Go to Home Page...
 
Web Level1Diet.com
Subscribe to our RSS feeds...
Subscribe
 
Home Foods to Eat Foods to Avoid Exercise Supplements Weight Loss News Diabetes News Your Concerns Archived Reports

Bookmark Us: Yahoo Del.icio.us Simpy Technorati Email a friend Print



Protan color vision deficiency with a unique order of green-red as the first two genes of a visual pigment array.

<< Prev Report
Refine Your Search:

All Words Any Words
Next Report >>


Normal visual pigment gene arrays on the human X chromosome have a red gene at the first and a green gene at the second positions. More than half of the arrays have additional green genes downstream, but only the first two genes of the array are likely to be expressed in the retina. An array consisting of four genes in two Japanese participants, A121 and A447, was detected either by pulsed field gel electrophoresis and subsequent Southern hybridization or by single nucleotide primer extension reaction. In both participants, the first gene of the array was green, downstream genes were red and green, and the fourth gene was green. The red gene was determined to be at the second position by comparison of polymorphic sites among the intergenic regions that had been amplified by long-range PCR. Such an array with a reverse normal order of pigment genes, green-red as the first two, has never been reported before. They were expected to have normal color vision but showed protan deficiency (protanomaly), a phenotype lacking the red pigment. The red gene had no mutations in the exons and exon/intron boundaries, but had an A-71C substitution in the promoter in both participants. Publication Types: Research Support, Non-U.S. Gov't


Authored by Ueyama H, Tanabe S, Muraki-Oda S, Yamade S, Ohkubo I. Department of Biochemistry and Molecular Biology, Shiga University of Medical Science, Seta, Otsu 520-2192, Japan. datt@belle.shiga-med.ac.jp.

Published in J Hum Genet. 2006;51(8):686-94. Epub 2006 Jul 28. The full report is available online. link   A subscription to the periodical may be required.



<< Prev Report Next Report >>










* All information on Level1Diet.com is for educational purposes only. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Before changing your diet, or adding supplements to your diet, or beginning an exercise program, everyone should consult a qualified and licensed health practitioner; a physician, dietician or similar professional.




spacer spacer
spacer
   


DO YOU KNOW ?
Over 1,532 new health studies are published every day ― 559,288 per year. Join our weekly update program to stay informed...
spacer

spacer
» About Health Updates


spacer

Donate a few dollars
to help us promote
anti-inflammatory health.


spacer
Bigger Font Size Smaller Font Size Left Align Justify Align Right Align Bookmark This Page
spacer
Search 1.49 Million
Health Studies


» List of 4,000+ Diseases
spacer
   

spacer




Subscribe to
Level1Diet.com
Health Reports


Add to Google Reader or Homepage
Subscribe in NewsGator Online
Subscribe in Bloglines
Add to Excite MIX
Add to netvibes
Add to fwicki
Subscribe in NewsAlloy
Add to My AOL
Add to The Free Dictionary
Add to Pageflakes


[Valid RSS]



 
About Us Contact Us Privacy Free Newsletter Health FAQs Terms of Use

 Subscribe in a reader

© 2009 Level1Diet.com, All Rights Reserved.     Contact: