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Peer Reviewed Scientific Research Reports.
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1. Dopamine agonist therapy in low-response children following traumatic brain injury.
Match Strength: 6.362
The objective of this study was to determine whether a dopamine agonist could improve mental status among children in a low-response state following traumatic brain injury. In an 8-week, prospective, double-blind, randomized trial, 10 children and adolescents ages 8 to 21 years (X = 16.7 years) with traumatic brain injury sustained at least 1 month previously and remaining in a low-response state (Rancho Los Amigos Scale level pound 3) received pramipexole or amantadine. Medication dosage was increased over 4 weeks, weaned over 2 weeks, and then discontinued. At baseline and weekly during the ... Read More »
» Published in J Child Neurol. 2006 Oct;21(10):879-85.
2. Higher order ocular aberrations in eyes with myopia in a Chinese population.
Match Strength: 5.129
PURPOSE: To describe the characteristics of higher order ocular aberrations of adult Chinese eyes with myopia. METHODS: Higher order aberrations in consecutive right eyes of 166 Chinese patients with myopia who enrolled for preoperative assessment for LASIK were retrospectively reviewed. Wavefront aberrations were measured with the Bausch & Lomb Zywave over a 6-mm dilated pupil. The correlations between higher order aberrations and myopia, astigmatism, and age, respectively, were analyzed. RESULTS: Mean patient age was 32.1 +/- 6.2 years, the mean refractive error was sphere -5.23 +/- 1.79 ... Read More »
» Published in J Refract Surg. 2006 Sep;22(7):695-702.
3. Relative contribution of central and peripheral aberrations to overall high order corneal wavefront aberration.
Match Strength: 4.373
PURPOSE: To analyze the influence of specific combinations of corneal high order aberrations on the optical image quality of the cornea before and after photorefractive keratectomy (PRK) for low to high myopia and myopic astigmatism. METHODS: Corneal topography was obtained for 80 eyes that underwent PRK using a scanning-spot excimer laser. The eyes were subdivided into three groups according to the preoperative refraction. The topographical data were imported into a custom software program that combined the Zernike high order terms having the same sign and angular frequency up to seventh ... Read More »
» Published in J Refract Surg. 2006 Sep;22(7):656-64.
4. Plasma oxidants and antioxidants in acute ischaemic stroke.
Match Strength: 2.946
Plasma levels of the oxidants xanthine oxidase, nitric oxide and malondialdehyde and the antioxidants superoxide dismutase, glutathione peroxidase and glutathione reductase, together with total superoxide scavenger activity and non-enzymatic superoxide scavenger activity, were determined in 19 patients with acute ischaemic stroke and 20 controls. Compared with controls, superoxide dismutase, total superoxide scavenger activity, glutathione peroxidase and glutathione reductase activities were significantly lower, and nitric oxide and malondialdehyde levels significantly higher, in acute stroke ... Read More »
» Published in J Int Med Res. 2006 Jul-Aug;34(4):413-8.
5. Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia.
Match Strength: 2.934
The Plasmodium falciparum variant erythrocyte surface antigens known as PfEMP1, encoded by the var gene family, are thought to play a crucial role in malaria pathogenesis because they mediate adhesion to host cells and immuno-modulation. Var genes have been divided into three major groups (A, B and C) and two intermediate groups (B/A and B/C) on the basis of their genomic location and upstream sequence. We analysed expressed sequence tags of the var gene DBLalpha domain to investigate var gene transcription in relation to disease severity in Malian children. We found that P. falciparum ... Read More »
» Published in Mol Biochem Parasitol. 2006 Dec;150(2):211-8. Epub 2006 Sep 5.
6. Emergency Department Sonographic Measurement of Optic Nerve Sheath Diameter to Detect Findings of Increased Intracranial Pressure in Adult Head Injury Patients.
Match Strength: 2.737
STUDY OBJECTIVE: Our objective is to determine whether a bedside ultrasonographic measurement of optic nerve sheath diameter can accurately predict the computed tomographic (CT) findings of elevated intracranial pressure in adult head injury patients in the emergency department (ED). METHODS: We conducted a prospective, blinded observational study on adult ED patients with suspected intracranial injury with possible elevated intracranial pressure. Exclusion criteria were age younger than 18 years or obvious ocular trauma. Using a 7.5-MHz ultrasonographic probe on the closed eyelids, a single ... Read More »
» Published in Ann Emerg Med. 2006 Sep 22;
7. Optical quality of the cornea after overnight orthokeratology.
Match Strength: 2.583
PURPOSE:: To review changes in the optical quality of the cornea induced by overnight orthokeratology for myopia. METHODS:: Sixty-four eyes of 39 patients who underwent overnight orthokeratology for myopia were prospectively examined. Inclusion criteria were uncorrected visual acuity of 20/20 or better after treatment and a minimum follow-up of 3 months. To quantitatively assess changes in corneal regular and irregular astigmatism, videokeratography data were decomposed into spherical component, regular astigmatism, asymmetry, and higher-order irregularity using Fourier analysis. In addition, ... Read More »
» Published in Cornea. 2006 Dec;25 Suppl 1:S59-63.
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