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Brain Abscess
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1. Brain abscess observed by localized proton magnetic resonance spectroscopy.
Match Strength: 13.720

We encountered a case of brain abscess that was difficult to differentiate from glioblastoma. Localized 1H-MRS was found to be useful for obtaining information on the biochemical status of brain abscess. The peak of lipid and high residual peak of NAA (N-acetyl-aspartate) were observed in the cystic lesion of the brain abscess by 1H-MRS. The NAA/Cho (Choline-containing compounds) ratio in brain parenchyma showing an edematous lesion before therapy gradually increased with the relief of inflammation ... Read More »
» Published in Magn Reson Imaging. 1994;12(8):1269-74.

2. Brain abscess secondary to frontal osteomyelitis.
Match Strength: 13.180

Frontal osteomyelitis is a rare complication of sinusitis. Common intracranial complications of the frontal osteomyelitis are meningitis, epidural empyema, subdural empyema and brain abscess. We described a case of frontal osteomyelitis with brain abscess caused by Staphylococcus aureus with improve after needle aspiration and antibiotics to brain abscess for eight weeks and for chronic osteomyelitis for four months. Publication Types: Case ... Read More »
» Published in Rev Inst Med Trop Sao Paulo. 2006 Jul-Aug;48(4):233-5.

3. Percutaneous PFO closure for the prevention of recurrent brain abscess.
Match Strength: 12.689

A patent foramen ovale (PFO) can act as a conduit between the venous and arterial circulations, allowing right-to-left shunting and bypass of the pulmonary circulation. Brain abscess may develop as a result of paradoxical embolism of organisms through a PFO. In this small series, we report on the closure of PFO for the prevention of recurrent brain abscess. Only prospective, randomized trials comparing PFO closure to conservative therapy could provide a definitive answer as to the optimal strategy for preventing recurrent cerebral abscess ... Read More »
» Published in Catheter Cardiovasc Interv. 2006 Dec;68(6):957-60.

4. Penetration and Activity of Antibiotics in Brain Abscess
Match Strength: 12.659

Penetration of antimicrobial agents into the cerebrospinal fluid is dependent on numerous factors, including their serum protein binding, molecular size and lipid solubility, and degree of local inflammation. The choice of an appropriate agent is further complicated by diverse bacterial flora involved in brain abscess, local resistant patterns and activity of the drug in abscess environment. This update examines the conventional and newer agents in the above context for their role in the management of brain abscess ... Read More »
» Published in J Coll Physicians Surg Pak. 2005 Mar;15(3):165-7.

5. Brain abscess following intracerebral haemorrhage.
Match Strength: 12.535

We report two cases of brain abscess, which developed at the site of an intracerebral haemorrhage (ICH) in a 75-year-old man and a 32-year-old-man. The patients recovered after surgical treatment and systemic antibiotic therapy. The route of infection could not be detected in either case. The literature contains only 13 reported cases of brain abscess as a complication of ICH. Although the interval from initial ICH to abscess formation ranged from 4 to 20 weeks, almost all patients had episodes of high fever, indicating the presence of systemic infection and bacterial seeding, 0-14 days after ... Read More »
» Published in J Clin Neurosci. 2006 Dec;13(10):1047-51.

6. Brain abscess in a dog immunosuppressed using cyclosporin.
Match Strength: 12.409

This report describes a dog that developed brain abscesses following prolonged immunosuppression with cyclosporin. Bacteria within the abscess were most likely Nocardia, an organism well recognised in immunosuppressed humans, and probably reached the brain through haematogenous spread from a more long-standing abscess in the mediastinum. Bacterial brain abscesses developing in this manner are very rare in dogs and this case highlights the wider range of possible diagnoses that need to be considered in immunosuppressed patients and the care with which potent drugs such as cyclosporin should be ... Read More »
» Published in Vet J. 2006 May 9;

7. Brain abscess following dental procedures. Case report.
Match Strength: 12.366

There have been a number of reports of brain abscess suggesting an odontogenic etiology after dental treatment procedures or oral infections, but the diagnosis was mainly by exclusion rather than based on evidence. We present a case of a brain abscess due to Strepto-coccus constellatus in a 27-year-old-immunocompetent woman who underwent extraction of the primary molar and eradication of a radicular cyst some weeks before ... Read More »
» Published in Minerva Stomatol. 2007 May;56(5):303-5.

8. Hemorrhage Into the Brain Abscess Cavity With Fallot's Tetralogy
Match Strength: 12.353

Hemorrhage into the abscess cavity is a complication of brain abscess. It has been reported to be due to inflammation which results in the damage of the fragile neovasculature of the abscess wall. Hypoxia caused by Fallot's tetralogy or other congenital heart diseases facilitates the damage of these vessels with the lacking supportive tissues, and in turn intracavital bleeding. Copyright 2006 S. Karger AG, ... Read More »
» Published in Pediatr Neurosurg. 2006;42(1):65-6.

9. Trans-mastoid approach to otogenic brain abscess.
Match Strength: 12.303

The treatment of otogenic brain abscess initially involves excision or aspiration of the abscess through a temporal or sub-occipital route depending on its location. This is followed by a mastoidectomy by the ENT surgeon to eradicate the primary source of infection. During the last three years, we have approached such lesions through a mastoidectomy followed by excision of the abscess through the same approach. This trans-mastoid approach is technically feasible in following the tract of suppuration, and clearing the cause and effect of pathology, at the same sitting. This paper describes our ... Read More »
» Published in J Pak Med Assoc. 2006 Mar;56(3):132-5.

10. Molecular identification of Leuconostoc mesenteroides as a cause of brain abscess in an immunocompromised patient.
Match Strength: 11.917

Leuconostoc species are emerging pathogens that can cause severe infections, particularly in immunocompromised patients. Using molecular methods, we identified Leuconostoc mesenteroides as the cause of a brain abscess which was successfully treated by surgery and antimicrobial treatment. This is the first report of brain abscess caused by this species. Publication Types: Case Reports, Research Support, Non-U.S. Gov ... Read More »
» Published in J Clin Microbiol. 2006 Aug;44(8):3044-5.

11. Nocardia farcinica brain abscess in a patient without immunocompromise.
Match Strength: 11.841

Brain abscess has an incidence of 1 per 100,000 in developed countries and a mortality rate of 10%. Cerebral infections with Nocardia farcinica have a mortality of up to 90%. Nocardial species are important pathogens in immunocompromised hosts, but infections in immunocompetent patients are extremely rare. We report a case of primary brain abscess with N. farcinica in a patient without immunosuppression, which was treated with surgery and a one-year course of oral moxifloxacin ... Read More »
» Published in Br J Neurosurg. 2007 Jun;21(3):301-3.

12. Persistent Immune Activation Associated With a Mouse Model of Staphylococcus Aureus-Induced Experimental Brain Abscess
Match Strength: 11.635

We have established a mouse experimental brain abscess model using Staphylococcus aureus where lesion sites are greatly exaggerated compared to the localized area of initial infection, reminiscent of an overactive immune response. Here we demonstrate the prolonged expression of IL-1 beta, TNF-alpha, and macrophage inflammatory protein-2 (MIP-2/CXCL2), concomitant with a chronic disruption of the blood-brain barrier (BBB) in mice with S. aureus-induced brain abscess. These changes correlated with the continued presence of infiltrating neutrophils and macrophages/microglia. Collectively these ... Read More »
» Published in J Neuroimmunol. 2004 Jun;151(1-2):24-32.

13. Aquaporin-4 gene deletion in mice increases focal edema associated with staphylococcal brain abscess.
Match Strength: 11.622

Brain abscess is associated with local vasogenic edema, which leads to increased intracranial pressure and significant morbidity. Aquaporin-4 (AQP4) is a water channel expressed in astroglia at the blood-brain and brain-CSF barriers. To investigate the role of AQP4 in brain abscess-associated edema, live Staphylococcus aureus (10(5) colony-forming units) was injected into the striatum to create a focal abscess. Wild-type and AQP4-deficient mice had comparable immune responses as measured by brain abscess volume (approximately 3.7 mm3 at 3 days), bacterial count and cytokine levels in brain ... Read More »
» Published in J Neurochem. 2005 Oct;95(1):254-62.

14. In vivo demonstration of neuroinflammatory molecule expression in brain abscess with diffusion tensor imaging.
Match Strength: 11.503

BACKGROUND AND PURPOSE: Neuroinflammatory molecules, including tumor necrosis factor-alpha, interleukin1-beta, lymphocyte function associated molecule-1, and intercellular cell adhesion molecule-1 contribute to the development of brain abscess. We hypothesized that the high fractional anisotropy (FA) in the brain abscess cavity reflects the upregulation of these neuroinflammatory molecules. Materials and METHODS: Diffusion tensor imaging (DTI) was performed in 24 patients with brain abscess and Staphylococcus aureus-treated as well as nontreated Jurket cell lines (at 4 time points: 1, 24, 48, ... Read More »
» Published in AJNR Am J Neuroradiol. 2008 Feb;29(2):326-32. Epub 2007 Nov 7.

15. Brain abscess in adult cirrhotic patients: two case reports.
Match Strength: 11.473

Patients who have liver cirrhosis are at increased risk of bacterial infections, such as bacteremia, meningitis, pneumonia, urinary tract infections, and spontaneous bacterial peritonitis, due to immunodeficiency associated with the severity of the cirrhosis. Although bacterial infections are frequent in cirrhotic patients, only isolated cases of brain abscess have been reported. In these cirrhotic patients, the initial presentation of brain abscess may not be fever or leukocytosis, but focal neurologic deficits. In addition, for consideration of blood-brain barrier penetration, the anti ... Read More »
» Published in Kaohsiung J Med Sci. 2007 Jan;23(1):34-9.

16. Brain abscess: clinical aspects of 100 patients.
Match Strength: 11.421

OBJECTIVE: To verify if, in the last two decades, there have been any changes in epidemiological, clinical, diagnostic, therapeutic and prognostic aspects of patients with brain abscess. METHOD: We studied retrospectively 100 patients discharged over a 17-year period from Ca' Foncello Regional Hospital, Treviso, Italy with a diagnosis of brain abscess. RESULTS: Post-surgical abscesses were more frequent than those related to contiguous infections and the spectrum of etiologic agents was very heterogeneous. A cerebral neoplasm was the initial neuroradiological diagnosis in 13 patients; 72 ... Read More »
» Published in Int J Infect Dis. 2006 Mar;10(2):103-9. Epub 2005 Nov 28.

17. Neisseria elongata endocarditis complicated by brain embolism and abscess.
Match Strength: 11.407

We report a case of Neisseria elongata endocarditis with thalamic septic embolization and subsequent brain abscess formation, which to the best of our knowledge has never been reported in the literature. The brain abscess completely resolved after a surgical repair of the infected mitral valve and an additional 4 weeks of antimicrobial therapy. Based on a review of all previous reports of N. elongata endocarditis, including ours, this will remind physicians that invasive N. elongata infections should be managed and followed up cautiously, as surgical intervention is often required ... Read More »
» Published in J Med Microbiol. 2008 Mar;57(Pt 3):376-81.

18. Otogenic brain abscess: management by otologist.
Match Strength: 11.345

INTRODUCTION: Fifty per cent of brain abscesses in adults and 25 per cent of those in children are otogenic in origin. The current neurosurgical options are to drain the abscess repeatedly through burr holes or to excise it completely with the capsule. We successfully managed 10 cases of brain abscess by draining through the transmastoid route. The technique and its advantages are discussed. MATERIAL AND METHODS: The patients underwent surgery at two different institutions. Computed tomography scanning and magnetic resonance imaging were performed, along with diffusion-weighted imaging and in ... Read More »
» Published in J Laryngol Otol. 2006 Oct;120(10):837-41. Epub 2006 Jul 6.

19. Comparison of the magnetization transfer ratio and fluid-attenuated inversion recovery imaging signal intensity in differentiation of various cystic intracranial mass lesions and its correlation with biological parameters.
Match Strength: 11.248

PURPOSE: To compare the signal intensity on the fluid attenuated inversion recovery (FLAIR) sequence and magnetization transfer ratios (MTRs) for the differentiation of abscesses from non-abscess cystic brain lesions, and to correlate these MR parameters with the viscosity, viable cell density and total protein concentration of the cystic fluid. MATERIALS AND METHODS: Signal intensity on FLAIR and MTRs from the cystic cavity of lesions were calculated from 33 patients (brain abscess (N = 12) and non-abscess (N = 21)). The fluid from the lesion was aspirated at the time of surgery, and the ... Read More »
» Published in J Magn Reson Imaging. 2006 Jul;24(1):52-6.

20. Cerebrovascular permeability and delivery of gentamicin to normal brain and experimental brain abscess in rats.
Match Strength: 11.111

Antibiotics vary widely in their ability to penetrate the blood-brain barrier. In studies of 70 rats, the permeability of the normal blood-brain barrier to gentamicin was shown to be poor. In experimental brain abscesses, during the cerebritic stage of development, the penetration of intravenous antibiotics was increased compared to normal brain but was very inconsistent. Antibiotic delivery to brain abscess was not significantly altered with the administration of high-dose steroids, but the macrophage and glial response was markedly decreased with high-dose steroid therapy. Reversible osmotic ... Read More »
» Published in J Neurosurg. 1984 Sep;61(3):430-9.

21. Brain abscess due to Listeria monocytogenes: first case report in Thailand.
Match Strength: 10.995

Brain abscess with bacteremia caused by Listeria monocytogenes in a young woman with immune thrombocytopenic purpura was reported. The clinical features included fever, headache, and left-side weakness. Computed tomography and magnetic resonance imaging of the brain showed a large single abscess at the right frontoparietal area. L. monocytogenes was isolated from a blood culture. The patient promptly received a surgical drainage. Because she had a history of penicillin allergy, and the organism was resistant to ampicillin, she was treated with trimethoprim-sulfamethoxazole (TMP-SMX) alone for ... Read More »
» Published in J Med Assoc Thai. 2006 Sep;89(9):1516-20.

22. Vegetation on patent foramen ovale presenting as a cryptogenic brain abscess.
Match Strength: 10.981

This paper describes a case of 51-year-old man with a vegetation on his patent foramen ovale presenting with a cryptogenic brain abscess. He received surgical evacuation and was successfully managed with septal occlusion. This is the first reported case of cryptogenic brain abscess caused by a vegetation on a patent foramen ovale directly documented with transesophageal echocardiography ... Read More »
» Published in Int J Cardiol. 2007 Mar 12;

23. Retrospective analysis of 49 cases of brain abscess and review of the literature.
Match Strength: 10.974

The case records of 49 patients discharged from St George's Hospital, London, between December 2000 and March 2004 with the diagnosis of brain abscess were reviewed in order to document the epidemiology, causes, treatment, and prognostic factors associated with brain abscess. Brain abscess occurred at all ages, more frequently in men than in women. Headache and altered mental status were common presenting symptoms. The frontal lobe was the most common site. Streptococcal infection was seen most commonly, but staphylococcal infection predominated in cases following neurosurgery. Computed ... Read More »
» Published in Eur J Clin Microbiol Infect Dis. 2006 Dec 19;

24. A case of isolated Nocardia asteroides brain abscess in a kidney transplant recipient.
Match Strength: 10.940

Because of the immunosuppressive drugs used after organ transplantation, there is an increased rate of certain infections and malignancies. Nocardia brain abscess is a rare condition, seen most commonly among immunocompromised patients. It may be confused with intracranial tumors and requires long-term combined antibiotic therapy after drainage. CASE REPORT: A patient who underwent renal transplantation because of end-stage renal disease of unknown origin was shown to have a nocardial brain abscess while she was taking immunosuppressive drugs. The patient was given combined antibiotics and the ... Read More »
» Published in Transplant Proc. 2006 Nov;38(9):3121-4.

25. Echinococcosis presenting as an otogenic brain abscess: an unusual lesion of the middle ear cleft and temporal lobe.
Match Strength: 10.929

This paper presents a case of a 28-year-old male with a seizure episode and a 4-year history of intermittent tinnitus on the left ear. On computed tomography and magnetic resonance imaging, a density with rim enhancement was found at the temporal lobe, associated with mastoid tegmen destruction and middle ear mass, indicating cholesteatoma with complicating brain abscess. Evacuation of the brain abscess was performed with a combined otolaryngologic and neurosurgical procedures (canal wall-down mastoidectomy and temporal craniotomy). The pathology turned out to be infestation with Echinococcus ... Read More »
» Published in Auris Nasus Larynx. 2008 Mar;35(1):115-20. Epub 2007 Sep 10.

26. Cerebral abscess associated with meningococcal meningitis.
Match Strength: 10.922

Purulent fluid collections, including brain abscess and subdural empyema, are exceedingly rare in association with meningococcal meningitis. We present a 5-month-old infant with meningococcal meningitis and sepsis complicated by an intracerebral abscess. Publication Types: Case ... Read More »
» Published in Pediatr Infect Dis J. 2006 Aug;25(8):754-6.

27. A rapidly enlarging nocardial brain abscess mimicking malignant glioma.
Match Strength: 10.762

Nocardial brain abscesses are uncommon and are not preceded by clear infectious symptoms in most cases. Delayed identification of the bacteria is responsible for a high mortality rate. A 58-year-old afebrile woman was admitted to our hospital because of progressive right hemiparesis and aphasia. Magnetic resonance imaging (MRI) showed a single ring-enhanced lesion in the left frontal lobe. It was extremely difficult to establish the diagnosis of brain abscess, because the laboratory data provided little evidence of bacterial infection, (201)TlCl-scintigraphy revealed definite accumulation of ... Read More »
» Published in J Nippon Med Sch. 2005 Oct;72(5):308-11.

28. Effect of Dexamethasone on Experimental Brain Abscess
Match Strength: 10.746

Dexamethasone has been used to manage brain edema in patients with intracranial abscess. However, its administration has often been delayed or avoided for fear of adverse effects upon normal host responses to infection. An experimental model of brain abscess in the rat was developed to determine if dexamethasone produced adverse effects on immune competence and collagen deposition in the region of the abscess. Sprague-Dawley rats were inoculated with Staphylococcus aureus and treated intraperitoneally each day with either dexamethasone (0.25 mg/kg) or saline solution. Surviving animals were ... Read More »
» Published in J Neurosurg. 1987 Feb;66(2):264-9.

29. Lung Abscess: Back for an Encore?
Match Strength: 10.706

The rise in incidence of lung abscess due to opportunistic organisms has reemphasized the need for early recognition and treatment. Opportunistic organisms can cause lung abscess in immunocompromised hosts. Most lung abscesses are primary, occurring as a result of aspiration of oral contents into the dependent portions of the lung in persons with dysphagia or decreased consciousness. Symptoms of lung abscess include productive cough, fever, leukocytosis, weight loss, and putrid sputum. Among the complications are progression to a chronic stage, empyema, massive hemoptysis, metastatic brain ... Read More »
» Published in Postgrad Med. 1982 Jul;72(1):215-8.

30. An unusual case of brain abscess by Gemella morbillorum.
Match Strength: 10.689

A case of deep brain abscess by Gemella morbillorum is described. Due to high fever, lethargy, severe headache, and the risk of intraventricular rupture of the suppurative lesion, a CT-guided stereotactic aspiration of the abscess was successfully performed. The patient responded well to a 6-week course of meropenem, metronidazole, and fluconazole. Gemella spp. should not be considered as trivial commensals of the mucous membranes, but appear as emerging pathogens involved in endocarditis, septic shock, and necrotizing pneumonia, as well as in serious intracranial infections. Publication Types ... Read More »
» Published in Jpn J Infect Dis. 2006 Apr;59(2):126-8.

31. Brain abscess caused by Streptococcus pneumoniae with acute onset and rapid progressive symptoms.
Match Strength: 10.567

Although the decline of the morbidity and mortality in recent years, brain abscess is still an important problem in neurocritical care medicine and remains a serious illness that can result in severe disability or even death, especially if misdiagnosed or managed improperly. We report a very rare case of a patient who developed a bacterial brain abscess in the posterior fossa with an atypical rapid progression of neurological symptoms. Furthermore, MRI demonstrated additional brain stem and left hemispheric lesions. Early onset broad antibiotic therapy, corticosteroid application and extensive ... Read More »
» Published in Eur J Med Res. 2007 Apr 26;12(4):181-2.

32. Arterial brain infarction in complicated acute otitis media.
Match Strength: 10.497

We report a rare case of acute otitis media (AOM) complicated by arterial brain infarction, meningitis and orbital cellulitis. Computed tomography (CT) initially showed suspected epidural abscess, coalescent mastoiditis, and orbital cellulitis. Further clinical deterioration occurred following mastoidectomy and evacuation of the abscess. Magnetic resonance imaging (MRI) revealed subacute brain infarction and an extra-axial brainstem abscess. Revision of the initial CT revealed subtle signs suggestive of arterial brain infarction. Although CT with contrast is the standard of care for suspected ... Read More »
» Published in Int J Pediatr Otorhinolaryngol. 2007 Jan 19;

33. The role of diffusion-weighted imaging in the differential diagnosis of intracranial cystic mass lesions: a report of 147 lesions.
Match Strength: 10.364

BACKGROUND: The objective of this study is to evaluate the sensitivity and specificity of DWI in differentiating brain abscesses from other intracranial cystic lesions. METHODS: One hundred fifteen patients with 147 cystic lesions (mean age, 26.4 year) were prospectively studied with DWI on a 1.5-T magnetic resonance imaging. Lesions appearing hyperintense on DWI with the ADC values of lower than 0.9 +/- 0.13 x 10(-3) mm(2)/s (mean +/- SD) were considered as brain abscess, whereas hypointense lesions on DWI with the ADC values 2.2 +/- 0.9 x 10(-3) mm(2)/s were categorized as nonabscess cystic ... Read More »
» Published in Surg Neurol. 2006 Sep;66(3):246-50; discussion 250-1.

34. Brain abscess due to Streptococcus acidominimus: first case report.
Match Strength: 10.359

BACKGROUND: Streptococcus acidominimus resembles Streptococcus viridans, but they can now be differentiated by phenotypic studies. Only a single previous case of pneumonia, pericarditis, and meningitis has been reported. CASE DESCRIPTION: We recently encountered a patient with brain abscess from which S acidominimus was isolated after initially being recorded as S viridans. Because 49% of all S viridans isolated from abscesses are resistant to beta-lactam antimicrobials, speciation is important as well as in vitro sensitivity testing. Streptococcus acidominimus is ordinarily sensitive to beta ... Read More »
» Published in Surg Neurol. 2007 Mar;67(3):296-7.

35. Clinical characteristics of fusobacterial brain abscess.
Match Strength: 10.358

We retrospectively reviewed 122 patients with culture-proven bacterial brain abscesses (BBA) at our hospital over a period of 20 years and identified seven fusobacterial brain abscess patients. Here we describe the therapeutic experience in fusobacterial BBA cases and compare the clinical features of patients with single pathogen infection between fusobacterial and non-fusobacterial brain abscesses. Fusobacterium spp. accounted for 6% of the implicated pathogens of monomicrobial BBA. All seven fusobacterial brain abscess patients contracted the infection spontaneously, and two cases had ... Read More »
» Published in Jpn J Infect Dis. 2007 Feb;60(1):40-4.

36. Lethal brain abscess due to the fungus Scedosporium apiospermum (teleomorph Pseudallescheria boydii) after a near-drowning incident: case report and review of the literature.
Match Strength: 10.346

A 39-year-old healthy man developed a brain abscess weeks after a near-drowning incident. Scedosporium apiospermum, the anamorph of Pseudallescheria boydii, was isolated from the abscess. The patient died 153 days after the accident despite antifungal therapy. We discuss the role of antifungals and review the literature for comparable cases. Publication Types: Case Reports, ... Read More »
» Published in Med Mycol. 2006 Aug;44(5):473-7.

37. Neonatal bacterial meningitis complicated with multiple brain abscesses and intraventricular rupture: report of one case.
Match Strength: 10.310

Brain abscess is rarely encountered in neonates and carries a high morbidity and mortality. Here we report a premature infant who developed systemic Escherichia coli (E. coli) infection resulting in multiple brain abscesses with intraventricular rupture at 3 months postnatal age. He was treated successfully with a combination of surgical and antimicrobial therapies. Related literature on brain abscess with special emphasis on intraventricular rupture is reviewed ... Read More »
» Published in Acta Paediatr Taiwan. 2006 Jul-Aug;47(4):205-9.

38. Clinical features and outcome of 83 adult patients with brain abscess.
Match Strength: 10.252

Brain abscess continues to be a problem in neurosurgery and associates with morbidity and mortality even in the antibiotics and computed tomography (CT) era. In this study, we tried to recognize the indications of operation, effectiveness of preoperative CT scan, and antibiotic therapy in the diagnosis and treatment of these patients, and to identify the morbidity and mortality rates of adult patients with brain abscess. In a retrospective study from 1994 through 2004, we reviewed 83 adult patients with brain abscess (aged>16 years), who had been treated medically or surgically by the ... Read More »
» Published in Arch Iran Med. 2007 Jul;10(3):379-282.

39. Postneurosurgical nosocomial bacterial brain abscess in adults.
Match Strength: 10.240

BACKGROUND: Bacterial brain abscess after a neurosurgical procedure has become an important occurrence in the hospital setting. However, no information about the frequency, clinical relevance, and the outcome has been reported. PATIENTS AND METHODS: Over a period of 19 years (1986- 2004), a total of 31 patients were retrospectively identified as having brain abscesses after neurosurgical procedures and were enrolled in this study. RESULTS: Those included in this study accounted for 0.17% (31/18600) of all neurosurgical procedures in the same period. There was an increased percentage of adult ... Read More »
» Published in Infection. 2006 Oct;34(5):247-51.

40. Proinflammatory cytokine, chemokine, and cellular adhesion molecule expression during the acute phase of experimental brain abscess development
Match Strength: 10.239

Brain abscess represents the infectious disease sequelae associated with the influx of inflammatory cells and activation of resident parenchymal cells in the central nervous system. However, the immune response leading to the establishment of a brain abscess remains poorly defined. In this study, we have characterized cytokine and chemokine expression in an experimental brain abscess model in the rat during the acute stage of abscess development. RNase protection assay revealed the induction of the proinflammatory cytokines interleukin (IL)-1alpha, IL-1beta, IL-6, and tumor necrosis factor ... Read More »
» Published in Am J Pathol. 2000 Aug;157(2):647-58.

41. Evolution of Brain Abscess in Cats Formation of Capsule and Resolution of Brain Edema
Match Strength: 10.192

Brain abscess evolution was studied in an experimental model in the cat correlating the computed tomographic scan appearance with intracranial pressure, brain edema and histopathological findings. Brain inflammation was produced by direct inoculation of Staphylococcus aureus into the white matter. Abscesses developed in all animals. The ring enhancement around the necrotic focus seen at an early stage after contrast-medium injection cannot be equated with capsule formation as long as the abscess diameter increased. Parallel to the acute stage of abscess, the intraventricular pressure increased ... Read More »
» Published in Neurosurg Rev. 1980;3(2):101-11.

42. Biological correlates of diffusivity in brain abscess.
Match Strength: 10.185

Restricted diffusion in brain abscess is assumed to be due to a combination of inflammatory cells, necrotic debris, viscosity, and macromolecules present in the pus. We performed diffusion-weighted imaging (DWI) on 41 patients with proven brain abscesses (36 pyogenic and five tuberculous), and correlated the apparent diffusion coefficient (ADC) from the abscess cavity with viable cell density, viscosity, and extracellular-protein content quantified from the pus. On the basis of the correlation between cell density and ADC in animal tumor models and human tumors in the literature, we assumed ... Read More »
» Published in Magn Reson Med. 2005 Oct;54(4):878-85.

43. Nocardial brain abscess: review of clinical management.
Match Strength: 10.129

Nocardiosis has become a significant opportunistic infection over the last two decades as the number of immunocompromised individuals has grown worldwide. We present two patients with nocardial brain abscess. The first patient was a 39-year-old woman with systemic lupus erythematosus. A left temporoparietal abscess was detected and aspirated through a burr-hole. Nocardia farcinica infection was diagnosed. The patient had an accompanying pulmonary infection and was thus treated with imipenem and amikacine for 3 weeks. She received oral minocycline for 1 year. The second patient was a 43-year ... Read More »
» Published in J Clin Neurosci. 2006 May;13(4):481-5.

44. A case of frontal lobe abscess as a complication of frontal sinus ossifying fibroma.
Match Strength: 10.126

Sinonasal ossifying fibroma is a rare, slow-growing, benign bony tumour, frequently involving the maxilla and mandible in the head and neck region. Although it is known to be the second most frequent fibro-osseous tumour of paranasal sinus, to the best of our knowledge, ossifying fibroma of frontal sinus causing brain abscess has not been presented yet in the relevant literature. We present the clinical, pathological and radiological findings of ossifying fibroma of the frontal sinus associated with brain abscess. Publication Types: Case ... Read More »
» Published in Dentomaxillofac Radiol. 2006 Nov;35(6):447-50.

45. Case Report. Evolution of Cerebral Abscess: Disparity Between Radionuclide and Ct Scans
Match Strength: 10.121

The course of frontal lobe cerebritis in a teenage boy was followed with serial radionuclide and CT scans. During treatment with high doses of dexamethasone and antibiotics, the radionuclide scans became normal, whereas the CT scans remained abnormal and ultimately demonstrated an encapsulated abscess that was successfully drained. In patients receiving steroid therapy, the radionuclide brain scan may not be a reliable technique in demonstrating an intracranial abscess ... Read More »
» Published in Postgrad Med. 1978 May;63(5):226, 229-30.

46. Discrimination of an infected brain tumor from a cerebral abscess by combined MR perfusion and diffusion imaging.
Match Strength: 10.020

The aim of this study was to investigate the signal characteristics of the abscess wall and tumor wall on diffusion-weighted and perfusion-weighted images and thus to evaluate the feasibility of using combined MR diffusion and perfusion imaging to differentiate pyogenic cerebral abscess from infected brain tumor. The tumor wall of various types of cystic or necrotic brain tumor was significantly hyperintense relative to that of cerebral abscess wall on both diffusion-weighted images and regional cerebral blood volume maps.Sixteen patients who had cerebral masses with large cystic or necrotic ... Read More »
» Published in Comput Med Imaging Graph. 2002 Jan-Feb;26(1):19-23.

47. Brucellar brain abscess and bilateral arachnoid cysts, unilaterally complicated by subdural haematoma.
Match Strength: 9.990

Arachnoid cysts are benign developmental cysts that occur along the cerebrospinal axis. Brucellar abscesses in the brain are relatively uncommon, with only a few cases reported in the literature. We report here a patient with a brucellar brain abscess and bilateral arachnoid cysts (one complicated with subdural haemorrhage), who was successfully managed with craniotomy and antibiotics. Publication Types: Case ... Read More »
» Published in J Clin Neurosci. 2006 May;13(4):485-7.

48. Unusual giant cerebral venous varix associated with brain abscess: variant of hereditary hemorrhagic telangiectasia--case report.
Match Strength: 9.869

A 35-year-old man suffered secondary generalized tonic-clonic convulsions due to a large brain abscess. Neuroimaging incidentally revealed another tumor-like lesion. Cerebral angiography confirmed that the lesion was an unusual giant venous varix associated with a high-flow pial arteriovenous fistula (AVF) and showed one more small arteriovenous malformation (AVM). Pulmonary AVF, which can cause brain abscess, was also detected. Surgical ligation of the AVF and removal of the small AVM via individual craniotomies resulted in successful extirpation of the cerebrovascular malformations. Although ... Read More »
» Published in Neurol Med Chir (Tokyo). 2007 Feb;47(2):74-8.

49. Brain abscess due to Entamoeba histolytica.
Match Strength: 9.860

A patient of cerebral amoebiasis due to Entamoeba histolytica with no evidence of disease elsewhere is described. He made a complete recovery after surgical excision of the abscess along with metronidazole therapy. Publication Types: Case ... Read More »
» Published in J Assoc Physicians India. 2004 Mar;52:251-2.

50. Nocardial cerebral abscess associated with mycetoma, pneumonia, and membranoproliferative glomerulonephritis.
Match Strength: 9.845

Nocardial brain abscesses remain a clinical challenge. We successfully treated a patient with nocardial brain abscess, mycetoma, pneumonia, and glomerulonephritis. Nocardial soft tissue involvement, mycetoma, is well known. However, the fact that actinomycetoma can metastasize may not be as well appreciated. The association between nocardiosis and glomerulonephritis should be better clarified ... Read More »
» Published in J Clin Microbiol. 2007 Jun;45(6):2072-4. Epub 2007 Apr 11.

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