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Peer Reviewed Scientific Research Reports.
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1. Benign pediatric localization-related epilepsies. Part I. Syndromes in infancy.
Match Strength: 5.696
There is currently increasing interest in identifying and classifying pediatric benign epilepsy syndromes and recently several new syndromes have been recognized. Benign epilepsy syndromes, by definition, occur in children with normal developmental history, respond well to therapy, and remit without sequelae. The large majority of children with benign epilepsy syndromes follow a truly benign course. The concept of benign epilepsy syndromes has, however, been challenged by the minority of patients who continue to have seizures despite therapy, develop new seizures after initial remission, or ... Read More »
» Published in Epileptic Disord. 2006 Sep;8(3):169-83.
2. Propionic acid induces convulsions and protein carbonylation in rats.
Match Strength: 4.109
Propionic acid (PA) accumulates in patients with propionic acidemia, an inherited metabolic disorder caused by the deficiency of propionyl-CoA carboxylase activity that is clinically characterized by neurological dysfunction, including seizures. However, it is not known whether PA causes seizures in experimental animals. In the current study, we investigated whether intrastriatal injection of PA (0.6-6 micromol) causes seizures and alters protein carbonyl content in the striatum of adult rats. The injection of PA caused the appearance of seizures and increased protein carbonyl content in ... Read More »
» Published in Neurosci Lett. 2006 Nov 13;408(2):151-4. Epub 2006 Sep 25.
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