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Dementia
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1. Frail elderly patients with dementia go too fast.
Match Strength: 9.984

The reason why patients with dementia fall more often and sustain more fractures than patients without dementia remains unclear. Therefore, the relationship between dementia and gait velocity as a marker for mobility and falls in a cohort of frail elderly (mean age of 77.3 years) inpatients was assessed. Patients with dementia were expected to walk slower than patients without dementia. A trend was indeed observed: absolute gait velocity of 0.59 m/s in patients with dementia (n = 63) versus 0.65 m/s in patients without dementia (n = 62; p = 0.19). After adjustment for parkinsonism and walking ... Read More »
» Published in J Neurol Neurosurg Psychiatry. 2006 Jul;77(7):874-6.

2. Family history of dementia: dementia with lewy bodies and dementia in Parkinson's disease.
Match Strength: 9.687

Parkinson's disease with dementia (PD-D) and dementia with Lewy bodies (DLB) may result from the same neurodegenerative process with different temporal and spatial courses. The authors report an association between DLB and family history of dementia in a comparison study between patients with a clinicopathological diagnosis of PD-D and DLB. Findings suggest that positive family history for dementia is associated with DLB with a yet unknown mechanism. Publication Types: Research Support, Non-U.S. Gov ... Read More »
» Published in J Neuropsychiatry Clin Neurosci. 2006 Winter;18(1):113-6.

3. Electroencephalogram in the dementia workup.
Match Strength: 9.637

Dementia is affecting an increasing proportion of the population in the developed world. It is important to reach a correct diagnosis of dementia, because this has implications on the treatment. The electroencephalogram (EEG) is, in general, not a sensitive test for detecting dementia and is not recommended in the standard workup of dementia. In spite of this, however, EEG is useful in patients with deteriorating mental status in whom dementia is suspected mainly to rule out delirium, depression, atypical complex partial seizures, and prion disease. An EEG also provides insight into the ... Read More »
» Published in Am J Alzheimers Dis Other Demen. 2005 May-Jun;20(3):159-66.

4. The role of conventional MR and CT in the work-up of dementia patients.
Match Strength: 9.265

Dementia is a clinical syndrome with many causes. There often is overlap in the clinical manifestations of various forms of dementia, making them difficult to categorize. Neuroimaging can play an important role in distinguishing one form of dementia from another. Advanced imaging techniques continue to provide greater insight into the underlying pathologic processes in patients who have dementia. Conventional MRI and CT, however, still can contribute useful information when interpreting radiologists are familiar with the patterns of volume loss and signal or density changes that are ... Read More »
» Published in Magn Reson Imaging Clin N Am. 2006 May;14(2):169-82. Republished from: Neuroimaging Clin N Am. 2005 Nov;15(4):789-802, x.

5. Quality of life in dementia.
Match Strength: 9.137

There is a growing consensus that quality of life (QOL) is an important outcome for assessing the effectiveness of interventions for dementia, but there is no agreement about how to best measure it. Various approaches to QOL assessment have been employed to measure the QOL of persons with dementia, including patient self-report, caregiver proxy report and observational assessment by trained observers. Furthermore, several dementia-specific measures of QOL have been developed, and several generic measures of QOL have been used to assess QOL in dementia. However, to date, QOL has rarely been ... Read More »
» Published in Can J Neurol Sci. 2007 Mar;34 Suppl 1:S57-61.

6. Towards education-fair dementia screening.
Match Strength: 9.102

The study by Rowland et al. (2006) has shown that the six-item Rowland Universal Dementia Assessment Scale (RUDAS) is as accurate as the MMSE in identifying dementia. A high positive likelihood ratio of RUDAS makes it useful for ruling-in dementia in cases where the disorder is suspected ... Read More »
» Published in Int Psychogeriatr. 2006 Sep 14;:1-2

7. Prevention of falls in older people with dementia.
Match Strength: 9.021

Falls are a major cause of morbidity and mortality in older people with dementia. However, although we know that people with dementia can comply with interventions known to reduce falls in cognitively normal populations, and that these interventions can modify certain risk factors for falls in patients with dementia, direct evidence that falls can be prevented in older people with dementia is lacking. Further research is required specifically targeting fall prevention in older people with dementia ... Read More »
» Published in J Neural Transm. 2007 Jun 8;

8. Supporting people with dementia in acute hospital settings.
Match Strength: 8.998

This article is the first in a series of five focusing on the needs of patients with dementia. The number of people with dementia accessing acute care is rising. The need for acute hospital care to adapt to demographic changes and to reflect these in the acute hospital structure is emphasised. The most common forms of dementia, including Alzheimer's disease, vascular dementia and Lewy body dementia, are discussed. The psychosocial aspects of this condition also need to be considered to promote nursing care that is sensitive to patients' needs. Publication Types: ... Read More »
» Published in Nurs Stand. 2006 Jul 5-11;20(43):51-5.

9. Treatment of vascular dementia: evidence from epidemiologic studies.
Match Strength: 8.941

This article discusses the most relevant recent evidence on the prevention and treatment of vascular dementia from epidemiologic studies. Vascular dementia is the most common form of dementia after Alzheimer's disease and remains the only one that is preventable, although most of our knowledge about primary and secondary prevention of vascular dementia comes from direct extrapolation from works in stroke. Furthermore, at present there are no approved therapeutic agents for the treatment of vascular dementia. Recently, however, a number of reasonable studies on vascular dementia have been ... Read More »
» Published in Curr Treat Options Cardiovasc Med. 2005 Jul;7(3):219-25.

10. Neurocognitive differential diagnosis of dementing diseases: Alzheimer's Dementia, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder.
Match Strength: 8.928

Similarities in presentation of Dementia of Alzheimer's Type, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder, pose differential diagnosis challenges. The current study identifies specific neuropsychological patterns of scores for Dementia of Alzheimer's Type, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder. Neuropsychological domains directly assessed in the study included: immediate memory, delayed memory, confrontational naming, verbal fluency, attention, concentration, and executive functioning. The results reveal specific ... Read More »
» Published in Int J Neurosci. 2006 Nov;116(11):1271-93.

11. Unique problems of dementia in the younger patient.
Match Strength: 8.927

While dementia is often thought of as a problem unique to the elderly patient, nearly one in ten patients with dementia is younger than 65. The etiologies of dementia in this population are varied, including a genetically inherited form of Alzheimer's disease, as well as dementia related to other problems such as Parkinson's disease, Down syndrome, and cerebrovascular disease. Health care practitioners may have difficulty diagnosing early onset dementia because the diagnostic tools and the disease manifestation differ from those of the elderly patient. In addition, treatment of early-onset ... Read More »
» Published in Consult Pharm. 2005 Jun;20(6):468-79.

12. Reducing the burden of dementia in Korea.
Match Strength: 8.905

There has been a dramatic increase in the number of persons with dementia in Korea, and the number is expected to continue to increase. Dementia is increasingly a condition for which there are effective treatments and services. Because most adults work full-time in addition to having other family responsibilities, the government of Korea and the community are more involved in helping persons with dementia, than in the past. Nurses are needed to help with dementia research, public policy, education, and healthcare in Korea and elsewhere ... Read More »
» Published in Nurs Sci Q. 2007 Apr;20(2):178-82.

13. Evolution of HIV dementia with HIV infection.
Match Strength: 8.858

Dementia remains one of the most fearsome complications of HIV infection. It also poses a significant challenge for the clinician both in terms of diagnosis and treatment. The use of antiretroviral agents has led to a decrease in the incidence of HIV dementia but the prevalence of milder forms of neurocognitive impairment has increased. Occasionally, the immune reconstitution caused by these agents may target the brain leading to a syndrome characterized by a severe, progressive and often fatal dementia. The progression of HIV dementia may also be determined by host and viral genetic factors, ... Read More »
» Published in Int Rev Psychiatry. 2008 Feb;20(1):25-31.

14. Vascular dementia: a historical background.
Match Strength: 8.834

The history of vascular dementia can be traced back to cases of dementia postapoplexy described by Thomas Willis in 1672. During most of the 18th and early 19th century, "brain congestion" (due in all likelihood to the effects of untreated hypertension) was the most frequent diagnosis for conditions ranging from stroke to anxiety and to cognitive decline, and bloodletting became the commonplace therapy. The modern history of vascular dementia began in 1894 with the contributions of Otto Binswanger and Alois Alzheimer, who separated vascular dementia from dementia paralytica caused by ... Read More »
» Published in Int Psychogeriatr. 2003;15 Suppl 1:11-3.

15. GP management of dementia - A consumer perspective.
Match Strength: 8.818

As the population ages, the general practitioner is likely to have an increasingly important role in diagnosing and managing dementia.1 Many people in the community dealing with dementia have little help until a diagnosis is made, and their experiences produce a profile of their met and unmet needs. A nondirected interview technique elicits a wide range of themes from individual life phenomena, with each person attributing their own meaning to events and experiences. Open ended discussion can produce unexpected information that is outside the experience of the researcher but relevant to the ... Read More »
» Published in Aust Fam Physician. 2008 Jan-Feb;37(1-2):89-92.

16. The concept of quality of life in dementia in the different stages of the disease.
Match Strength: 8.817

In order to conceptually define quality of life (QOL) in dementia, the literature on QOL in the elderly population, in chronic disease and in dementia was studied. Dementia is a progressive, age-related, chronic condition and to avoid omissions within the dementia-specific concept of QOL, a broad orientation was the preferred approach in this literature study. Adaptation is a major outcome in studies investigating interventions aimed at improving QOL in chronic conditions, but to date, it has not been used in the definition of QOL. It is argued that adaptation is an important indication of QOL ... Read More »
» Published in Int Psychogeriatr. 2005 Sep;17(3):353-70. Comment in: Int Psychogeriatr. 2006 Jun;18(2):357-8; author reply 358-9.

17. Is the dementia rate increasing in Beijing? Prevalence and incidence of dementia 10 years later in an urban elderly population.
Match Strength: 8.770

Objective: To examine the time trend of dementia morbidity over the past decade in Beijing, China. Method: In 1997, 1593 community-dwelling elderly aged 60+ years were examined and followed-up over 2-years to identify incident dementia. A similar cohort study of dementia conducted in the same district 10 years prior was used as historical comparison to examine the time trend of dementia incidence. Results: Forty prevalent dementia cases were identified at the initial examination for a prevalence of 2.51% (95% CI: 1.74-3.28) and 25 incident cases were identified at the follow-up visit for an ... Read More »
» Published in Acta Psychiatr Scand. 2007 Jan;115(1):73-9.

18. Is the dementia rate increasing in Beijing? Prevalence and incidence of dementia 10 years later in an urban elderly population.
Match Strength: 8.770

Objective: To examine the time trend of dementia morbidity over the past decade in Beijing, China. Method: In 1997, 1593 community-dwelling elderly aged 60+ years were examined and followed-up over 2-years to identify incident dementia. A similar cohort study of dementia conducted in the same district 10 years prior was used as historical comparison to examine the time trend of dementia incidence. Results: Forty prevalent dementia cases were identified at the initial examination for a prevalence of 2.51% (95% CI: 1.74-3.28) and 25 incident cases were identified at the follow-up visit for an ... Read More »
» Published in Acta Psychiatr Scand. 2007 Jan;115(1):73-9.

19. Mortality with dementia: results from a French prospective community-based cohort.
Match Strength: 8.766

Despite the magnitude of the problem, little is known about the duration of dementia. Survival and risk factors of mortality with dementia and the impact of dementia on the risk of death were investigated using the Personnes Agees Quid (PAQUID) prospective population-based cohort study between 1988 and 1998. Statistical models dealing with interval censoring were performed. Among 3,675 participants aged 65 years or older and initially nondemented, 2,923 have been followed up for 8 years. Of these, 281 persons with incident dementia were actively diagnosed. The mean age of onset of dementia was ... Read More »
» Published in Am J Epidemiol. 2001 Oct 1;154(7):642-8.

20. Clinical diagnosis of dementia, not behavioral and psychologic symptoms, is associated with psychotropic drug use in community-dwelling elders classified as having dementia.
Match Strength: 8.749

Little is known about the prevalence and correlates of psychotropic drug use in community-dwelling elders with dementia. Baseline data from 285 community-dwelling elders with a research classification of dementia enrolled in the observational Memory and Medical Care Study were analyzed. Of these, 33.3% with a research classification of dementia were clinically diagnosed, 28.8% used at least 1 psychotropic drug, and 61.8% had at least 1 behavioral or psychologic symptom of dementia. Presence of a behavioral or psychologic symptom of dementia was associated with a higher likelihood of a clinical ... Read More »
» Published in J Geriatr Psychiatry Neurol. 2007 Jun;20(2):100-6.

21. Risk factors for dementia in central Nigeria.
Match Strength: 8.737

Little is known about the prevalence of dementia and its associated risk factors in developing countries. Some studies suggest that the prevalence of dementia is lower in developing countries than it is in high-income nations. We sought to determine risk factors for dementia in elderly persons in central Nigeria. Using the standardized Community Screening Instrument for Dementia, we screened a stratified, random community sample of 280 persons aged 65 years and older for dementia. We examined the independent association of known risk factors with dementia using logistic regression. The overall ... Read More »
» Published in Aging Ment Health. 2006 Nov;10(6):616-20.

22. Rural and urban canadians with dementia: use of health care services.
Match Strength: 8.722

The purpose of this research was to examine the characteristics of older Canadians with dementia (compared to those without dementia), their use of health care services, and the impact of place (rural/urban) on use of services. Andersen and Newman's Behavioural Model of Health Services Use (1973) guided the study. A cross-sectional design used data from the Canadian Community Health Survey (CCHS) Cycle 1.1 (N(1/4)49,995 older Canadians; those with dementia(1/4)313). Results indicated that among Canadian females between the ages of 50 and 64, those with dementia were more likely than those ... Read More »
» Published in Can J Aging. 2006 Fall;25(3):321-30.

23. Maladaptive behaviors related to dementia status in adults with down syndrome.
Match Strength: 8.705

Changes in maladaptive behaviors related to specific stages of dementia were investigated in 251 adults 45 years of age and older with Down syndrome. Findings indicate clear differences in maladaptive behaviors at various stages of dementia. Generally, individuals with no signs or symptoms of dementia displayed fewer and less severe maladaptive behaviors than individuals in the early and mid-stages of dementia. Individuals transitioning into the early stages of dementia from no dementia displayed increased aggression, fearfulness, sadness, sleep problems, social inadequacy, stealing, and ... Read More »
» Published in Am J Ment Retard. 2008 Mar;113(2):73-86.

24. Recognition of dementia in hospitalized older adults.
Match Strength: 8.680

Many hospital patients with dementia have no documented dementia diagnosis. In some cases, this is because they have never been diagnosed. Recognition of Dementia in Hospitalized Older Adults proposes several approaches that hospital nurses can use to increase recognition of dementia. This article describes the Try This approaches, how to implement them, and how to incorporate them into a hospital's current admission procedures. For a free online video demonstrating the use of these approaches, go to http://links.lww.com/A216 ... Read More »
» Published in Am J Nurs. 2008 Jan;108(1):40-9; quiz, 50.

25. Vascular dementia: emerging trends.
Match Strength: 8.631

VASCULAR DEMENTIA is a term used to describe a constellation of cognitive and functional impairment that can be viewed as a subset of the larger syndrome of vascular cognitive impairment associated with cerebrovascular brain injury. Vascular dementia is a common disorder among the elderly, although it can also occur in younger persons. Comprising 20% of all cases of dementia in the United States, vascular dementia is the second most common form of dementia after Alzheimer's disease. Patients with vascular dementia often exhibit mood and behavioral changes and may have focal neurological signs ... Read More »
» Published in Semin Neurol. 2007 Feb;27(1):66-77.

26. Differences in risk factors for dementia with neurodegenerative traits and for vascular dementia.
Match Strength: 8.609

In 229 patients with dementia and in 144 control subjects, polymorphisms of apolipoprotein E (ApoE), low-density-lipoprotein (LDL)-receptor-related protein, alpha(2)-macroglobulin, interleukin (IL) 1beta, angiotensin-converting enzyme and of methylene tetrahydrofolate reductase genes were investigated. In plasma, antibodies against Chlamydia pneumoniae and lipids were determined. Dementia was classified as probable Alzheimer's disease (AD), probable dementia of vascular origin (VaD) and mixed dementia (MD). An association of the disease with ApoE and IL-1beta polymorphism and increased levels ... Read More »
» Published in Dement Geriatr Cogn Disord. 2006;22(1):1-7. Epub 2006 Apr 25.

27. Subtypes of depression in dementia.
Match Strength: 8.568

Depression is one of the most frequent neuropsychiatric comorbidities of Alzheimer dementia (AD), affecting patents with rates from 0% to 87%. These rates vary because different populations are sampled and different instruments are used. Depressive symptoms tend to occur early, are persistent, becoming increasingly common as dementia progresses. Depression decreases the quality of life of dementia sufferers, may reduce the duration of survival and would therefore appear to be important to treat. Although questions about the interrelationships between depression and dementia have been central ... Read More »
» Published in Arch Gerontol Geriatr. 2007;44 Suppl:23-33.

28. Perceptions of risk and prevention of dementia in the healthy elderly.
Match Strength: 8.545

OBJECTIVES: (1) To determine the attitudes and perceptions of the elderly with regard to dementia. (2) To correlate these beliefs with demographic variables of age, sex, intelligence scores and social class. METHOD: A postal questionnaire survey of a sample of 562 subjects of the Manchester University Age and Cognitive Performance longitudinal study group. RESULTS: The response rate was 95%. Most responders (69%) did not worry about dementia, although they were more likely to think about it if they had a family member with dementia (p < 0.005). There is no link between social class, sex, ... Read More »
» Published in Dement Geriatr Cogn Disord. 2007;23(6):368-71. Epub 2007 Mar 26.

29. Prevalence of major depressive disorder and dementia in psychogeriatric outpatients.
Match Strength: 8.542

The relationship between depression and dementia in the elderly has been widely investigated, but the real interplay between these variables is still not clear. This observational study highlights the influence of some basic variables, such as sex and age, in the development of dementia and major depression. It shows (i) the importance of sex in the age of onset of depression and dementia, (ii) the presence of two types of depressive syndrome, the first linked to the development of dementia, the second as reactive depression; (iii) the need for more attention to depressive symptoms in young ... Read More »
» Published in Arch Gerontol Geriatr. 2007;44 Suppl:101-4.

30. Uncommon causes of dementia: an historical account.
Match Strength: 8.512

The search for the possible causes of common and uncommon forms of dementia has a long and interesting history. This paper presents a brief review of how the concept of dementia has evolved over time and an historical outline of the causative factors associated with these disorders. Currently available evidence leads to the conclusion that there is only one common cause of dementia: Alzheimer's disease with or without other overlapping pathological processes (such as cerebrovascular disease, traumatic brain injury, etc.). All other forms of dementia are, in isolation, uncommon. Publication ... Read More »
» Published in Int Psychogeriatr. 2005;17 Suppl 1:S3-15.

31. Prevalence of dementia according to DSM-III-R and ICD-10: results of the Leipzig Longitudinal Study of the Aged (LEILA75+) Part 1.
Match Strength: 8.480

BACKGROUND: The prevalence of dementia diagnosis according to ICD-10 and DSM-III-R in population surveys remains poorly understood. AIMS: To report and compare prevalence rates according to DSM-III-R and ICD-10. METHOD: A population-based sample (n=1692, age 75+years) was investigated by a Structured Interview for Diagnosis of Dementia of Alzheimer Type, Multiinfarct Dementia and Dementia of other Aetiology according to DSM-III-R and ICD-10 (SIDAM). RESULTS: Whereas 17.4% (95% CI=15.9-19.5) of individuals aged 75+ years suffer from dementia according to DSM-III-R, only 12.4% (95% CI=10.6-14.2) ... Read More »
» Published in Br J Psychiatry. 2001 Sep;179:250-4.

32. Relationship between anxiety and agitation in dementia.
Match Strength: 8.466

Anxiety and agitation are common in people with dementia. Their consequences can be severe, including increased mortality rates and institutionalization. Despite the importance of these symptoms there is little literature in this area. Some studies have assumed that agitation is the outward manifestation of anxiety, while others have attempted to differentiate between them. The aim of this study was to investigate the relationship between anxiety and agitation in people with mild-to-moderate dementia. A secondary aim was to compare two measures of anxiety which have been used in people with ... Read More »
» Published in Aging Ment Health. 2006 Jul;10(4):362-7.

33. Neuroimaging should not be a routine investigation in all cases of suspected dementia.
Match Strength: 8.447

Dementia is, of course, the label for a clinical syndrome with many different causes. Alzheimer's disease (AD) is the most common cause of dementia, followed by vascular dementia, dementia with Lewy bodies (DLB) and (especially at younger ages) frontotemporal dementia. Other possible causes of the dementia syndrome with relevance to a debate on the use of neuroimaging include space-occupying lesions, normal pressure hydrocephalus and other rarer neurological diseases which can be associated with variable cognitive impairments, such as progressive supranuclear palsy, multi-system atrophy and ... Read More »
» Published in Int Psychogeriatr. 2006 Dec 19;:2-9

34. The role of conventional MR and CT in the work-up of dementia patients.
Match Strength: 8.446

Neuroimaging can play an important role in distinguishing one form of dementia from another. Advanced imaging techniques continue to provide greater insight into the underlying pathologic processes in patients who have dementia. Conventional MRI and CT, however, can contribute useful information when interpreting radiologists are familiar with the patterns of volume loss and signal or density changes that are characteristic of various forms of dementia. Publication Types: ... Read More »
» Published in Neuroimaging Clin N Am. 2005 Nov;15(4):789-802, x. Republished in: Magn Reson Imaging Clin N Am. 2006 May;14(2):169-82.

35. Coagulation and Inflammatory Markers in Alzheimer's and Vascular Dementia
Match Strength: 8.440

Alzheimer's disease is classified as a degenerative dementia while vascular dementia is known to be associated with atherothrombosis and classical vascular risk factors. However, over the last decade, there is increasing evidence of the role of haemostatic factors and inflammatory mechanisms in the pathogenesis of Alzheimer's disease. Serum markers of hypercoagulability and markers of inflammation could lead to thrombosis, accelerated atherogenesis and resulting dementia of both Alzheimer's and vascular dementia. In this case control study, we studied these serum markers of coagulation and ... Read More »
» Published in Int J Clin Pract. 2005 Jan;59(1):52-7.

36. Associations between family history of Parkinson's disease and dementia and risk of dementia in Parkinson's disease: A community-based, longitudinal study.
Match Strength: 8.439

Dementia is common in patients with Parkinson's disease (PDD). The etiology of PDD is still unclear, but exciting advances have been made in discovering pathogenetic components in Parkinson's disease (PD), implicating the role of genetic factors. It is, however, still controversial whether genetic factors also contribute to the development of dementia in PD. Thus, we investigated the association between development of dementia and a positive family history of PD or dementia in a community-based study of PD in Rogaland County, Norway (n = 219). The patients were followed prospectively with ... Read More »
» Published in Mov Disord. 2006 Dec;21(12):2170-4.

37. Effect of Dementia and Treatment of Dementia on Time to Discharge from Assisted Living Facilities: The Maryland Assisted Living Study.
Match Strength: 8.435

OBJECTIVES: To estimate the association between dementia and time to discharge from individual assisted living (AL) facilities and examine, in residents with dementia, factors associated with shorter duration of residence in individual AL facilities. DESIGN: Prospective cohort study. SETTING: Twenty-two AL facilities in central Maryland. PARTICIPANTS: Stratified random sample of 198 AL residents followed for a median of 18 months. MEASUREMENTS: Detailed assessments to diagnose dementia; assess treatment of dementia; and rate clinical; cognitive, functional, and quality-of-life measures. ... Read More »
» Published in J Am Geriatr Soc. 2007 Jul;55(7):1031-1037.

38. Promoting hydration in patients with dementia in healthcare settings.
Match Strength: 8.408

This is the second article in a series of five on dementia. It aims to enhance nurses' understanding of dehydration in patients with dementia. Research shows that dehydration is present in up to one quarter of older patients and patients with dementia are likely to have an even higher risk. Dehydration may be harder to recognise in these patients and strategies to identify and prevent dehydration are outlined. Publication Types: Case Reports, ... Read More »
» Published in Nurs Stand. 2006 Jul 12-18;20(44):49-52.

39. The frontal/subcortical dementias: common dementing illnesses associated with prominent and disturbing behavioral changes.
Match Strength: 8.341

Although the most common cause of dementia is Alzheimer's disease, many other common dementing illnesses in the elderly affect the frontal cortex and associated subcortical structures and present with very different symptoms. In general, these illnesses are not detected with typical bedside screening or with conventional dementia assessment tools, such as the Mini Mental State Exam. These illnesses are associated with prominent and disturbing behavioral changes, as well as difficulties with "higher-order" cognitive functions, such as planning and judgment. Common causes of frontal/subcortical ... Read More »
» Published in Geriatrics. 2006 Aug;61(8):23-7.

40. Dementia in AIDS patients in Oslo; the role of HIV encephalitis and CMV encephalitis.
Match Strength: 8.324

In a well-defined population of adult AIDS patients from Oslo, we studied the correlation between clinical dementia and autopsy results. The study included 91% of all adult AIDS patients from Oslo who died between 1983 and 1996. The autopsy rate was 73% (167/229). Twenty-three percent of patients had definite dementia and 24% possible dementia. In more than half of the patients with definite dementia multinucleated giant cells were present in the brain tissue, suggesting that the dementia was due to HIV encephalitis. Diffuse damage of white matter also showed a significant association with ... Read More »
» Published in Scand J Infect Dis. 2001;33(10):755-8.

41. Vascular dementia: a diagnostic challenge.
Match Strength: 8.314

Although vascular dementia was described over a century ago, it remains a difficult and challenging diagnosis. Several sets of clinical criteria have been published in an effort to establish the presence or absence of vascular dementia in a standardized fashion. Clinical studies have demonstrated that they identify different groups of patients and are thus not interchangeable. Retrospective clinicopathological correlations have shown that most are insufficiently sensitive, although they are generally relatively specific. They accurately exclude pure Alzheimer's disease but may include 9% to 39 ... Read More »
» Published in Int Psychogeriatr. 2003;15 Suppl 1:111-4.

42. Institution Type-Dependent High Prevalence of Dementia in Long-Term Care Units.
Match Strength: 8.304

Background/Aims: It is estimated that there are 90,000 patients with dementia in the 23 million habitants of Taiwan, with a few institutions specialized in dementia care. To assess the need of institutional care for dementia, we investigated the institution prevalence of dementia. Methods: We performed stratified randomized sampling of elder residents from different types of institutions in different regions of Taiwan. A 2-stage survey with screening and clinical confirmation was carried out in 2004. Results: In total, 1,525 residents aged 65 years and over in 60 institutions participated in ... Read More »
» Published in Neuroepidemiology. 2007 Mar 30;28(3):142-149

43. Weight Loss and Metabolic Changes in Dementia
Match Strength: 8.291

Weight loss is common in elderly people with dementia, particularly those with Alzheimer s disease, and feeding difficulties are major issues in their care in the later stages of their disease. This review summarizes data from cross-sectional and longitudinal studies of weight changes with dementia, physiologic aspects of the metabolic and nutritional changes in dementia, and treatment strategies to minimize weight loss ... Read More »
» Published in J Nutr Health Aging. 2002 May;6(3):201-5.

44. A vascular risk factor index in relation to mortality and incident dementia.
Match Strength: 8.279

To develop a method for quantifying risks of death and dementia in relation to vascular risk factors the Gothenburg H-70 1901-02 birth cohort was studied (n=380, was followed over 20 years, with 103 incident dementia cases). Separate vascular risk factor indices were calculated using 23 vascular risk factors to predict: (i) dementia-free-survival, and (ii) incident dementia derived from post hoc optimal separation of affected and unaffected cases. Classification of adverse outcomes (dementia/non-dementia; alive/dead) was assessed using receiver-operator characteristic (ROC) curves, and the ... Read More »
» Published in Eur J Neurol. 2006 May;13(5):514-21.

45. Dementia with Lewy bodies: an emerging disease.
Match Strength: 8.275

Dementia with Lewy bodies appears to be the second most common form of dementia, accounting for about one in five cases. The condition is characterized by dementia accompanied by delirium, visual hallucinations, and parkinsonism. Other common symptoms include syncope, falls, sleep disorders, and depression. The presence of both Lewy bodies and amyloidplaques with deficiencies in both acetylcholine and dopamine neurotransmitters suggests that dementia with Lewy bodies represents the middle of a disease spectrum ranging from Alzheimer's disease to Parkinson's disease. The diagnosis of dementia ... Read More »
» Published in Am Fam Physician. 2006 Apr 1;73(7):1223-9. Summary for patients in: Am Fam Physician. 2006 Apr 1;73(7):1230.

46. Montessori-based dementia care.
Match Strength: 8.273

Montessori-based Dementia Care is an approach used in Alzheimer's care that does not involve chemical or physical restraints. This program works by giving the elder with Alzheimer/Dementia a purpose by getting them involved. When staff/families care for a confused Alzheimer/Dementia patient, who is having behaviors, the Montessori program teaches them to look at what is causing the behavior. When assessing the elder to determine what is causing the behavior, the goal is to find the answer, but the answer cannot be dementia. The goal of the program is to bring meaning to the life of an ... Read More »
» Published in Kans Nurse. 2006 Oct;81(9):14.

47. The use of Dementia Care Mapping in people with a learning disability and dementia.
Match Strength: 8.243

Dementia Care Mapping is a method for evaluating quality of life in and quality of care of people with dementia and has been used widely in services for older adults. This article presents a report of Dementia Care Mapping for eight adults with learning disabilities and dementia. Trained ;mappers' observed individuals over a set period and recorded their behaviour every 5 minutes. The person was then assigned a wellbeing or illbeing value for each 5 minute period, based on the mapper's empathic judgement as to how the individual was feeling at that time. Any examples of particularly positive ... Read More »
» Published in J Intellect Disabil. 2007 Jun;11(2):157-65.

48. Differentiating dementias in long-term care patients.
Match Strength: 8.235

Many long-term care residents are diagnosed with dementia, but dementia appears in many forms. Alzheimer's disease, the most common, is typified by a slow onset and relentless progression to complete incapacitation. Vascular dementia usually appears somewhat abruptly, is associated with vascular comorbidities, and has an unpredictable progression pattern. Lewy body dementia shares features of both Alzheimer's and Parkinson's disease; its hallmarks include fluctuating cognitive performance, visual hallucinations, and extrapyramidal motor symptoms. Frontotemporal dementias are associated less ... Read More »
» Published in Consult Pharm. 2007 Jan;22(1):14-6, 18, 21-8.

49. Patterns of and reasons for relocation in dementia care.
Match Strength: 8.229

Because dementia is a progressive disease, the need for care in municipal shelter accommodations might change over time, raising the crucial question whether to relocate an individual. The aim of the study was to investigate the number of relocations between municipal dementia housing units and to examine the patterns and reasons for relocation, together with the various municipal prerequisites for carrying out relocation. Thirty-three managers of 101 dementia care units in 12 municipalities in Sweden were interviewed, and records of persons who had moved into or out of the dementia care units ... Read More »
» Published in Geriatr Nurs. 2007 May-Jun;28(3):193-200.

50. Family work with people with dementia.
Match Strength: 8.220

Family interventions (FI) are used where there is a psychotic illness. This article argues for their use in dementia cases. It looks at the example of a family where the father had recently received a diagnosis of Lewy bodies with dementia. The focus is on the process of working with the patient and his close relatives using an adapted FI model ... Read More »
» Published in Nurs Older People. 2006 Aug;18(7):28-31.

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