaneous remission, or responds to medication. In a minority of patients, chorea is medically refractory or ... Read More »
» Published in Clin Geriatr Med. 2006 Nov;22(4):879-97, vii.
4. Parkinson's disease: background, diagnosis, and initial management.
Match Strength: 5.428
Parkinson's disease is a common neurodegenerative disorder associated with aging. After essential tremor, it is the most common movement disorder of the elderly. Parkinson's disease is the most common disabling movement disorder. This article reviews the major clinical features, differential diagnosis, approach to diagnosis, and initial management of Parkinson's disease. Publication Types: Research Support, N.I.H., Extramural, Research Support, U.S. Gov't, Non-P.H.S., ... Read More »
» Published in Clin Geriatr Med. 2006 Nov;22(4):735-51, v.
5. CT findings in duodenal diverticulitis.
Match Strength: 5.389
OBJECTIVE: Duodenal diverticulitis is a rare complication of duodenal diverticulosis. It is often clinically misdiagnosed because it has no pathognomonic signs or symptoms and its CT findings may mimic other intraabdominal processes. We describe two patients with duodenal diverticulitis who presented with abdominal pain, nausea, and leukocytosis. At the time of initial presentation, only one of the two patients was diagnosed correctly. In the first case, which was initially misdiagnosed as acute pancreatitis, the correct diagnosis was evident only after the disease process had become more ... Read More »
» Published in AJR Am J Roentgenol. 2006 Oct;187(4):W392-5.
6. Immunohistochemical markers in diagnosis of papillary thyroid carcinoma: Utility of HBME1 combined with CK19 immunostaining.
Match Strength: 5.324
Papillary thyroid carcinoma and its variants can be difficult to distinguish from cellular adenomatous nodules. Prior studies have advocated various antibodies to aid in the differential diagnosis, but there is little agreement on their utility. We undertook this study to evaluate immunohistochemical markers in the diagnosis and differential diagnosis of papillary thyroid carcinoma. Ten cases of papillary thyroid carcinoma were initially stained for HBME1, CK19, fibronectin1, Ki-67, Calretinin, p16, SFTPB and CITED1. Additionally, two previously untested antibodies to molecules that have been ... Read More »
» Published in Mod Pathol. 2006 Dec;19(12):1631-7. Epub 2006 Sep 22.
7. Diagnostic pitfalls and accuracy of diagnosis in acute abdominal pain.
Match Strength: 5.314
OBJECTIVE: To identify the differential diagnostic difficulties in acute abdominal pain at the emergency department and during hospitalization. MATERIAL AND METHODS: Patients with abdominal pain lasting for up to 7 days were registered during 1997-2000 and re-evaluated one year after discharge (n=2851). RESULTS: Diagnoses with low sensitivity at the emergency department but markedly increased sensitivity at discharge were non-specific abdominal pain with a sensitivity value at the emergency department of 0.43, appendicitis 0.80, gallstones 0.68, constipation 0.74 and peptic ulcer 0.26. ... Read More »
» Published in Scand J Gastroenterol. 2006 Oct;41(10):1126-31.
8. Electrocardiographical case. Acute severe chest tightness.
Match Strength: 5.272
The early diagnosis of acute myocardial infarction is crucial for the institution of appropriate reperfusion therapy. We describe a 56-year-old man who developed sudden onset of severe chest tightness. Inferior, posterior and right ventricular ST elevation myocardial infarction was diagnosed on electrocardiography (ECG). The ECG interpretation, differential diagnosis and management are discussed. Publication Types: Case ... Read More »
» Published in Singapore Med J. 2006 Oct;47(10):913-6; quiz 917.
9. Multiple cardiac inflammatory myofibroblastic tumors in the right ventricle in an infant.
Match Strength: 4.674
Reported is the successful treatment of a 2-month-old boy with multiple inflammatory myofibroblastic tumors in the right ventricle protruding into the right atrium through the tricuspid annulus. The patient underwent subtotal excision on cardiopulmonary bypass with no intraoperative or postoperative complications. Cardiac inflammatory myofibroblastic tumors are rare lesions, and surgical resections in patients as young as 2 months have not been previously described. In this report we review the relevant literature and discuss the prevalence, histology, pathogenesis, clinical manifestations, ... Read More »
» Published in Ann Thorac Surg. 2006 Oct;82(4):1531-5.
10. Diagnosis and management of the dermatologic manifestations of the polycystic ovary syndrome.
Match Strength: 4.630
Polycystic ovary syndrome (PCOS) is a complex phenotypic spectrum of primarily hyperandrogenic signs and symptoms. PCOS is the most common endocrine disturbance to affect women of reproductive years. Although patients affected are often very disturbed by the cutaneous manifestations, including acne, hirsutism, alopecia, obesity, and acanthosis nigricans, the clinical manifestations of PCOS ramify far beyond the skin. PCOS frequently causes menstrual abnormalities and infertility. Insulin resistance is both pathogenic and a cause of numerous serious health consequences. The accurate diagnosis ... Read More »
» Published in Dermatol Ther. 2006 Jul-Aug;19(4):210-23.
11. Suprasellar and intrasellar paragangliomas.
Match Strength: 4.622
Neoplasms of the sellar region are entities with a large differential diagnosis. Although paraganglionic cells have not been demonstrated in the pituitary or adjacent structures, the existence of sellar region paragangliomas is well-documented. To elucidate, in this area the nature of these unusual tumors is relatively difficult. Clinical history, physical examination, radiographic investigation as well as intraoperative gross observation are the same as those of sellar meningioma or pituitary adenoma. Immunohistochemistry, using neuroendocrine markers and electron microscopy are the two ... Read More »
» Published in Clin Neuropathol. 2006 Sep-Oct;25(5):221-6.
12. Confirmatory needle placement technique for scalene muscle block in the diagnosis of thoracic outlet syndrome.
Match Strength: 4.615
Scalene muscle block is often performed to assist with the clinical differentiation of primary sources of pain and weakness in the upper limb when the differential diagnosis includes thoracic outlet syndrome. This presentation offers a simple clinical method to assess needle placement in the scalene muscle before an injection of local anesthetic which, if properly placed, weakens the scalene muscle and often leads to temporary relief of symptoms associated with neurovascular compression. An appropriate scalene block response provides assistance with medical decision making. Publication Types: ... Read More »
» Published in Tech Hand Up Extrem Surg. 2006 Sep;10(3):173-6.
13. Painful rash and swelling of the limbs after recurrent infections in a teenager: polyarteritis nodosa.
Match Strength: 4.540
Polyarteritis nodosa is a rare disease in childhood and adolescence that is difficult to diagnose clinically. We report on a 17-y-old girl presenting with a history of recurrent infections of the upper respiratory tract and conjunctivitis followed by a painful rash on the upper and lower extremities resembling erythema nodosum. The diagnosis of polyarteritis nodosa was proven by skin biopsy. Therapy with intravenous immunoglobulins failed, but with systemic steroids she responded promptly. CONCLUSION: Polyarteritis nodosa is a differential diagnosis in adolescents presenting with fever and an ... Read More »
» Published in Acta Paediatr. 2006 Oct;95(10):1317-20.
14. Small bowel bacterial overgrowth. An underrecognized cause of malnutrition in older adults.
Match Strength: 4.532
Small bowel bacterial overgrowth (SBBO) is an important and under-recognized clinical syndrome in the elderly. It is the most common cause of malabsorption among older adults. Presentation of SBBO syndrome is often occult, which makes it imperative to maintain a high index of suspicion for this disorder. When symptomatic bacterial overgrowth is appropriately identified and treated there can be positive dramatic results. This article discusses the importance of considering a diagnosis of bacterial overgrowth in those predisposed to its development and the mechanisms by which nutrient ... Read More »
» Published in Geriatrics. 2006 Sep;61(9):21-6.
15. Neurosarcoidosis--a diagnostic pitfall with consequences.
Match Strength: 4.519
Neurosarcoidosis is often a diagnostic dilemma, especially in the absence of other organ involvement. We report a 64-year-old patient who had suffered from paraplegia due to an intramedullar process since 1995. The presumptive diagnosis based on computed tomography was spinal cord infarction. Six years later, he complained about increasing paresthesia. Magnetic resonance imaging of the spinal cord showed nodular meningeal enhancement. Computed tomography of the thorax revealed mediastinal and hilar lymphadenopathy. Bronchoscopy under generalized anesthesia was performed. The differential cell ... Read More »
» Published in Wien Klin Wochenschr. 2006 Sep;118(17-18):554-7.
16. The scintigraphic appearance of de Quervain tenosynovitis.
Match Strength: 4.419
PURPOSE: The purpose of this study is to describe the scintigraphic pattern of de Quervain tenosynovitis, a common inflammatory condition of the thumb tendon sheaths related to repetitive use. MATERIALS AND METHODS: The author conducted a retrospective audit of consecutive cases with independent clinical validation of the final diagnosis. RESULTS: There were 7 cases of clinically confirmed de Quervain tenosynovitis. The typical scintigraphic finding was a focal area of superficial linear hyperemia and skeletal uptake along the radial aspect of the distal radius corresponding to the anatomic ... Read More »
» Published in Clin Nucl Med. 2006 Oct;31(10):602-4.
17. Imaging of lipomatous soft tissue tumors.
Match Strength: 4.415
The purpose is to give an overview of the imaging features of benign and malignant lipomatous tumors. Imaging characteristics which are helpful in the differential diagnosis between benign and malignant subtypes are highlighted. Publication Types: ... Read More »
» Published in JBR-BTR. 2006 Jul-Aug;89(4):206-13.
18. Malignant peripheral nerve sheath tumor in oral cavity--a rare site.
Match Strength: 4.379
MPNST occurring in oral cavity, which is a rare site for the tumour, in a 35 year old female patient with history of swelling underneath the tongue present since one year diagnosed clinically as ranula is presented here. Histopathological examination of the excised mass showed features of spindle cell sarcoma following which a provisional diagnosis of MPNST was offered. The differential diagnosis considered were leiomyosarcoma, rhabdomyosarcoma and spindle cell variant of squamous cell carcinoma (being the commoner tumour in oral cavity). Immunohistochemistry confirmed neural origin of the ... Read More »
» Published in Indian J Pathol Microbiol. 2006 Jul;49(3):397-9.
19. Transcutaneous contrast-enhanced sonography of peripheral lung lesions.
Match Strength: 4.348
OBJECTIVE: Transpulmonary sonography contrast agents, in conjunction with contrast-specific imaging techniques, are increasingly accepted in clinical use for diagnostic imaging of several organs. Anatomically, the lung is characterized by dual blood sources, supplied from both the pulmonary and bronchial arteries. Contrast-enhanced sonography enables us to determine whether the pulmonary or the bronchial arteries are the source of blood to lung lesions, depending on the time to enhancement and the extent of enhancement after contrast agent application. CONCLUSION: This article reports our ... Read More »
» Published in AJR Am J Roentgenol. 2006 Oct;187(4):W420-9.
20. Giant cell tumor of the nasal cavity: case report.
Match Strength: 4.157
Soft tissue giant cell tumor of low malignant potential is a rare tumor located in superficial and deep soft tissue. Tumors with osteoclast-like giant cells have been reported in various sites as breast, salivary glands, lung, kidney and pancreas. These tumors are composed of evenly spaced multinucleated giant cells in a background of mononuclear component composed of round, oval or spindled cells. No atypia or significant mitotic activity is encountered. Immunohistochemical stains for TRAP, smooth muscle actin, desmin and cytokeratins are of great value for diagnosis. Nasal cavity represents ... Read More »
» Published in Eur Arch Otorhinolaryngol. 2007 Feb;264(2):205-8. Epub 2006 Sep 15.
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