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Peer Reviewed Scientific Research Reports.
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1. Posterior spinal epidural abscess: an unusual complication of vertebroplasty.
Match Strength: 7.899
OBJECTIVE: Complications after vertebroplasty are rare. There are few reported infectious complications requiring surgical management such as corpectomy with anterior reconstruction and posterior stabilization, although we have not seen any reports about epidural abscess in the literature. We present a patient in whom posterior epidural abscess developed after vertebroplasty in which drainage and antibiotherapy were required for treatment. METHODS: A 70-year-old female with a painful T12 osteoporotic compression fracture underwent percutaneous vertebroplasty using polymethylmethacrylate ... Read More »
» Published in Joint Bone Spine. 2006 Dec;73(6):753-5. Epub 2006 Apr 25.
2. Percutaneous CT scan-guided drainage vs. antibiotherapy alone for Hinchey II diverticulitis: a case-control study.
Match Strength: 6.281
PURPOSE: CT-scan-guided percutaneous abscess drainage of Hinchey Stage II diverticulitis is considered the best initial approach to treat conservatively the abscess and to subsequently perform an elective sigmoidectomy. However, drainage is not always technically feasible, may expose the patient to additional morbidity, and has not been critically evaluated in this indication. This study was undertaken to compare the results of percutaneous drainage vs. antibiotic therapy alone in patients with Hinchey II diverticulitis. METHODS: This was a case-control study of all patients who presented in ... Read More »
» Published in Dis Colon Rectum. 2006 Oct;49(10):1533-8.
3. Fatal Klebsiella pneumoniae meningitis and emphysematous brain abscess after endoscopic variceal ligation in a patient with liver cirrhosis and diabetes mellitus.
Match Strength: 5.468
Procedure-related bacterial infections may complicate esophageal variceal ligation in cirrhosis patients. Here, we report a 58-year-old man with underlying diabetes and liver cirrhosis who developed Klebsiella pneumoniae meningitis and brain abscess with gas formation in brain parenchyma and ventricles after this procedure. Despite administration of appropriate antimicrobial therapy, he became comatose on the 3rd day of acute illness and died on the 4th day of hospitalization. This case highlights the indication for antimicrobial prophylaxis in cirrhotic patients with gastrointestinal bleeding ... Read More »
» Published in J Formos Med Assoc. 2006 Oct;105(10):857-60.
4. Intracranial complications of sinusitis in children and adolescents and their outcomes.
Match Strength: 4.892
OBJECTIVE: To gain insight into patterns of presentation, imaging, microbiological aspects, therapy, disease course, and outcome of intracranial complications of sinusitis (ICS), which are challenging conditions with the potential to cause significant morbidity and mortality. We reviewed our experience with ICS in children and adolescents. DESIGN: Consecutive case series with a mean follow-up of 12 months. SETTING: Tertiary pediatric referral center. PATIENTS: Consecutive sample of 25 children and adolescents treated for 35 intracranial complications (mean age, 13.2 years [range, 4-18 years]). ... Read More »
» Published in Arch Otolaryngol Head Neck Surg. 2006 Sep;132(9):969-76.
5. Aberrant induction of regulatory activity of CD4+CD25+ T cells by dendritic cells in HIV-infected persons with amebic liver abscess.
Match Strength: 4.476
To know why HIV-1-infected persons are particularly susceptible to amebic liver abscess (ALA), we investigated the role of CD4CD25 T cells in the susceptibility of HIV-1-infected persons to this disease. Herein we show, in early stage HIV-1-infected subjects, that CD4 T-cell responses to Entamoeba histolytica antigen (EhAg) were selectively impaired, especially in those with ALA. EhAg-specific CD4 T-cell responses were normalized by depletion of CD4CD25 cells or by addition of anti-cytotoxic T lymphocyte antigen 4 (CTLA4) antibody. Regulatory activity of CD4CD25 T cells to suppress the EhAg ... Read More »
» Published in J Acquir Immune Defic Syndr. 2007 Jan 1;44(1):6-13.
6. Case report: epidural abscess in a parturient with pruritic urticarial papules and plaques of pregnancy (PUPPP).
Match Strength: 3.958
PURPOSE: To describe the risk factors for epidural abscess (EA) formation following epidural analgesia in a parturient with pruritic urticarial papules and plaques of pregnancy (PUPPP). CLINICAL FEATURES: A 33 yr-old gravida 2 nulliparous patient at 36 weeks gestation presented with severe pre-eclampsia, and PUPPP (treated with prednisone). Magnesium prophylaxis was started and labour was induced. An epidural catheter was placed at the L(3-4) level using standard aseptic technique. Bupivacaine was incrementally injected to achieve a T10 sensory level, and analgesia was maintained using a ... Read More »
» Published in Can J Anaesth. 2006 Oct;53(10):1010-4.
7. Endoscopic management of orbital abscesses.
Match Strength: 3.820
Orbital complications of sinusitis have declined in the postantibiotic era. Nonetheless, the development of a subperiosteal or intraorbital abscess remains a serious condition that is best managed through a multidisciplinary approach. Surgical management is almost always indicated when orbital collections are present, and medical therapy plays a complimentary role. The endoscopic approach of draining a medial orbital collection offers significant advantages over the traditional external approach. The preoperative and intraoperative use of computer-aided technology may be a useful adjunct in ... Read More »
» Published in Otolaryngol Clin North Am. 2006 Oct;39(5):1037-47, viii.
8. Prevalence of tubo-ovarian abscess in adolescents diagnosed with pelvic inflammatory disease in a pediatric emergency department.
Match Strength: 3.680
OBJECTIVES: The rate of tubo-ovarian abscess (TOA) in adolescents with pelvic inflammatory disease (PID) is reported to range from 17% to 20%. However, no reports have focused specifically on the adolescent patient presenting to the emergency department (ED), regardless of whether they are treated in the inpatient or outpatient setting. Recent changes in the 2002 Centers for Disease Control and Prevention (CDC) Guidelines for the Treatment of Sexually Transmitted Diseases and sexually transmitted infection screening programs are likely to have impacted both the prevalence of PID and the rates ... Read More »
» Published in Pediatr Emerg Care. 2006 Sep;22(9):621-5.
9. MR imaging of in vivo recruitment of iron oxide-labeled macrophages in experimentally induced soft-tissue infection in mice.
Match Strength: 3.644
PURPOSE: To evaluate the feasibility of magnetic resonance (MR) imaging in depicting in vivo recruitment of iron oxide-labeled macrophages in experimentally induced soft-tissue infection. MATERIALS AND METHODS: The study was performed according to the guidelines of the U.S. National Institutes of Health and recommendations of the committee on animal research. The protocol was approved by the local institutional review committee on animal care. Experimental soft-tissue infection in 12 mice was induced by inoculation with a 5 x 10(7) colony-forming units of Staphylococcus aureus into the left ... Read More »
» Published in Radiology. 2006 Oct;241(1):142-8.
10. Multi-detector row CT: spectrum of diseases involving the ileocecal area.
Match Strength: 2.612
The ileocecal area is a relatively short segment of the gastrointestinal tract but may be affected by pathologic conditions that are either common throughout the gastrointestinal system or exclusive to this area. These conditions include benign and malignant tumors, inflammatory processes (appendicitis, diverticulitis, epiploic appendagitis, Crohn disease), infectious diseases, and miscellaneous conditions (cecal ischemia, typhlitis, cecal volvulus, duplication cyst). The various components of the ileocecal area (cecum, appendix, ileocecal valve, terminal ileum) are close to one another, so ... Read More »
» Published in Radiographics. 2006 Sep-Oct;26(5):1373-90.
11. Molecular analysis of Filifactor alocis, Tannerella forsythia, and treponema denticola associated with primary endodontic infections and failed endodontic treatment.
Match Strength: 2.574
The aim of this study was to investigate the presence of strict anaerobes such as Filifactor alocis, Tannerella forsythia, and Treponema denticola in primary and secondary root-infected canals with periapical lesions by molecular analysis and the association of these species with specific endodontic signs and symptoms. Microbial samples were taken from 100 root canals, 50 with necrotic pulp tissues (NPT, primary infection), and 50 with failed endodontic treatment (FET, secondary infection). DNA was extracted from the samples, which were analyzed for the presence of three endodontic pathogens ... Read More »
» Published in J Endod. 2006 Oct;32(10):937-40. Epub 2006 Jul 26.
12. Endoscopic management of endometriosis.
Match Strength: 2.479
Randomized clinical trials in the effectiveness of laparoscopic surgery in the management of endometriosis associated with chronic pelvic pain show a 66% to 80% response rate. There is a 20% to 30% ''placebo'' response rate. The value of surgery for infertile patients with minimal and mild disease is still debated but is most likely small. In advanced disease, surgery clearly improves outcome, although the surgery is more challenging. After an initial unsuccessful surgery for restoration of fertility in patients with advanced endometriosis, in vitro fertilization rather than repeat surgery is ... Read More »
» Published in Minerva Ginecol. 2006 Oct;58(5):347-60.
13. Revision surgeries in cochlear implant patients: a review of 45 cases.
Match Strength: 2.446
The aim of this study was to analyze the causes for revision procedures, surgical findings and audiological outcome in reoperated cochlear implant patients. The medical records of 45 patients were reviewed retrospectively for age at the time of implantation, the implant was used for initial and revision surgeries, the duration of implant use before revision, surgical findings, and postoperative audiological results. Generally, children were reoperated more often than adults (12.5 vs. 6.9%) and, with one exception of improper electrode insertion, there were no major post-revision complications. ... Read More »
» Published in Eur Arch Otorhinolaryngol. 2007 Jan;264(1):3-7. Epub 2006 Sep 29.
14. Comparison of plain chest radiography and high-resolution computed tomography in human immunodeficiency virus infected patients with community-acquired pneumonia: a Sub-Saharan Africa study.
Match Strength: 2.389
The objective of the study was to determine the proportion of patients with missed lesions on plain chest radiographs compared with high-resolution computed tomography (HRCT) in 49 HIV infected patients with community-acquired pneumonia (CAP). Patients had plain chest radiography and HRCT scans of the chest at admission. Microbiological investigations for CAP were performed. An experienced radiologist, without knowledge of clinical or pathological data, reported the chest radiographs and HRCT scans. The study group included 26 females and 23 males, aged 18-53 years (mean age 36 years). ... Read More »
» Published in Br J Radiol. 2006 Sep 27;
15. Cannulation of the suprachoroidal space: a novel drug delivery methodology to the posterior segment.
Match Strength: 2.188
PURPOSE: To describe, test, and evaluate the pharmacokinetics of a novel posterior drug delivery system (PDS) by means of microcannulation of the suprachoroidal space in both the primate and pig animal model. DESIGN: Animal study. METHODS: A rhesus macaque (Macaca mulatta) (n = 1) and pig model (n = 93) were used to evaluate the PDS, a microcannula that combines a drug delivery channel with a fiber-optic illumination and optimal transition properties. The surgical technique, safety profile, histopathology, retinal and choroidal blood flow, injection of tracer dyes, and triamcinolone ... Read More »
» Published in Am J Ophthalmol. 2006 Nov;142(5):777-87. Epub 2006 Sep 20.
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