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Peer Reviewed Scientific Research Reports.
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1. Surgically correctable hypertension caused by primary aldosteronism.
Match Strength: 10.679
Surgically correctable forms of primary aldosteronism are generally held to be less common than forms requiring medical therapy. However, with the availability of improved diagnostic techniques and the adoption of a systematic and thorough diagnostic work-up they can be identified more commonly than expected. Adrenal vein sampling (AVS) for measurement of cortisol and aldosterone has emerged as the 'gold standard' diagnostic test for identifying unilateral causes of primary aldosteronism that are amenable to surgical cure. Adrenalectomy can provide long-term normalisation of blood pressure and ... Read More »
» Published in Best Pract Res Clin Endocrinol Metab. 2006 Sep;20(3):385-400.
2. Screening for primary aldosteronism.
Match Strength: 8.093
Normokalaemic manifestation of primary aldosteronism is a frequent cause of secondary hypertension. It occurs in approximately 5-12% of all patients with hypertension, primarily patients with severe and uncontrolled blood pressure. Main causes are bilateral adrenal hyperplasia (2/3 of cases) and aldosterone-producing adenoma (1/3 of cases). Screening is performed by measurement of the aldosterone/renin ratio, which is raised in affected patients. Suspicion of primary aldosteronism due to a pathological ratio requires confirmatory testing e.g. by saline infusion test or fludrocortisone ... Read More »
» Published in Best Pract Res Clin Endocrinol Metab. 2006 Sep;20(3):369-84.
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