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Peer Reviewed Scientific Research Reports.
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1. New agents for the treatment of fungal infections: clinical efficacy and gaps in coverage.
Match Strength: 4.058
The incidence of fungal infections has increased globally, and the introduction of the newer triazoles and echinocandin antifungals is a more-than-welcome and long overdue development. In this report, we review the clinical trials evaluating the therapeutic efficacy of these new antifungal agents and examine possible gaps in coverage. Voriconazole has become the primary treatment for most forms of invasive aspergillosis in a number of centers, posaconazole offers a broad antifungal spectrum, and echinocandins are fungicidal against most Candida species. Moreover, the new agents are active ... Read More »
» Published in Clin Infect Dis. 2006 Oct 15;43(8):1060-8. Epub 2006 Sep 8. Erratum in: Clin Infect Dis. 2006 Nov 1;43(9):1232.
2. Postmortem findings and opportunistic infections in HIV-positive patients from a public hospital in Peru.
Match Strength: 3.403
There is a paucity of HIV autopsy data from South America and none that document the postmortem findings in patients with HIV/AIDS in Peru. The purpose of this autopsy study was to determine the spectrum of opportunistic infections and the causes of mortality in HIV-positive patients at a public hospital in Lima. Clinico-epidemiological information regarding HIV infection in Peru is also reviewed. Sixteen HIV-related hospital postmortems, performed between 1999 and 2004, were included in this retrospective analysis. The primary cause of death was established in 12 patients: one died of ... Read More »
» Published in Pathol Res Pract. 2006;202(11):767-75. Epub 2006 Sep 19.
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