Anti-Inflammatory Diet Home Page...
Subscribe to Anti-Inflammatory Diet RSS feeds...
Free Anti-inflammatory diet summary... Anti-inflammation diet weight loss story... 
Home Foods to Eat Foods to Avoid Exercise Supplements Weight Loss News Diabetes News Your Concerns Archived Reports

Bookmark Us: Yahoo Simpy Technorati Email a friend Print

Regulation of autoimmune inflammation by pro-inflammatory cytokines.

<< Prev Report
Refine Your Search:

All Words Any Words
Next Report >>

The pro-inflammatory cytokines play a critical role in the initiation and propagation of autoimmune arthritis and many other disorders resulting from a dysregulated self-directed immune response. These cytokines influence the interplay among the cellular, immunological and biochemical mediators of inflammation at multiple levels. Regulation of the pro-inflammatory activity of these cytokines is generally perceived to be mediated by the anti-inflammatory and immunosuppressive cytokines such as IL-4, IL-10, or TGF-beta. However, increasing evidence is accumulating in support of the regulatory attributes of the pro-inflammatory cytokines themselves, in studies conducted in animal models of diabetes, multiple sclerosis, uveitis, and lupus. The results of our recent studies have shown that the pro-inflammatory cytokines, TNF-alpha and IFN-gamma, can suppress arthritic inflammation in rats, and also contribute to resistance against arthritis. These results are of paramount significance not only in fully understanding the pathogenesis of autoimmune arthritis, but also in anticipating the full ramifications of the in vivo neutralization of the pro-inflammatory cytokines, including that for therapeutic purposes.

Keywords: inflammatory cytokines, these cytokines, autoimmune arthritis, cytokines, inflammatory, arthritis

Authored by Kim EY, Moudgil KD. Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

Published in Immunol Lett. 2008 Oct 30;120(1-2):1-5. Epub 2008 Aug 9. The full report is available online. link   A subscription to the periodical may be required.

<< Prev Report Next Report >>

* All information on is for educational purposes only. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Before changing your diet, or adding supplements to your diet, or beginning an exercise program, everyone should consult a qualified and licensed health practitioner; a physician, dietician or similar professional.

spacer spacer
spacer foods to eat...

Over 1,532 new health studies are published every day ― 559,288 per year. Join our weekly update program to stay informed...

» About Health Updates



Donate $5 or $10
to help us promote
anti-inflammatory health.

Bigger Font Size Smaller Font Size Left Align Justify Align Right Align Bookmark This Page
Search 3.1 Million
Health Studies

» List of 4,000+ Diseases


Subscribe to
Health Reports

Add to Google Reader or Homepage
Subscribe in NewsGator Online
Subscribe in Bloglines
Add to Excite MIX
Add to netvibes
Add to fwicki
Add to My AOL
Add to The Free Dictionary

About Us Contact Us Privacy Free Newsletter Health FAQs Terms of Use

 Subscribe in a reader

© 2010, All Rights Reserved.     Contact:

Replace omega-6 vegetable oils with omega-9 olive oil... Eat oily fish like tuna, sardines, anchovy, salmon, herring... Beans, lentils, peas add fiber... Nine or more 3-ounce servings of fruits or vegetables per day...