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1. Endoscopic management of orbital abscesses.
Match Strength: 4.228

Orbital complications of sinusitis have declined in the postantibiotic era. Nonetheless, the development of a subperiosteal or intraorbital abscess remains a serious condition that is best managed through a multidisciplinary approach. Surgical management is almost always indicated when orbital collections are present, and medical therapy plays a complimentary role. The endoscopic approach of draining a medial orbital collection offers significant advantages over the traditional external approach. The preoperative and intraoperative use of computer-aided technology may be a useful adjunct in ... Read More »
» Published in Otolaryngol Clin North Am. 2006 Oct;39(5):1037-47, viii.

2. Effects of a monoclonal anti-alphavbeta3 integrin antibody on blood vessels - a pharmacodynamic study.
Match Strength: 4.156

PURPOSE: The integrin alphavbeta3 is an adhesion molecule expressed by proliferating endothelial cells and antibodies blocking this integrin inhibit angiogenesis in preclinical models. MEDI-522 is a second generation humanized anti-alphavbeta3 antibody designed for antiangiogenic therapy. The purpose of this study was to examine potential effects of this agent on blood vessels. EXPERIMENTAL DESIGN: In a phase I dose escalation study, MEDI-522 was administered by weekly infusions to 25 adult patients with advanced solid organ malignancies. As a surrogate angiogenesis assay, a wound was created ... Read More »
» Published in Invest New Drugs. 2007 Feb;25(1):49-55. Epub 2006 Sep 26.

3. Effect of weight loss on P wave dispersion in obese subjects.
Match Strength: 2.918

OBJECTIVE: The aim of this study was to investigate effect of loss weight on P wave dispersion in obese subjects. RESEARCH METHODS AND PROCEDURES: After a 12-week weight loss program (diet and medical therapy), a total of 30 (24 women and six men) obese subjects who had lost at least 10% of their original weight were included in the present study. All subjects underwent a routine standard 12-lead surface electrocardiogram. Electrocardiograms were transferred to a personal computer by a scanner and then magnified 400 times by Adobe Photoshop software (Adobe Systems, Mountain View, CA). P wave ... Read More »
» Published in Obesity (Silver Spring). 2006 Aug;14(8):1378-82.

4. Localization: conventional and CT simulation.
Match Strength: 2.295

Recent developments in imaging and computer power have led to the ability to acquire large three dimensional data sets for target localization and complex treatment planning for radiation therapy. Conventional simulation implies the use of a machine capable of the same mechanical movements as treatment units. Images obtained from these machines are essentially two dimensional with the facility to acquire a limited number of axial slices to provide patient contours and tissue density information. The recent implementation of cone beam imaging on simulators has transformed them into three ... Read More »
» Published in Br J Radiol. 2006 Sep;79 Spec No 1:S36-49.

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