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Peer Reviewed Scientific Research Reports.
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1. POZ for effect--POZ-ZF transcription factors in cancer and development.
Match Strength: 6.450
The BTB/POZ-ZF [Broad complex, Tramtrack, Bric a brac (BTB) or poxvirus and zinc finger (POZ)-zinc finger] protein family comprises a diverse group of transcription factors. POZ-ZF proteins have been implicated in many biological processes, including B cell fate determination, DNA damage responses, cell cycle progression and a multitude of developmental events, including gastrulation, limb formation and hematopoietic stem cell fate determination. Consequently, dysfunction of vertebrate POZ-ZF proteins, such as promyelocytic leukemia zinc finger (PLZF), B cell lymphoma 6 (Bcl-6), ... Read More »
» Published in Trends Cell Biol. 2006 Nov;16(11):578-87. Epub 2006 Sep 22.
2. Young patients with oral squamous cell carcinoma: study of the involvement of GSTP1 and deregulation of the Fanconi anemia genes.
Match Strength: 4.876
OBJECTIVE: To investigate whether oral squamous cell carcinomas (OSCCs) from young (=40 years) and older (>/=60 years) patients have differential expression levels of GSTP1, FANCA, FANCC, FANCD2, and FANCG. DESIGN: Quantitative real-time reverse transcriptase-polymerase chain reaction and immunohistochemical analysis were used to assess gene and protein expression, respectively. SETTING: This study was performed in a research institute within a hospital setting. PATIENTS: Our study group consisted of 104 patients (42 young and 62 older). We collected RNA from 32 OSCC samples (10 young ... Read More »
» Published in Arch Otolaryngol Head Neck Surg. 2006 Sep;132(9):958-66.
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